| Full name: metal response element binding transcription factor 2 | Alias Symbol: M96|PCL2|TDRD19A | ||
| Type: protein-coding gene | Cytoband: 1p22.1 | ||
| Entrez ID: 22823 | HGNC ID: HGNC:29535 | Ensembl Gene: ENSG00000143033 | OMIM ID: 609882 |
| Drug and gene relationship at DGIdb | |||
Expression of MTF2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MTF2 | 22823 | 203345_s_at | 0.2442 | 0.2665 | |
| GSE20347 | MTF2 | 22823 | 203346_s_at | 0.6930 | 0.0000 | |
| GSE23400 | MTF2 | 22823 | 209705_at | 0.2070 | 0.0000 | |
| GSE26886 | MTF2 | 22823 | 203345_s_at | -0.1622 | 0.5257 | |
| GSE29001 | MTF2 | 22823 | 203345_s_at | 0.5513 | 0.0461 | |
| GSE38129 | MTF2 | 22823 | 203345_s_at | 0.3883 | 0.0022 | |
| GSE45670 | MTF2 | 22823 | 203345_s_at | 0.2904 | 0.0628 | |
| GSE53622 | MTF2 | 22823 | 37359 | 0.4933 | 0.0000 | |
| GSE53624 | MTF2 | 22823 | 37359 | 0.5573 | 0.0000 | |
| GSE63941 | MTF2 | 22823 | 203345_s_at | 2.6868 | 0.0002 | |
| GSE77861 | MTF2 | 22823 | 203345_s_at | 0.2327 | 0.3084 | |
| GSE97050 | MTF2 | 22823 | A_23_P46333 | 0.2955 | 0.4538 | |
| SRP007169 | MTF2 | 22823 | RNAseq | 1.2287 | 0.0022 | |
| SRP008496 | MTF2 | 22823 | RNAseq | 0.8173 | 0.0034 | |
| SRP064894 | MTF2 | 22823 | RNAseq | 0.4974 | 0.0170 | |
| SRP133303 | MTF2 | 22823 | RNAseq | 0.4353 | 0.0000 | |
| SRP159526 | MTF2 | 22823 | RNAseq | 0.1638 | 0.6938 | |
| SRP193095 | MTF2 | 22823 | RNAseq | 0.4091 | 0.0041 | |
| SRP219564 | MTF2 | 22823 | RNAseq | 0.2174 | 0.5205 | |
| TCGA | MTF2 | 22823 | RNAseq | 0.1264 | 0.0281 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by MTF2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MTF2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MTF2 | 22823 | 0 | 8 | 22 | |
| GSE20123 | MTF2 | 22823 | 0 | 8 | 22 | |
| GSE43470 | MTF2 | 22823 | 2 | 6 | 35 | |
| GSE46452 | MTF2 | 22823 | 1 | 1 | 57 | |
| GSE47630 | MTF2 | 22823 | 8 | 5 | 27 | |
| GSE54993 | MTF2 | 22823 | 0 | 1 | 69 | |
| GSE54994 | MTF2 | 22823 | 6 | 3 | 44 | |
| GSE60625 | MTF2 | 22823 | 0 | 0 | 11 | |
| GSE74703 | MTF2 | 22823 | 1 | 5 | 30 | |
| GSE74704 | MTF2 | 22823 | 0 | 5 | 15 | |
| TCGA | MTF2 | 22823 | 6 | 24 | 66 |
Total number of gains: 24; Total number of losses: 66; Total Number of normals: 398.
Somatic mutations of MTF2:
Generating mutation plots.
Highly correlated genes for MTF2:
Showing top 20/943 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MTF2 | SAAL1 | 0.697466 | 5 | 0 | 5 |
| MTF2 | CENPE | 0.684634 | 9 | 0 | 9 |
| MTF2 | UBE2T | 0.68187 | 7 | 0 | 7 |
| MTF2 | UCK2 | 0.674245 | 3 | 0 | 3 |
| MTF2 | SMYD5 | 0.671149 | 6 | 0 | 6 |
| MTF2 | NEK6 | 0.663836 | 3 | 0 | 3 |
| MTF2 | RPS27 | 0.6627 | 3 | 0 | 3 |
| MTF2 | MCM6 | 0.661624 | 11 | 0 | 10 |
| MTF2 | TIFAB | 0.655852 | 3 | 0 | 3 |
| MTF2 | CDKN3 | 0.655003 | 10 | 0 | 10 |
| MTF2 | CDCA2 | 0.649783 | 5 | 0 | 4 |
| MTF2 | FANCD2 | 0.648228 | 5 | 0 | 3 |
| MTF2 | ATAD2 | 0.647524 | 11 | 0 | 10 |
| MTF2 | IFFO2 | 0.646495 | 3 | 0 | 3 |
| MTF2 | CENPL | 0.645547 | 6 | 0 | 5 |
| MTF2 | BORA | 0.645505 | 9 | 0 | 8 |
| MTF2 | HOXA7 | 0.643893 | 3 | 0 | 3 |
| MTF2 | RFC3 | 0.643766 | 10 | 0 | 8 |
| MTF2 | CDCA7 | 0.643702 | 7 | 0 | 6 |
| MTF2 | CPSF7 | 0.64275 | 3 | 0 | 3 |
For details and further investigation, click here
