| Full name: ribosomal protein S21 | Alias Symbol: S21 | ||
| Type: protein-coding gene | Cytoband: 20q13.33 | ||
| Entrez ID: 6227 | HGNC ID: HGNC:10409 | Ensembl Gene: ENSG00000171858 | OMIM ID: 180477 |
| Drug and gene relationship at DGIdb | |||
Expression of RPS21:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RPS21 | 6227 | 200834_s_at | 0.1601 | 0.4694 | |
| GSE20347 | RPS21 | 6227 | 200834_s_at | 0.1329 | 0.1919 | |
| GSE23400 | RPS21 | 6227 | 200834_s_at | 0.1614 | 0.0931 | |
| GSE26886 | RPS21 | 6227 | 200834_s_at | 0.3350 | 0.0212 | |
| GSE29001 | RPS21 | 6227 | 200834_s_at | 0.0198 | 0.9587 | |
| GSE38129 | RPS21 | 6227 | 200834_s_at | 0.1653 | 0.0581 | |
| GSE45670 | RPS21 | 6227 | 200834_s_at | -0.0617 | 0.5930 | |
| GSE53622 | RPS21 | 6227 | 85050 | 0.0247 | 0.7515 | |
| GSE53624 | RPS21 | 6227 | 85050 | 0.1977 | 0.0129 | |
| GSE63941 | RPS21 | 6227 | 200834_s_at | 0.8283 | 0.0005 | |
| GSE77861 | RPS21 | 6227 | 200834_s_at | -0.0480 | 0.8031 | |
| GSE97050 | RPS21 | 6227 | A_23_P120660 | 0.2261 | 0.4847 | |
| SRP007169 | RPS21 | 6227 | RNAseq | -0.8634 | 0.0106 | |
| SRP008496 | RPS21 | 6227 | RNAseq | -0.7639 | 0.0001 | |
| SRP064894 | RPS21 | 6227 | RNAseq | 0.1848 | 0.5830 | |
| SRP133303 | RPS21 | 6227 | RNAseq | -0.1125 | 0.3844 | |
| SRP159526 | RPS21 | 6227 | RNAseq | -0.3281 | 0.1635 | |
| SRP193095 | RPS21 | 6227 | RNAseq | -0.6838 | 0.0001 | |
| SRP219564 | RPS21 | 6227 | RNAseq | 0.2281 | 0.6042 | |
| TCGA | RPS21 | 6227 | RNAseq | 0.1398 | 0.0053 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RPS21 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RPS21:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RPS21 | 6227 | 13 | 2 | 15 | |
| GSE20123 | RPS21 | 6227 | 14 | 2 | 14 | |
| GSE43470 | RPS21 | 6227 | 11 | 1 | 31 | |
| GSE46452 | RPS21 | 6227 | 35 | 0 | 24 | |
| GSE47630 | RPS21 | 6227 | 25 | 1 | 14 | |
| GSE54993 | RPS21 | 6227 | 0 | 17 | 53 | |
| GSE54994 | RPS21 | 6227 | 29 | 0 | 24 | |
| GSE60625 | RPS21 | 6227 | 0 | 0 | 11 | |
| GSE74703 | RPS21 | 6227 | 10 | 0 | 26 | |
| GSE74704 | RPS21 | 6227 | 11 | 0 | 9 | |
| TCGA | RPS21 | 6227 | 43 | 4 | 49 |
Total number of gains: 191; Total number of losses: 27; Total Number of normals: 270.
Somatic mutations of RPS21:
Generating mutation plots.
Highly correlated genes for RPS21:
Showing top 20/735 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RPS21 | SLC7A6OS | 0.849295 | 3 | 0 | 3 |
| RPS21 | RPUSD4 | 0.807555 | 3 | 0 | 3 |
| RPS21 | LIN52 | 0.806254 | 3 | 0 | 3 |
| RPS21 | MAP3K13 | 0.783634 | 3 | 0 | 3 |
| RPS21 | NEDD1 | 0.775808 | 3 | 0 | 3 |
| RPS21 | UBTD2 | 0.774948 | 3 | 0 | 3 |
| RPS21 | SCO1 | 0.757768 | 3 | 0 | 3 |
| RPS21 | NUDCD1 | 0.756737 | 3 | 0 | 3 |
| RPS21 | EIF2D | 0.756364 | 3 | 0 | 3 |
| RPS21 | TMED8 | 0.750793 | 4 | 0 | 4 |
| RPS21 | TSEN15 | 0.746923 | 3 | 0 | 3 |
| RPS21 | DPY19L4 | 0.734897 | 3 | 0 | 3 |
| RPS21 | RAD21 | 0.734715 | 3 | 0 | 3 |
| RPS21 | LRRCC1 | 0.731585 | 3 | 0 | 3 |
| RPS21 | MSH6 | 0.730994 | 3 | 0 | 3 |
| RPS21 | PHF20 | 0.730015 | 4 | 0 | 4 |
| RPS21 | MARK1 | 0.724859 | 3 | 0 | 3 |
| RPS21 | POLR2K | 0.724032 | 3 | 0 | 3 |
| RPS21 | ADCK2 | 0.720434 | 3 | 0 | 3 |
| RPS21 | ANP32E | 0.718364 | 4 | 0 | 4 |
For details and further investigation, click here
