| Full name: IQ motif containing K | Alias Symbol: MGC35048|FLJ36575 | ||
| Type: protein-coding gene | Cytoband: 16p12.3 | ||
| Entrez ID: 124152 | HGNC ID: HGNC:28556 | Ensembl Gene: ENSG00000174628 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of IQCK:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IQCK | 124152 | 213392_at | 0.2277 | 0.7703 | |
| GSE20347 | IQCK | 124152 | 213392_at | 0.2657 | 0.2882 | |
| GSE23400 | IQCK | 124152 | 215130_s_at | -0.0230 | 0.4482 | |
| GSE26886 | IQCK | 124152 | 213392_at | 1.1782 | 0.0000 | |
| GSE29001 | IQCK | 124152 | 215130_s_at | 0.0775 | 0.6367 | |
| GSE38129 | IQCK | 124152 | 213392_at | 0.2619 | 0.2056 | |
| GSE45670 | IQCK | 124152 | 213392_at | 0.0189 | 0.9547 | |
| GSE63941 | IQCK | 124152 | 213392_at | -0.7088 | 0.1363 | |
| GSE77861 | IQCK | 124152 | 215131_at | 0.1181 | 0.3120 | |
| GSE97050 | IQCK | 124152 | A_23_P324523 | 0.2536 | 0.2864 | |
| SRP007169 | IQCK | 124152 | RNAseq | 1.1996 | 0.0461 | |
| SRP008496 | IQCK | 124152 | RNAseq | 1.4096 | 0.0021 | |
| SRP064894 | IQCK | 124152 | RNAseq | 0.3195 | 0.1206 | |
| SRP133303 | IQCK | 124152 | RNAseq | 0.3771 | 0.0480 | |
| SRP159526 | IQCK | 124152 | RNAseq | 0.8582 | 0.0835 | |
| SRP193095 | IQCK | 124152 | RNAseq | 0.1829 | 0.3421 | |
| SRP219564 | IQCK | 124152 | RNAseq | 0.1076 | 0.6077 | |
| TCGA | IQCK | 124152 | RNAseq | -0.2112 | 0.0046 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by IQCK expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of IQCK:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IQCK | 124152 | 6 | 3 | 21 | |
| GSE20123 | IQCK | 124152 | 6 | 2 | 22 | |
| GSE43470 | IQCK | 124152 | 3 | 3 | 37 | |
| GSE46452 | IQCK | 124152 | 38 | 1 | 20 | |
| GSE47630 | IQCK | 124152 | 11 | 6 | 23 | |
| GSE54993 | IQCK | 124152 | 3 | 5 | 62 | |
| GSE54994 | IQCK | 124152 | 3 | 10 | 40 | |
| GSE60625 | IQCK | 124152 | 4 | 0 | 7 | |
| GSE74703 | IQCK | 124152 | 3 | 2 | 31 | |
| GSE74704 | IQCK | 124152 | 3 | 1 | 16 | |
| TCGA | IQCK | 124152 | 20 | 12 | 64 |
Total number of gains: 100; Total number of losses: 45; Total Number of normals: 343.
Somatic mutations of IQCK:
Generating mutation plots.
Highly correlated genes for IQCK:
Showing top 20/525 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IQCK | ATP11C | 0.766855 | 3 | 0 | 3 |
| IQCK | GZF1 | 0.759515 | 3 | 0 | 3 |
| IQCK | STK3 | 0.755399 | 3 | 0 | 3 |
| IQCK | PPP1R35 | 0.740199 | 3 | 0 | 3 |
| IQCK | ZCCHC7 | 0.739763 | 3 | 0 | 3 |
| IQCK | COMMD7 | 0.734611 | 3 | 0 | 3 |
| IQCK | ALCAM | 0.734151 | 3 | 0 | 3 |
| IQCK | MFHAS1 | 0.733951 | 3 | 0 | 3 |
| IQCK | PSMB4 | 0.731683 | 3 | 0 | 3 |
| IQCK | IFT52 | 0.729194 | 5 | 0 | 5 |
| IQCK | CIC | 0.728142 | 3 | 0 | 3 |
| IQCK | USP42 | 0.719482 | 3 | 0 | 3 |
| IQCK | XXYLT1 | 0.71785 | 3 | 0 | 3 |
| IQCK | TRMT12 | 0.714892 | 3 | 0 | 3 |
| IQCK | PLXNA1 | 0.713942 | 3 | 0 | 3 |
| IQCK | ATR | 0.707058 | 3 | 0 | 3 |
| IQCK | LYRM4 | 0.705404 | 5 | 0 | 5 |
| IQCK | CD69 | 0.697565 | 3 | 0 | 3 |
| IQCK | KCNS3 | 0.690411 | 3 | 0 | 3 |
| IQCK | APH1B | 0.688061 | 4 | 0 | 3 |
For details and further investigation, click here
