| Full name: nuclear RNA export factor 1 | Alias Symbol: TAP|Mex67|DKFZp667O0311 | ||
| Type: protein-coding gene | Cytoband: 11q12.3 | ||
| Entrez ID: 10482 | HGNC ID: HGNC:8071 | Ensembl Gene: ENSG00000162231 | OMIM ID: 602647 |
| Drug and gene relationship at DGIdb | |||
Expression of NXF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NXF1 | 10482 | 208922_s_at | -0.1189 | 0.8690 | |
| GSE20347 | NXF1 | 10482 | 208922_s_at | -0.0406 | 0.7397 | |
| GSE23400 | NXF1 | 10482 | 208922_s_at | 0.0112 | 0.8336 | |
| GSE26886 | NXF1 | 10482 | 208922_s_at | 0.2241 | 0.3982 | |
| GSE29001 | NXF1 | 10482 | 208922_s_at | -0.0622 | 0.8582 | |
| GSE38129 | NXF1 | 10482 | 208922_s_at | -0.1186 | 0.1804 | |
| GSE45670 | NXF1 | 10482 | 208922_s_at | -0.0431 | 0.6687 | |
| GSE53622 | NXF1 | 10482 | 60452 | 0.1445 | 0.0262 | |
| GSE53624 | NXF1 | 10482 | 60452 | 0.1097 | 0.1021 | |
| GSE63941 | NXF1 | 10482 | 208922_s_at | 0.5425 | 0.0746 | |
| GSE77861 | NXF1 | 10482 | 208922_s_at | 0.1470 | 0.4270 | |
| GSE97050 | NXF1 | 10482 | A_23_P13359 | -0.0228 | 0.9294 | |
| SRP007169 | NXF1 | 10482 | RNAseq | -0.1330 | 0.6850 | |
| SRP008496 | NXF1 | 10482 | RNAseq | 0.1145 | 0.5484 | |
| SRP064894 | NXF1 | 10482 | RNAseq | 0.1197 | 0.4117 | |
| SRP133303 | NXF1 | 10482 | RNAseq | -0.1957 | 0.1056 | |
| SRP159526 | NXF1 | 10482 | RNAseq | -0.1971 | 0.2857 | |
| SRP193095 | NXF1 | 10482 | RNAseq | 0.1915 | 0.1420 | |
| SRP219564 | NXF1 | 10482 | RNAseq | -0.2029 | 0.3624 | |
| TCGA | NXF1 | 10482 | RNAseq | -0.0020 | 0.9650 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NXF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NXF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NXF1 | 10482 | 6 | 5 | 19 | |
| GSE20123 | NXF1 | 10482 | 6 | 5 | 19 | |
| GSE43470 | NXF1 | 10482 | 1 | 6 | 36 | |
| GSE46452 | NXF1 | 10482 | 8 | 4 | 47 | |
| GSE47630 | NXF1 | 10482 | 3 | 7 | 30 | |
| GSE54993 | NXF1 | 10482 | 3 | 0 | 67 | |
| GSE54994 | NXF1 | 10482 | 5 | 5 | 43 | |
| GSE60625 | NXF1 | 10482 | 0 | 3 | 8 | |
| GSE74703 | NXF1 | 10482 | 1 | 3 | 32 | |
| GSE74704 | NXF1 | 10482 | 4 | 3 | 13 | |
| TCGA | NXF1 | 10482 | 12 | 11 | 73 |
Total number of gains: 49; Total number of losses: 52; Total Number of normals: 387.
Somatic mutations of NXF1:
Generating mutation plots.
Highly correlated genes for NXF1:
Showing top 20/231 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NXF1 | TTLL1 | 0.749895 | 3 | 0 | 3 |
| NXF1 | NSMCE4A | 0.746164 | 3 | 0 | 3 |
| NXF1 | JTB | 0.744749 | 3 | 0 | 3 |
| NXF1 | VPS28 | 0.741138 | 3 | 0 | 3 |
| NXF1 | DHX35 | 0.739901 | 3 | 0 | 3 |
| NXF1 | NVL | 0.737113 | 3 | 0 | 3 |
| NXF1 | LSM11 | 0.721504 | 3 | 0 | 3 |
| NXF1 | LEMD2 | 0.720928 | 5 | 0 | 5 |
| NXF1 | MEPCE | 0.720692 | 4 | 0 | 3 |
| NXF1 | ADCK2 | 0.720327 | 3 | 0 | 3 |
| NXF1 | PCGF2 | 0.710771 | 3 | 0 | 3 |
| NXF1 | ZNF764 | 0.710644 | 3 | 0 | 3 |
| NXF1 | PRRC2A | 0.706166 | 3 | 0 | 3 |
| NXF1 | SNRPA | 0.703238 | 3 | 0 | 3 |
| NXF1 | TUBA1B | 0.701561 | 3 | 0 | 3 |
| NXF1 | PI16 | 0.701335 | 3 | 0 | 3 |
| NXF1 | FAM20B | 0.696919 | 4 | 0 | 4 |
| NXF1 | FAM200B | 0.695204 | 3 | 0 | 3 |
| NXF1 | DNAH14 | 0.695028 | 3 | 0 | 3 |
| NXF1 | RRP9 | 0.693981 | 3 | 0 | 3 |
For details and further investigation, click here
