| Full name: activated leukocyte cell adhesion molecule | Alias Symbol: CD166|MEMD | ||
| Type: protein-coding gene | Cytoband: 3q13.11 | ||
| Entrez ID: 214 | HGNC ID: HGNC:400 | Ensembl Gene: ENSG00000170017 | OMIM ID: 601662 |
| Drug and gene relationship at DGIdb | |||
Expression of ALCAM:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ALCAM | 214 | 201952_at | 0.7245 | 0.5384 | |
| GSE20347 | ALCAM | 214 | 201952_at | 1.6959 | 0.0009 | |
| GSE23400 | ALCAM | 214 | 201952_at | 1.5065 | 0.0000 | |
| GSE26886 | ALCAM | 214 | 201952_at | 3.1098 | 0.0000 | |
| GSE29001 | ALCAM | 214 | 201952_at | 1.4342 | 0.0097 | |
| GSE38129 | ALCAM | 214 | 201952_at | 1.3442 | 0.0001 | |
| GSE45670 | ALCAM | 214 | 201952_at | 0.8083 | 0.1429 | |
| GSE53622 | ALCAM | 214 | 17171 | 1.0739 | 0.0000 | |
| GSE53624 | ALCAM | 214 | 17171 | 1.6119 | 0.0000 | |
| GSE63941 | ALCAM | 214 | 201952_at | -0.9827 | 0.3791 | |
| GSE77861 | ALCAM | 214 | 201952_at | 2.8013 | 0.0010 | |
| GSE97050 | ALCAM | 214 | A_33_P3713357 | 1.0191 | 0.1321 | |
| SRP007169 | ALCAM | 214 | RNAseq | 2.8639 | 0.0000 | |
| SRP008496 | ALCAM | 214 | RNAseq | 3.4195 | 0.0000 | |
| SRP064894 | ALCAM | 214 | RNAseq | 1.4889 | 0.0000 | |
| SRP133303 | ALCAM | 214 | RNAseq | 1.7596 | 0.0001 | |
| SRP159526 | ALCAM | 214 | RNAseq | 2.4695 | 0.0001 | |
| SRP193095 | ALCAM | 214 | RNAseq | 1.4090 | 0.0000 | |
| SRP219564 | ALCAM | 214 | RNAseq | 1.7147 | 0.0067 | |
| TCGA | ALCAM | 214 | RNAseq | -0.0740 | 0.5186 |
Upregulated datasets: 15; Downregulated datasets: 0.
Survival by ALCAM expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ALCAM:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ALCAM | 214 | 17 | 1 | 12 | |
| GSE20123 | ALCAM | 214 | 16 | 1 | 13 | |
| GSE43470 | ALCAM | 214 | 17 | 1 | 25 | |
| GSE46452 | ALCAM | 214 | 12 | 6 | 41 | |
| GSE47630 | ALCAM | 214 | 16 | 6 | 18 | |
| GSE54993 | ALCAM | 214 | 2 | 5 | 63 | |
| GSE54994 | ALCAM | 214 | 28 | 5 | 20 | |
| GSE60625 | ALCAM | 214 | 0 | 6 | 5 | |
| GSE74703 | ALCAM | 214 | 14 | 1 | 21 | |
| GSE74704 | ALCAM | 214 | 12 | 2 | 6 | |
| TCGA | ALCAM | 214 | 49 | 9 | 38 |
Total number of gains: 183; Total number of losses: 43; Total Number of normals: 262.
Somatic mutations of ALCAM:
Generating mutation plots.
Highly correlated genes for ALCAM:
Showing top 20/1297 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ALCAM | POLA1 | 0.802966 | 3 | 0 | 3 |
| ALCAM | SDHAF2 | 0.799728 | 3 | 0 | 3 |
| ALCAM | MPHOSPH6 | 0.789142 | 3 | 0 | 3 |
| ALCAM | ZNF597 | 0.781958 | 3 | 0 | 3 |
| ALCAM | RNF26 | 0.764722 | 3 | 0 | 3 |
| ALCAM | COMMD7 | 0.76295 | 3 | 0 | 3 |
| ALCAM | DFFA | 0.76138 | 3 | 0 | 3 |
| ALCAM | WDR81 | 0.76042 | 4 | 0 | 4 |
| ALCAM | EP400 | 0.756262 | 3 | 0 | 3 |
| ALCAM | METAP1D | 0.745795 | 3 | 0 | 3 |
| ALCAM | SMARCE1 | 0.743439 | 3 | 0 | 3 |
| ALCAM | SIX4 | 0.74118 | 8 | 0 | 8 |
| ALCAM | ZNF664 | 0.738818 | 3 | 0 | 3 |
| ALCAM | ZNF628 | 0.734801 | 3 | 0 | 3 |
| ALCAM | IQCK | 0.734151 | 3 | 0 | 3 |
| ALCAM | ZNF627 | 0.733983 | 3 | 0 | 3 |
| ALCAM | ZSCAN29 | 0.732051 | 3 | 0 | 3 |
| ALCAM | BAD | 0.73124 | 3 | 0 | 3 |
| ALCAM | ESCO1 | 0.730232 | 5 | 0 | 5 |
| ALCAM | SFR1 | 0.725926 | 3 | 0 | 3 |
For details and further investigation, click here
