| Full name: E1A binding protein p400 | Alias Symbol: CAGH32|KIAA1498|P400|KIAA1818|DKFZP434I225 | ||
| Type: protein-coding gene | Cytoband: 12q24.33 | ||
| Entrez ID: 57634 | HGNC ID: HGNC:11958 | Ensembl Gene: ENSG00000183495 | OMIM ID: 606265 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of EP400:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EP400 | 57634 | 212375_at | 0.2761 | 0.3477 | |
| GSE20347 | EP400 | 57634 | 212375_at | 0.0104 | 0.9408 | |
| GSE23400 | EP400 | 57634 | 212375_at | 0.0409 | 0.4425 | |
| GSE26886 | EP400 | 57634 | 212375_at | 0.1219 | 0.7046 | |
| GSE29001 | EP400 | 57634 | 212375_at | 0.1271 | 0.5911 | |
| GSE38129 | EP400 | 57634 | 212375_at | -0.0009 | 0.9945 | |
| GSE45670 | EP400 | 57634 | 212375_at | 0.0206 | 0.8785 | |
| GSE53622 | EP400 | 57634 | 38077 | 0.0600 | 0.3452 | |
| GSE53624 | EP400 | 57634 | 38077 | 0.1115 | 0.2616 | |
| GSE63941 | EP400 | 57634 | 212375_at | -0.5964 | 0.0089 | |
| GSE77861 | EP400 | 57634 | 212375_at | 0.3922 | 0.0783 | |
| GSE97050 | EP400 | 57634 | A_23_P253158 | -0.0433 | 0.8548 | |
| SRP007169 | EP400 | 57634 | RNAseq | 1.5655 | 0.0001 | |
| SRP008496 | EP400 | 57634 | RNAseq | 1.5698 | 0.0000 | |
| SRP064894 | EP400 | 57634 | RNAseq | 0.1575 | 0.4253 | |
| SRP133303 | EP400 | 57634 | RNAseq | 0.0299 | 0.7528 | |
| SRP159526 | EP400 | 57634 | RNAseq | 0.3653 | 0.1970 | |
| SRP193095 | EP400 | 57634 | RNAseq | 0.4171 | 0.0015 | |
| SRP219564 | EP400 | 57634 | RNAseq | 0.1279 | 0.6187 | |
| TCGA | EP400 | 57634 | RNAseq | 0.0330 | 0.4527 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by EP400 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EP400:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EP400 | 57634 | 4 | 5 | 21 | |
| GSE20123 | EP400 | 57634 | 4 | 5 | 21 | |
| GSE43470 | EP400 | 57634 | 3 | 3 | 37 | |
| GSE46452 | EP400 | 57634 | 8 | 3 | 48 | |
| GSE47630 | EP400 | 57634 | 9 | 3 | 28 | |
| GSE54993 | EP400 | 57634 | 0 | 6 | 64 | |
| GSE54994 | EP400 | 57634 | 4 | 8 | 41 | |
| GSE60625 | EP400 | 57634 | 0 | 0 | 11 | |
| GSE74703 | EP400 | 57634 | 2 | 3 | 31 | |
| GSE74704 | EP400 | 57634 | 2 | 3 | 15 | |
| TCGA | EP400 | 57634 | 23 | 15 | 58 |
Total number of gains: 59; Total number of losses: 54; Total Number of normals: 375.
Somatic mutations of EP400:
Generating mutation plots.
Highly correlated genes for EP400:
Showing top 20/656 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EP400 | TYW1 | 0.813144 | 3 | 0 | 3 |
| EP400 | ZNRF3 | 0.799427 | 3 | 0 | 3 |
| EP400 | SLC25A33 | 0.791321 | 3 | 0 | 3 |
| EP400 | EMILIN2 | 0.775487 | 3 | 0 | 3 |
| EP400 | PIF1 | 0.76882 | 3 | 0 | 3 |
| EP400 | UBR1 | 0.767289 | 3 | 0 | 3 |
| EP400 | TWSG1 | 0.766769 | 3 | 0 | 3 |
| EP400 | NOL9 | 0.764595 | 3 | 0 | 3 |
| EP400 | MED26 | 0.763119 | 3 | 0 | 3 |
| EP400 | ALCAM | 0.756262 | 3 | 0 | 3 |
| EP400 | RAD18 | 0.754054 | 3 | 0 | 3 |
| EP400 | SACS | 0.751678 | 3 | 0 | 3 |
| EP400 | NEK9 | 0.736462 | 3 | 0 | 3 |
| EP400 | TMTC1 | 0.734914 | 3 | 0 | 3 |
| EP400 | PANK4 | 0.730518 | 4 | 0 | 3 |
| EP400 | ZDHHC16 | 0.728772 | 3 | 0 | 3 |
| EP400 | MEF2D | 0.728578 | 3 | 0 | 3 |
| EP400 | ZXDC | 0.728487 | 3 | 0 | 3 |
| EP400 | CSTF2T | 0.727946 | 4 | 0 | 3 |
| EP400 | GRWD1 | 0.726335 | 3 | 0 | 3 |
For details and further investigation, click here
