| Full name: vacuolar protein sorting 36 homolog | Alias Symbol: CGI-145|Eap45 | ||
| Type: protein-coding gene | Cytoband: 13q14.3 | ||
| Entrez ID: 51028 | HGNC ID: HGNC:20312 | Ensembl Gene: ENSG00000136100 | OMIM ID: 610903 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of VPS36:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | VPS36 | 51028 | 222478_at | -0.3717 | 0.3859 | |
| GSE26886 | VPS36 | 51028 | 222478_at | -0.2855 | 0.4215 | |
| GSE45670 | VPS36 | 51028 | 222478_at | -0.4569 | 0.0187 | |
| GSE53622 | VPS36 | 51028 | 66768 | -0.6150 | 0.0000 | |
| GSE53624 | VPS36 | 51028 | 66768 | -0.7791 | 0.0000 | |
| GSE63941 | VPS36 | 51028 | 222478_at | -1.0313 | 0.0322 | |
| GSE77861 | VPS36 | 51028 | 222478_at | -0.5735 | 0.1801 | |
| GSE97050 | VPS36 | 51028 | A_33_P3674851 | -0.5232 | 0.0857 | |
| SRP007169 | VPS36 | 51028 | RNAseq | -0.5603 | 0.1118 | |
| SRP008496 | VPS36 | 51028 | RNAseq | -0.0979 | 0.7544 | |
| SRP064894 | VPS36 | 51028 | RNAseq | -0.6566 | 0.0056 | |
| SRP133303 | VPS36 | 51028 | RNAseq | -0.5099 | 0.0025 | |
| SRP159526 | VPS36 | 51028 | RNAseq | -0.9134 | 0.0034 | |
| SRP193095 | VPS36 | 51028 | RNAseq | -0.7019 | 0.0000 | |
| SRP219564 | VPS36 | 51028 | RNAseq | -0.8589 | 0.0393 | |
| TCGA | VPS36 | 51028 | RNAseq | -0.0707 | 0.1578 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by VPS36 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of VPS36:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | VPS36 | 51028 | 2 | 12 | 16 | |
| GSE20123 | VPS36 | 51028 | 2 | 11 | 17 | |
| GSE43470 | VPS36 | 51028 | 3 | 12 | 28 | |
| GSE46452 | VPS36 | 51028 | 0 | 32 | 27 | |
| GSE47630 | VPS36 | 51028 | 2 | 27 | 11 | |
| GSE54993 | VPS36 | 51028 | 12 | 2 | 56 | |
| GSE54994 | VPS36 | 51028 | 1 | 15 | 37 | |
| GSE60625 | VPS36 | 51028 | 0 | 3 | 8 | |
| GSE74703 | VPS36 | 51028 | 3 | 10 | 23 | |
| GSE74704 | VPS36 | 51028 | 0 | 9 | 11 | |
| TCGA | VPS36 | 51028 | 10 | 35 | 51 |
Total number of gains: 35; Total number of losses: 168; Total Number of normals: 285.
Somatic mutations of VPS36:
Generating mutation plots.
Highly correlated genes for VPS36:
Showing top 20/884 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| VPS36 | ZNF564 | 0.797529 | 4 | 0 | 4 |
| VPS36 | ANKRD6 | 0.782282 | 3 | 0 | 3 |
| VPS36 | RAD17 | 0.756008 | 3 | 0 | 3 |
| VPS36 | SRR | 0.754791 | 3 | 0 | 3 |
| VPS36 | SCAF11 | 0.746075 | 3 | 0 | 3 |
| VPS36 | ADCK2 | 0.745281 | 3 | 0 | 3 |
| VPS36 | BNIP2 | 0.745054 | 3 | 0 | 3 |
| VPS36 | DTWD1 | 0.739064 | 3 | 0 | 3 |
| VPS36 | ATF1 | 0.73874 | 3 | 0 | 3 |
| VPS36 | IFT81 | 0.73689 | 3 | 0 | 3 |
| VPS36 | ZNF248 | 0.732927 | 3 | 0 | 3 |
| VPS36 | YTHDF3 | 0.732709 | 3 | 0 | 3 |
| VPS36 | RCBTB1 | 0.731483 | 3 | 0 | 3 |
| VPS36 | DNAJC3 | 0.72276 | 4 | 0 | 4 |
| VPS36 | ANKRA2 | 0.715974 | 5 | 0 | 4 |
| VPS36 | ATXN7L3B | 0.715327 | 3 | 0 | 3 |
| VPS36 | MCCC1 | 0.708894 | 3 | 0 | 3 |
| VPS36 | GSTK1 | 0.705921 | 6 | 0 | 6 |
| VPS36 | ZNF528 | 0.704394 | 3 | 0 | 3 |
| VPS36 | TEX261 | 0.704332 | 3 | 0 | 3 |
For details and further investigation, click here
