| Full name: zinc finger and BTB domain containing 25 | Alias Symbol: KUP | ||
| Type: protein-coding gene | Cytoband: 14q23.3 | ||
| Entrez ID: 7597 | HGNC ID: HGNC:13112 | Ensembl Gene: ENSG00000089775 | OMIM ID: 194541 |
| Drug and gene relationship at DGIdb | |||
Expression of ZBTB25:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZBTB25 | 7597 | 214482_at | -0.0672 | 0.8823 | |
| GSE20347 | ZBTB25 | 7597 | 214482_at | 0.4167 | 0.0000 | |
| GSE23400 | ZBTB25 | 7597 | 214482_at | 0.1027 | 0.0046 | |
| GSE26886 | ZBTB25 | 7597 | 214482_at | 0.8602 | 0.0004 | |
| GSE29001 | ZBTB25 | 7597 | 214482_at | 0.3021 | 0.1171 | |
| GSE38129 | ZBTB25 | 7597 | 214482_at | 0.2943 | 0.0006 | |
| GSE45670 | ZBTB25 | 7597 | 214482_at | 0.2175 | 0.2409 | |
| GSE53622 | ZBTB25 | 7597 | 37317 | 0.6879 | 0.0000 | |
| GSE53624 | ZBTB25 | 7597 | 37317 | 0.6643 | 0.0000 | |
| GSE63941 | ZBTB25 | 7597 | 214482_at | 0.8514 | 0.0261 | |
| GSE77861 | ZBTB25 | 7597 | 214482_at | 0.2836 | 0.2413 | |
| GSE97050 | ZBTB25 | 7597 | A_23_P48628 | 0.4455 | 0.1476 | |
| SRP007169 | ZBTB25 | 7597 | RNAseq | 0.9239 | 0.0171 | |
| SRP008496 | ZBTB25 | 7597 | RNAseq | 1.0753 | 0.0000 | |
| SRP064894 | ZBTB25 | 7597 | RNAseq | 0.6605 | 0.0017 | |
| SRP133303 | ZBTB25 | 7597 | RNAseq | 0.0880 | 0.6881 | |
| SRP159526 | ZBTB25 | 7597 | RNAseq | 0.2308 | 0.5269 | |
| SRP193095 | ZBTB25 | 7597 | RNAseq | 0.4726 | 0.0000 | |
| SRP219564 | ZBTB25 | 7597 | RNAseq | 0.3221 | 0.3403 | |
| TCGA | ZBTB25 | 7597 | RNAseq | 0.0569 | 0.4395 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ZBTB25 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZBTB25:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZBTB25 | 7597 | 7 | 3 | 20 | |
| GSE20123 | ZBTB25 | 7597 | 7 | 3 | 20 | |
| GSE43470 | ZBTB25 | 7597 | 8 | 2 | 33 | |
| GSE46452 | ZBTB25 | 7597 | 16 | 3 | 40 | |
| GSE47630 | ZBTB25 | 7597 | 11 | 9 | 20 | |
| GSE54993 | ZBTB25 | 7597 | 3 | 9 | 58 | |
| GSE54994 | ZBTB25 | 7597 | 18 | 5 | 30 | |
| GSE60625 | ZBTB25 | 7597 | 0 | 2 | 9 | |
| GSE74703 | ZBTB25 | 7597 | 7 | 2 | 27 | |
| GSE74704 | ZBTB25 | 7597 | 3 | 2 | 15 | |
| TCGA | ZBTB25 | 7597 | 32 | 14 | 50 |
Total number of gains: 112; Total number of losses: 54; Total Number of normals: 322.
Somatic mutations of ZBTB25:
Generating mutation plots.
Highly correlated genes for ZBTB25:
Showing top 20/935 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZBTB25 | ADCK2 | 0.777909 | 3 | 0 | 3 |
| ZBTB25 | DYNLRB1 | 0.758079 | 3 | 0 | 3 |
| ZBTB25 | LRRC58 | 0.743655 | 3 | 0 | 3 |
| ZBTB25 | PPP1R35 | 0.731109 | 4 | 0 | 4 |
| ZBTB25 | LRRC8C | 0.725099 | 3 | 0 | 3 |
| ZBTB25 | TCN2 | 0.724884 | 3 | 0 | 3 |
| ZBTB25 | EIF1B | 0.718213 | 3 | 0 | 3 |
| ZBTB25 | ANG | 0.713343 | 4 | 0 | 4 |
| ZBTB25 | C6orf141 | 0.713079 | 3 | 0 | 3 |
| ZBTB25 | AKR1E2 | 0.712011 | 3 | 0 | 3 |
| ZBTB25 | MRPL10 | 0.706079 | 4 | 0 | 4 |
| ZBTB25 | ATF1 | 0.70588 | 3 | 0 | 3 |
| ZBTB25 | LMBR1 | 0.703171 | 4 | 0 | 4 |
| ZBTB25 | JMY | 0.702451 | 3 | 0 | 3 |
| ZBTB25 | STK4 | 0.701892 | 3 | 0 | 3 |
| ZBTB25 | POGZ | 0.700518 | 4 | 0 | 3 |
| ZBTB25 | HAUS4 | 0.697922 | 3 | 0 | 3 |
| ZBTB25 | CLDN12 | 0.694668 | 4 | 0 | 4 |
| ZBTB25 | RAB34 | 0.690484 | 3 | 0 | 3 |
| ZBTB25 | TES | 0.68735 | 4 | 0 | 4 |
For details and further investigation, click here
