| Full name: ALG11 alpha-1,2-mannosyltransferase | Alias Symbol: KIAA0266|CDG1P | ||
| Type: protein-coding gene | Cytoband: 13q14.3 | ||
| Entrez ID: 440138 | HGNC ID: HGNC:32456 | Ensembl Gene: ENSG00000253710 | OMIM ID: 613666 |
| Drug and gene relationship at DGIdb | |||
Expression of ALG11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | ALG11 | 440138 | 25638 | 0.8456 | 0.0000 | |
| GSE53624 | ALG11 | 440138 | 25638 | 0.5607 | 0.0000 | |
| GSE97050 | ALG11 | 440138 | A_33_P3230876 | -0.0746 | 0.7009 | |
| SRP007169 | ALG11 | 440138 | RNAseq | 1.2629 | 0.0061 | |
| SRP008496 | ALG11 | 440138 | RNAseq | 1.3388 | 0.0003 | |
| SRP064894 | ALG11 | 440138 | RNAseq | -0.0471 | 0.7872 | |
| SRP133303 | ALG11 | 440138 | RNAseq | -0.0531 | 0.6781 | |
| SRP159526 | ALG11 | 440138 | RNAseq | -0.4021 | 0.3583 | |
| SRP193095 | ALG11 | 440138 | RNAseq | -0.3219 | 0.0178 | |
| SRP219564 | ALG11 | 440138 | RNAseq | -0.1724 | 0.6004 | |
| TCGA | ALG11 | 440138 | RNAseq | -0.0744 | 0.6754 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by ALG11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ALG11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ALG11 | 440138 | 1 | 13 | 16 | |
| GSE20123 | ALG11 | 440138 | 1 | 12 | 17 | |
| GSE43470 | ALG11 | 440138 | 3 | 12 | 28 | |
| GSE46452 | ALG11 | 440138 | 0 | 32 | 27 | |
| GSE47630 | ALG11 | 440138 | 2 | 27 | 11 | |
| GSE54993 | ALG11 | 440138 | 12 | 2 | 56 | |
| GSE54994 | ALG11 | 440138 | 1 | 15 | 37 | |
| GSE60625 | ALG11 | 440138 | 0 | 3 | 8 | |
| GSE74703 | ALG11 | 440138 | 3 | 10 | 23 | |
| GSE74704 | ALG11 | 440138 | 0 | 9 | 11 | |
| TCGA | ALG11 | 440138 | 10 | 35 | 51 |
Total number of gains: 33; Total number of losses: 170; Total Number of normals: 285.
Somatic mutations of ALG11:
Generating mutation plots.
Highly correlated genes for ALG11:
Showing top 20/120 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ALG11 | ZNF445 | 0.925623 | 3 | 0 | 3 |
| ALG11 | ASB3 | 0.915437 | 3 | 0 | 3 |
| ALG11 | ZNF248 | 0.90499 | 3 | 0 | 3 |
| ALG11 | SZT2 | 0.900207 | 3 | 0 | 3 |
| ALG11 | GRIA4 | 0.874603 | 3 | 0 | 3 |
| ALG11 | REV3L | 0.867971 | 3 | 0 | 3 |
| ALG11 | NQO2 | 0.866076 | 3 | 0 | 3 |
| ALG11 | SLC38A6 | 0.861262 | 3 | 0 | 3 |
| ALG11 | RLIM | 0.844807 | 3 | 0 | 3 |
| ALG11 | CTPS2 | 0.839728 | 3 | 0 | 3 |
| ALG11 | OR2T33 | 0.838373 | 3 | 0 | 3 |
| ALG11 | CCDC154 | 0.835107 | 3 | 0 | 3 |
| ALG11 | TIGD1 | 0.834161 | 3 | 0 | 3 |
| ALG11 | LEPROTL1 | 0.829258 | 3 | 0 | 3 |
| ALG11 | FAM111B | 0.823638 | 3 | 0 | 3 |
| ALG11 | KRTAP12-2 | 0.821761 | 3 | 0 | 3 |
| ALG11 | CYP2B6 | 0.821219 | 3 | 0 | 3 |
| ALG11 | SLC26A5 | 0.819326 | 3 | 0 | 3 |
| ALG11 | CCDC144A | 0.813456 | 3 | 0 | 3 |
| ALG11 | CDH24 | 0.81062 | 3 | 0 | 3 |
For details and further investigation, click here
