| Full name: ATR interacting protein | Alias Symbol: FLJ12343|MGC20625|MGC21482|MGC26740 | ||
| Type: protein-coding gene | Cytoband: 3p21.31 | ||
| Entrez ID: 84126 | HGNC ID: HGNC:33499 | Ensembl Gene: ENSG00000164053 | OMIM ID: 606605 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
ATRIP involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa03460 | Fanconi anemia pathway |
Expression of ATRIP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | ATRIP | 84126 | 114904 | 0.0132 | 0.9028 | |
| GSE53624 | ATRIP | 84126 | 114904 | 0.1932 | 0.0137 | |
| GSE97050 | ATRIP | 84126 | A_24_P371425 | 0.2925 | 0.2589 | |
| SRP007169 | ATRIP | 84126 | RNAseq | 0.0633 | 0.8825 | |
| SRP064894 | ATRIP | 84126 | RNAseq | 0.4591 | 0.0646 | |
| SRP133303 | ATRIP | 84126 | RNAseq | -0.4006 | 0.0074 | |
| SRP159526 | ATRIP | 84126 | RNAseq | 0.1244 | 0.7110 | |
| SRP193095 | ATRIP | 84126 | RNAseq | 0.0065 | 0.9529 | |
| SRP219564 | ATRIP | 84126 | RNAseq | 0.0290 | 0.9505 | |
| TCGA | ATRIP | 84126 | RNAseq | 0.0943 | 0.1548 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ATRIP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ATRIP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ATRIP | 84126 | 0 | 18 | 12 | |
| GSE20123 | ATRIP | 84126 | 0 | 19 | 11 | |
| GSE43470 | ATRIP | 84126 | 0 | 19 | 24 | |
| GSE46452 | ATRIP | 84126 | 2 | 17 | 40 | |
| GSE47630 | ATRIP | 84126 | 1 | 24 | 15 | |
| GSE54993 | ATRIP | 84126 | 6 | 2 | 62 | |
| GSE54994 | ATRIP | 84126 | 0 | 36 | 17 | |
| GSE60625 | ATRIP | 84126 | 5 | 0 | 6 | |
| GSE74703 | ATRIP | 84126 | 0 | 15 | 21 | |
| GSE74704 | ATRIP | 84126 | 0 | 12 | 8 | |
| TCGA | ATRIP | 84126 | 0 | 77 | 19 |
Total number of gains: 14; Total number of losses: 239; Total Number of normals: 235.
Somatic mutations of ATRIP:
Generating mutation plots.
Highly correlated genes for ATRIP:
Showing top 20/59 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ATRIP | WDR4 | 0.812149 | 3 | 0 | 3 |
| ATRIP | IFRD2 | 0.786773 | 3 | 0 | 3 |
| ATRIP | LARS2 | 0.783005 | 3 | 0 | 3 |
| ATRIP | MRPL37 | 0.746006 | 3 | 0 | 3 |
| ATRIP | RRP9 | 0.733253 | 3 | 0 | 3 |
| ATRIP | FARSA | 0.731854 | 3 | 0 | 3 |
| ATRIP | CDC25A | 0.730867 | 3 | 0 | 3 |
| ATRIP | RAD18 | 0.730276 | 3 | 0 | 3 |
| ATRIP | RHOG | 0.722965 | 3 | 0 | 3 |
| ATRIP | NME6 | 0.715282 | 3 | 0 | 3 |
| ATRIP | COX10 | 0.706128 | 3 | 0 | 3 |
| ATRIP | THG1L | 0.705642 | 3 | 0 | 3 |
| ATRIP | PIAS4 | 0.705095 | 3 | 0 | 3 |
| ATRIP | RPUSD3 | 0.705074 | 3 | 0 | 3 |
| ATRIP | ADCK2 | 0.704666 | 3 | 0 | 3 |
| ATRIP | FZR1 | 0.701242 | 3 | 0 | 3 |
| ATRIP | BABAM1 | 0.699518 | 3 | 0 | 3 |
| ATRIP | PIGH | 0.699419 | 3 | 0 | 3 |
| ATRIP | VRK3 | 0.699236 | 3 | 0 | 3 |
| ATRIP | ZFPL1 | 0.698964 | 3 | 0 | 3 |
For details and further investigation, click here
