| Full name: ESF1 nucleolar pre-rRNA processing protein homolog | Alias Symbol: bA526K24.1 | ||
| Type: protein-coding gene | Cytoband: 20p12.1 | ||
| Entrez ID: 51575 | HGNC ID: HGNC:15898 | Ensembl Gene: ENSG00000089048 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of ESF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ESF1 | 51575 | 218859_s_at | 0.4310 | 0.6252 | |
| GSE20347 | ESF1 | 51575 | 218859_s_at | 0.4954 | 0.0095 | |
| GSE23400 | ESF1 | 51575 | 218859_s_at | 0.4112 | 0.0009 | |
| GSE26886 | ESF1 | 51575 | 218859_s_at | 0.1564 | 0.6351 | |
| GSE29001 | ESF1 | 51575 | 218859_s_at | 0.4730 | 0.0961 | |
| GSE38129 | ESF1 | 51575 | 218859_s_at | 0.4932 | 0.0099 | |
| GSE45670 | ESF1 | 51575 | 218859_s_at | 0.4364 | 0.0307 | |
| GSE53622 | ESF1 | 51575 | 32165 | 0.6345 | 0.0000 | |
| GSE53624 | ESF1 | 51575 | 19008 | 0.7219 | 0.0000 | |
| GSE63941 | ESF1 | 51575 | 218859_s_at | -1.6266 | 0.0333 | |
| GSE77861 | ESF1 | 51575 | 218859_s_at | 0.9757 | 0.0189 | |
| GSE97050 | ESF1 | 51575 | A_33_P3354955 | 0.0665 | 0.8945 | |
| SRP007169 | ESF1 | 51575 | RNAseq | 1.8993 | 0.0018 | |
| SRP008496 | ESF1 | 51575 | RNAseq | 2.8982 | 0.0000 | |
| SRP064894 | ESF1 | 51575 | RNAseq | 0.5737 | 0.0027 | |
| SRP133303 | ESF1 | 51575 | RNAseq | 0.4176 | 0.0000 | |
| SRP159526 | ESF1 | 51575 | RNAseq | 0.7363 | 0.0039 | |
| SRP193095 | ESF1 | 51575 | RNAseq | 0.2274 | 0.0662 | |
| SRP219564 | ESF1 | 51575 | RNAseq | 0.2765 | 0.2309 | |
| TCGA | ESF1 | 51575 | RNAseq | 0.0323 | 0.5860 |
Upregulated datasets: 2; Downregulated datasets: 1.
Survival by ESF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ESF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ESF1 | 51575 | 10 | 1 | 19 | |
| GSE20123 | ESF1 | 51575 | 10 | 1 | 19 | |
| GSE43470 | ESF1 | 51575 | 11 | 1 | 31 | |
| GSE46452 | ESF1 | 51575 | 26 | 1 | 32 | |
| GSE47630 | ESF1 | 51575 | 18 | 4 | 18 | |
| GSE54993 | ESF1 | 51575 | 0 | 15 | 55 | |
| GSE54994 | ESF1 | 51575 | 25 | 1 | 27 | |
| GSE60625 | ESF1 | 51575 | 0 | 0 | 11 | |
| GSE74703 | ESF1 | 51575 | 8 | 1 | 27 | |
| GSE74704 | ESF1 | 51575 | 5 | 1 | 14 | |
| TCGA | ESF1 | 51575 | 43 | 10 | 43 |
Total number of gains: 156; Total number of losses: 36; Total Number of normals: 296.
Somatic mutations of ESF1:
Generating mutation plots.
Highly correlated genes for ESF1:
Showing top 20/727 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ESF1 | KIAA0586 | 0.835378 | 3 | 0 | 3 |
| ESF1 | CCP110 | 0.808836 | 3 | 0 | 3 |
| ESF1 | SPRED1 | 0.767285 | 3 | 0 | 3 |
| ESF1 | KIN | 0.757537 | 3 | 0 | 3 |
| ESF1 | ACP1 | 0.750333 | 3 | 0 | 3 |
| ESF1 | FAM133B | 0.727057 | 3 | 0 | 3 |
| ESF1 | TMX3 | 0.726329 | 3 | 0 | 3 |
| ESF1 | PET117 | 0.720628 | 5 | 0 | 4 |
| ESF1 | ZSCAN29 | 0.718587 | 3 | 0 | 3 |
| ESF1 | ZC3H12C | 0.71853 | 3 | 0 | 3 |
| ESF1 | SPDYE3 | 0.718066 | 3 | 0 | 3 |
| ESF1 | TP53I13 | 0.715493 | 3 | 0 | 3 |
| ESF1 | MRPS5 | 0.715334 | 3 | 0 | 3 |
| ESF1 | ZBED6 | 0.712783 | 4 | 0 | 4 |
| ESF1 | CCDC112 | 0.71025 | 3 | 0 | 3 |
| ESF1 | LATS1 | 0.705017 | 4 | 0 | 4 |
| ESF1 | DHX33 | 0.704843 | 4 | 0 | 4 |
| ESF1 | PPIG | 0.704739 | 9 | 0 | 8 |
| ESF1 | ALG11 | 0.703391 | 3 | 0 | 3 |
| ESF1 | MYSM1 | 0.703195 | 3 | 0 | 3 |
For details and further investigation, click here
