DUS4L

 

Full name: dihydrouridine synthase 4 like Alias Symbol: PP35|DUS4
Type: protein-coding gene Cytoband: 7q22.3
Entrez ID: 11062 HGNC ID: HGNC:21517 Ensembl Gene: ENSG00000105865 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of DUS4L:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 DUS4L 11062 205761_s_at 0.0449 0.9518
GSE20347 DUS4L 11062 205761_s_at 0.7343 0.0049
GSE23400 DUS4L 11062 205761_s_at 0.4289 0.0000
GSE26886 DUS4L 11062 205761_s_at 0.0993 0.7848
GSE29001 DUS4L 11062 205761_s_at 0.4909 0.1888
GSE38129 DUS4L 11062 205761_s_at 0.9517 0.0000
GSE45670 DUS4L 11062 205761_s_at 0.5874 0.0100
GSE53622 DUS4L 11062 61956 0.9295 0.0000
GSE53624 DUS4L 11062 61956 0.9071 0.0000
GSE63941 DUS4L 11062 205761_s_at 1.0695 0.0429
GSE77861 DUS4L 11062 205761_s_at 0.6306 0.0138
GSE97050 DUS4L 11062 A_23_P215778 0.5654 0.1840
SRP007169 DUS4L 11062 RNAseq 0.4219 0.3654
SRP008496 DUS4L 11062 RNAseq 0.4617 0.2216
SRP064894 DUS4L 11062 RNAseq 0.1240 0.5668
SRP133303 DUS4L 11062 RNAseq 0.6878 0.0003
SRP159526 DUS4L 11062 RNAseq 0.3259 0.1935
SRP193095 DUS4L 11062 RNAseq 0.6049 0.0034
SRP219564 DUS4L 11062 RNAseq 0.5819 0.1955
TCGA DUS4L 11062 RNAseq 0.3467 0.0000

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by DUS4L expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of DUS4L:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 DUS4L 11062 12 0 18
GSE20123 DUS4L 11062 12 0 18
GSE43470 DUS4L 11062 6 2 35
GSE46452 DUS4L 11062 10 1 48
GSE47630 DUS4L 11062 8 3 29
GSE54993 DUS4L 11062 2 9 59
GSE54994 DUS4L 11062 16 3 34
GSE60625 DUS4L 11062 0 0 11
GSE74703 DUS4L 11062 6 2 28
GSE74704 DUS4L 11062 8 0 12
TCGA DUS4L 11062 50 10 36

Total number of gains: 130; Total number of losses: 30; Total Number of normals: 328.  

 

Somatic mutations of DUS4L:

 

Generating mutation plots.

 

Highly correlated genes for DUS4L:

 

Showing top 20/1433 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
DUS4LADCK20.762679303
DUS4LORC50.75709312011
DUS4LMMS22L0.742012303
DUS4LPUS70.73996911011
DUS4LDKC10.737534303
DUS4LUBE2T0.731332605
DUS4LPPP1R350.723793606
DUS4LNPAT0.710864303
DUS4LRB10.705458303
DUS4LNOP560.704528303
DUS4LPCNA0.69494710010
DUS4LPYCR20.693158303
DUS4LPSMC20.69275713011
DUS4LCBLL10.688259909
DUS4LTBL20.6880231009
DUS4LUCK20.687834303
DUS4LPNPT10.686507505
DUS4LRFC20.68355211011
DUS4LDHX330.681668706
DUS4LDESI20.677502707

For details and further investigation, click here