| Full name: SWI5 dependent homologous recombination repair protein 1 | Alias Symbol: MEI5|bA373N18.1|FLJ41960 | ||
| Type: protein-coding gene | Cytoband: 10q25.1 | ||
| Entrez ID: 119392 | HGNC ID: HGNC:29574 | Ensembl Gene: ENSG00000156384 | OMIM ID: 616527 |
Screen Evidence:
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Expression of SFR1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SFR1 | 119392 | 236027_at | 0.4222 | 0.1408 | |
| GSE26886 | SFR1 | 119392 | 236027_at | 1.1067 | 0.0002 | |
| GSE45670 | SFR1 | 119392 | 236027_at | 0.1603 | 0.5406 | |
| GSE53622 | SFR1 | 119392 | 21087 | 0.5253 | 0.0000 | |
| GSE53624 | SFR1 | 119392 | 21087 | 0.4866 | 0.0000 | |
| GSE63941 | SFR1 | 119392 | 236027_at | 0.6730 | 0.2364 | |
| GSE77861 | SFR1 | 119392 | 236027_at | 0.2344 | 0.2795 | |
| GSE97050 | SFR1 | 119392 | A_23_P413193 | 0.3606 | 0.2813 | |
| SRP007169 | SFR1 | 119392 | RNAseq | -0.2965 | 0.5866 | |
| SRP008496 | SFR1 | 119392 | RNAseq | 0.2066 | 0.6040 | |
| SRP064894 | SFR1 | 119392 | RNAseq | 0.1652 | 0.3096 | |
| SRP133303 | SFR1 | 119392 | RNAseq | 0.4378 | 0.0033 | |
| SRP159526 | SFR1 | 119392 | RNAseq | 0.3692 | 0.3729 | |
| SRP193095 | SFR1 | 119392 | RNAseq | 0.6028 | 0.0000 | |
| SRP219564 | SFR1 | 119392 | RNAseq | 0.5675 | 0.0325 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by SFR1 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of SFR1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SFR1 | 119392 | 1 | 9 | 20 | |
| GSE20123 | SFR1 | 119392 | 1 | 8 | 21 | |
| GSE43470 | SFR1 | 119392 | 0 | 7 | 36 | |
| GSE46452 | SFR1 | 119392 | 0 | 11 | 48 | |
| GSE47630 | SFR1 | 119392 | 2 | 14 | 24 | |
| GSE54993 | SFR1 | 119392 | 8 | 0 | 62 | |
| GSE54994 | SFR1 | 119392 | 1 | 10 | 42 | |
| GSE60625 | SFR1 | 119392 | 0 | 0 | 11 | |
| GSE74703 | SFR1 | 119392 | 0 | 5 | 31 | |
| GSE74704 | SFR1 | 119392 | 0 | 4 | 16 | |
| TCGA | SFR1 | 119392 | 6 | 28 | 62 |
Total number of gains: 19; Total number of losses: 96; Total Number of normals: 373.
Somatic mutations of SFR1:
Generating mutation plots.
Highly correlated genes for SFR1:
Showing top 20/946 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SFR1 | PET117 | 0.827404 | 3 | 0 | 3 |
| SFR1 | METAP2 | 0.824236 | 3 | 0 | 3 |
| SFR1 | EDC4 | 0.823039 | 3 | 0 | 3 |
| SFR1 | RIOK1 | 0.819245 | 3 | 0 | 3 |
| SFR1 | CTU2 | 0.818933 | 3 | 0 | 3 |
| SFR1 | ALS2 | 0.818825 | 3 | 0 | 3 |
| SFR1 | MRPS17 | 0.816114 | 3 | 0 | 3 |
| SFR1 | UXS1 | 0.805339 | 3 | 0 | 3 |
| SFR1 | CCT6A | 0.795446 | 3 | 0 | 3 |
| SFR1 | MSTO1 | 0.789873 | 3 | 0 | 3 |
| SFR1 | GOSR2 | 0.780683 | 3 | 0 | 3 |
| SFR1 | ZCCHC2 | 0.778572 | 3 | 0 | 3 |
| SFR1 | MRPL9 | 0.77831 | 3 | 0 | 3 |
| SFR1 | MRPL55 | 0.775907 | 3 | 0 | 3 |
| SFR1 | PUF60 | 0.770749 | 3 | 0 | 3 |
| SFR1 | CEP152 | 0.770001 | 3 | 0 | 3 |
| SFR1 | TMEM132A | 0.764845 | 3 | 0 | 3 |
| SFR1 | UTP6 | 0.76326 | 3 | 0 | 3 |
| SFR1 | CPT1C | 0.763071 | 3 | 0 | 3 |
| SFR1 | NOL7 | 0.761804 | 3 | 0 | 3 |
For details and further investigation, click here
