| Full name: protein tyrosine phosphatase non-receptor type 9 | Alias Symbol: MEG2 | ||
| Type: protein-coding gene | Cytoband: 15q24.2 | ||
| Entrez ID: 5780 | HGNC ID: HGNC:9661 | Ensembl Gene: ENSG00000169410 | OMIM ID: 600768 |
| Drug and gene relationship at DGIdb | |||
Expression of PTPN9:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PTPN9 | 5780 | 202958_at | 0.0899 | 0.8905 | |
| GSE20347 | PTPN9 | 5780 | 202958_at | 0.5350 | 0.0000 | |
| GSE23400 | PTPN9 | 5780 | 202958_at | 0.1827 | 0.0000 | |
| GSE26886 | PTPN9 | 5780 | 202958_at | 0.7570 | 0.0007 | |
| GSE29001 | PTPN9 | 5780 | 202958_at | 0.2572 | 0.3088 | |
| GSE38129 | PTPN9 | 5780 | 202958_at | 0.5586 | 0.0000 | |
| GSE45670 | PTPN9 | 5780 | 202958_at | 0.3108 | 0.0061 | |
| GSE53622 | PTPN9 | 5780 | 126396 | 0.4492 | 0.0000 | |
| GSE53624 | PTPN9 | 5780 | 126396 | 0.6454 | 0.0000 | |
| GSE63941 | PTPN9 | 5780 | 202958_at | 0.8950 | 0.0150 | |
| GSE77861 | PTPN9 | 5780 | 202958_at | 0.3551 | 0.1497 | |
| GSE97050 | PTPN9 | 5780 | A_23_P124486 | 0.2100 | 0.3335 | |
| SRP007169 | PTPN9 | 5780 | RNAseq | 0.9953 | 0.0389 | |
| SRP008496 | PTPN9 | 5780 | RNAseq | 1.6753 | 0.0000 | |
| SRP064894 | PTPN9 | 5780 | RNAseq | 0.5861 | 0.0000 | |
| SRP133303 | PTPN9 | 5780 | RNAseq | 0.5483 | 0.0006 | |
| SRP159526 | PTPN9 | 5780 | RNAseq | 0.5992 | 0.0002 | |
| SRP193095 | PTPN9 | 5780 | RNAseq | 0.4774 | 0.0001 | |
| SRP219564 | PTPN9 | 5780 | RNAseq | 0.4053 | 0.3556 | |
| TCGA | PTPN9 | 5780 | RNAseq | 0.0259 | 0.5854 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by PTPN9 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PTPN9:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PTPN9 | 5780 | 8 | 1 | 21 | |
| GSE20123 | PTPN9 | 5780 | 8 | 1 | 21 | |
| GSE43470 | PTPN9 | 5780 | 4 | 6 | 33 | |
| GSE46452 | PTPN9 | 5780 | 3 | 7 | 49 | |
| GSE47630 | PTPN9 | 5780 | 8 | 10 | 22 | |
| GSE54993 | PTPN9 | 5780 | 5 | 6 | 59 | |
| GSE54994 | PTPN9 | 5780 | 5 | 6 | 42 | |
| GSE60625 | PTPN9 | 5780 | 4 | 0 | 7 | |
| GSE74703 | PTPN9 | 5780 | 4 | 3 | 29 | |
| GSE74704 | PTPN9 | 5780 | 4 | 1 | 15 | |
| TCGA | PTPN9 | 5780 | 14 | 15 | 67 |
Total number of gains: 67; Total number of losses: 56; Total Number of normals: 365.
Somatic mutations of PTPN9:
Generating mutation plots.
Highly correlated genes for PTPN9:
Showing top 20/1325 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PTPN9 | ERVW-1 | 0.77169 | 3 | 0 | 3 |
| PTPN9 | CHCHD5 | 0.768731 | 3 | 0 | 3 |
| PTPN9 | KRTCAP2 | 0.752826 | 4 | 0 | 4 |
| PTPN9 | COPE | 0.750935 | 3 | 0 | 3 |
| PTPN9 | PET117 | 0.748299 | 3 | 0 | 3 |
| PTPN9 | SLC39A3 | 0.738108 | 3 | 0 | 3 |
| PTPN9 | TTLL1 | 0.737548 | 3 | 0 | 3 |
| PTPN9 | SPOPL | 0.734993 | 3 | 0 | 3 |
| PTPN9 | TMTC1 | 0.730689 | 4 | 0 | 4 |
| PTPN9 | CWF19L1 | 0.725687 | 3 | 0 | 3 |
| PTPN9 | C17orf67 | 0.721745 | 3 | 0 | 3 |
| PTPN9 | SAMD1 | 0.721451 | 3 | 0 | 3 |
| PTPN9 | NELL1 | 0.71896 | 3 | 0 | 3 |
| PTPN9 | TMEM11 | 0.718434 | 3 | 0 | 3 |
| PTPN9 | WWC3 | 0.717491 | 4 | 0 | 4 |
| PTPN9 | ADCK2 | 0.716397 | 3 | 0 | 3 |
| PTPN9 | LRRC58 | 0.713928 | 3 | 0 | 3 |
| PTPN9 | ACO2 | 0.713054 | 3 | 0 | 3 |
| PTPN9 | POLRMT | 0.711388 | 4 | 0 | 4 |
| PTPN9 | SLC35B2 | 0.710865 | 3 | 0 | 3 |
For details and further investigation, click here
