SUPT3H

 

Full name: SPT3 homolog, SAGA and STAGA complex component Alias Symbol: SPT3|SPT3L
Type: protein-coding gene Cytoband: 6p21.1
Entrez ID: 8464 HGNC ID: HGNC:11466 Ensembl Gene: ENSG00000196284 OMIM ID: 602947
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of SUPT3H:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SUPT3H 8464 206506_s_at 0.1898 0.7160
GSE20347 SUPT3H 8464 206506_s_at 0.6613 0.0006
GSE23400 SUPT3H 8464 206506_s_at 0.2894 0.0000
GSE26886 SUPT3H 8464 206506_s_at 1.9672 0.0000
GSE29001 SUPT3H 8464 206506_s_at 0.5441 0.1330
GSE38129 SUPT3H 8464 206506_s_at 0.7029 0.0000
GSE45670 SUPT3H 8464 206506_s_at 0.5341 0.0356
GSE53622 SUPT3H 8464 62051 0.4775 0.0087
GSE53624 SUPT3H 8464 41102 0.9059 0.0000
GSE63941 SUPT3H 8464 206506_s_at 0.7067 0.3563
GSE77861 SUPT3H 8464 206506_s_at 0.3811 0.1865
GSE97050 SUPT3H 8464 A_33_P3347152 -0.1835 0.3599
SRP007169 SUPT3H 8464 RNAseq 0.7858 0.1517
SRP008496 SUPT3H 8464 RNAseq 0.6547 0.0891
SRP064894 SUPT3H 8464 RNAseq 1.0228 0.0000
SRP133303 SUPT3H 8464 RNAseq 0.9099 0.0000
SRP159526 SUPT3H 8464 RNAseq 0.8128 0.0099
SRP193095 SUPT3H 8464 RNAseq 0.8558 0.0000
SRP219564 SUPT3H 8464 RNAseq 1.0325 0.0000
TCGA SUPT3H 8464 RNAseq 0.2795 0.0040

Upregulated datasets: 3; Downregulated datasets: 0.  

 

Survival by SUPT3H expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of SUPT3H:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SUPT3H 8464 6 2 22
GSE20123 SUPT3H 8464 6 2 22
GSE43470 SUPT3H 8464 6 0 37
GSE46452 SUPT3H 8464 2 10 47
GSE47630 SUPT3H 8464 8 4 28
GSE54993 SUPT3H 8464 3 2 65
GSE54994 SUPT3H 8464 9 3 41
GSE60625 SUPT3H 8464 0 3 8
GSE74703 SUPT3H 8464 6 0 30
GSE74704 SUPT3H 8464 2 1 17
TCGA SUPT3H 8464 18 18 60

Total number of gains: 66; Total number of losses: 45; Total Number of normals: 377.  

 

Somatic mutations of SUPT3H:

 

Generating mutation plots.

 

Highly correlated genes for SUPT3H:

 

Showing top 20/728 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SUPT3HSPATA170.727764404
SUPT3HBMP8B0.717055303
SUPT3HGPX80.704877505
SUPT3HJAKMIP30.69567303
SUPT3HJKAMP0.695052404
SUPT3HGEMIN60.69218808
SUPT3HC6orf1410.688353404
SUPT3HTIGD10.681284303
SUPT3HC20orf1940.680401303
SUPT3HTTC7B0.673336504
SUPT3HIFT430.671524605
SUPT3HPOLE40.668462404
SUPT3HACBD60.665417404
SUPT3HZNF5580.659555403
SUPT3HNAP1L10.657496403
SUPT3HC12orf650.65676303
SUPT3HBYSL0.655178909
SUPT3HVBP10.654468807
SUPT3HDGUOK0.652799706
SUPT3HTTC9C0.652378403

For details and further investigation, click here