| Full name: M-phase phosphoprotein 6 | Alias Symbol: MPP6 | ||
| Type: protein-coding gene | Cytoband: 16q23.3 | ||
| Entrez ID: 10200 | HGNC ID: HGNC:7214 | Ensembl Gene: ENSG00000135698 | OMIM ID: 605500 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of MPHOSPH6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MPHOSPH6 | 10200 | 203740_at | 0.6731 | 0.3301 | |
| GSE20347 | MPHOSPH6 | 10200 | 203740_at | 0.4730 | 0.0018 | |
| GSE23400 | MPHOSPH6 | 10200 | 203740_at | 0.4143 | 0.0000 | |
| GSE26886 | MPHOSPH6 | 10200 | 203740_at | -0.1332 | 0.6061 | |
| GSE29001 | MPHOSPH6 | 10200 | 203740_at | 0.2464 | 0.3248 | |
| GSE38129 | MPHOSPH6 | 10200 | 203740_at | 0.6906 | 0.0000 | |
| GSE45670 | MPHOSPH6 | 10200 | 203740_at | 0.8672 | 0.0000 | |
| GSE53622 | MPHOSPH6 | 10200 | 1975 | 0.4691 | 0.0000 | |
| GSE53624 | MPHOSPH6 | 10200 | 1975 | 0.4499 | 0.0001 | |
| GSE63941 | MPHOSPH6 | 10200 | 203740_at | -0.6314 | 0.2436 | |
| GSE77861 | MPHOSPH6 | 10200 | 203740_at | 0.5378 | 0.0145 | |
| GSE97050 | MPHOSPH6 | 10200 | A_23_P140848 | 0.6564 | 0.1557 | |
| SRP007169 | MPHOSPH6 | 10200 | RNAseq | 0.5773 | 0.1584 | |
| SRP008496 | MPHOSPH6 | 10200 | RNAseq | 0.6266 | 0.0515 | |
| SRP064894 | MPHOSPH6 | 10200 | RNAseq | 0.2787 | 0.1990 | |
| SRP133303 | MPHOSPH6 | 10200 | RNAseq | 0.6612 | 0.0000 | |
| SRP159526 | MPHOSPH6 | 10200 | RNAseq | 0.0552 | 0.8694 | |
| SRP193095 | MPHOSPH6 | 10200 | RNAseq | 0.2837 | 0.0583 | |
| SRP219564 | MPHOSPH6 | 10200 | RNAseq | 0.1526 | 0.6610 | |
| TCGA | MPHOSPH6 | 10200 | RNAseq | 0.3184 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MPHOSPH6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MPHOSPH6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MPHOSPH6 | 10200 | 5 | 3 | 22 | |
| GSE20123 | MPHOSPH6 | 10200 | 5 | 2 | 23 | |
| GSE43470 | MPHOSPH6 | 10200 | 2 | 9 | 32 | |
| GSE46452 | MPHOSPH6 | 10200 | 37 | 2 | 20 | |
| GSE47630 | MPHOSPH6 | 10200 | 11 | 9 | 20 | |
| GSE54993 | MPHOSPH6 | 10200 | 2 | 4 | 64 | |
| GSE54994 | MPHOSPH6 | 10200 | 7 | 10 | 36 | |
| GSE60625 | MPHOSPH6 | 10200 | 4 | 0 | 7 | |
| GSE74703 | MPHOSPH6 | 10200 | 2 | 7 | 27 | |
| GSE74704 | MPHOSPH6 | 10200 | 3 | 2 | 15 | |
| TCGA | MPHOSPH6 | 10200 | 25 | 16 | 55 |
Total number of gains: 103; Total number of losses: 64; Total Number of normals: 321.
Somatic mutations of MPHOSPH6:
Generating mutation plots.
Highly correlated genes for MPHOSPH6:
Showing top 20/1367 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MPHOSPH6 | ALCAM | 0.789142 | 3 | 0 | 3 |
| MPHOSPH6 | IRF2BPL | 0.780221 | 3 | 0 | 3 |
| MPHOSPH6 | CDCA2 | 0.779697 | 4 | 0 | 4 |
| MPHOSPH6 | KREMEN1 | 0.770623 | 3 | 0 | 3 |
| MPHOSPH6 | ERCC8 | 0.75355 | 3 | 0 | 3 |
| MPHOSPH6 | NEDD1 | 0.753471 | 3 | 0 | 3 |
| MPHOSPH6 | SLC41A1 | 0.751151 | 3 | 0 | 3 |
| MPHOSPH6 | SNUPN | 0.747634 | 3 | 0 | 3 |
| MPHOSPH6 | SLC37A3 | 0.741139 | 3 | 0 | 3 |
| MPHOSPH6 | HDAC3 | 0.738163 | 3 | 0 | 3 |
| MPHOSPH6 | WDR54 | 0.737943 | 5 | 0 | 4 |
| MPHOSPH6 | AMMECR1L | 0.73401 | 4 | 0 | 4 |
| MPHOSPH6 | ERAP2 | 0.730967 | 3 | 0 | 3 |
| MPHOSPH6 | GOPC | 0.728571 | 3 | 0 | 3 |
| MPHOSPH6 | PFKM | 0.726519 | 3 | 0 | 3 |
| MPHOSPH6 | SPRED1 | 0.725109 | 4 | 0 | 3 |
| MPHOSPH6 | ZC3H12C | 0.724916 | 3 | 0 | 3 |
| MPHOSPH6 | CCT5 | 0.724347 | 8 | 0 | 7 |
| MPHOSPH6 | ZBTB9 | 0.720596 | 4 | 0 | 3 |
| MPHOSPH6 | XPR1 | 0.720456 | 5 | 0 | 4 |
For details and further investigation, click here
