| Full name: SZT2 subunit of KICSTOR complex | Alias Symbol: FLJ10387|SZT2B|RP11-506B15.1|FLJ34502|SZT2A | ||
| Type: protein-coding gene | Cytoband: 1p34.2 | ||
| Entrez ID: 23334 | HGNC ID: HGNC:29040 | Ensembl Gene: ENSG00000198198 | OMIM ID: 615463 |
| Drug and gene relationship at DGIdb | |||
Expression of SZT2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SZT2 | 23334 | 215364_s_at | 0.2600 | 0.6837 | |
| GSE20347 | SZT2 | 23334 | 215364_s_at | 0.0907 | 0.4916 | |
| GSE23400 | SZT2 | 23334 | 215364_s_at | 0.0745 | 0.1346 | |
| GSE26886 | SZT2 | 23334 | 215364_s_at | -0.1211 | 0.3830 | |
| GSE29001 | SZT2 | 23334 | 215364_s_at | -0.0650 | 0.8110 | |
| GSE38129 | SZT2 | 23334 | 215364_s_at | -0.0869 | 0.4105 | |
| GSE45670 | SZT2 | 23334 | 231249_at | 0.5320 | 0.0188 | |
| GSE53622 | SZT2 | 23334 | 27349 | 0.6316 | 0.0000 | |
| GSE53624 | SZT2 | 23334 | 27349 | 0.3674 | 0.0049 | |
| GSE63941 | SZT2 | 23334 | 231249_at | 0.1326 | 0.8495 | |
| GSE77861 | SZT2 | 23334 | 215364_s_at | 0.0744 | 0.7480 | |
| GSE97050 | SZT2 | 23334 | A_33_P3302373 | -0.0027 | 0.9938 | |
| SRP007169 | SZT2 | 23334 | RNAseq | 0.4516 | 0.2733 | |
| SRP008496 | SZT2 | 23334 | RNAseq | 0.1460 | 0.6523 | |
| SRP064894 | SZT2 | 23334 | RNAseq | 0.2486 | 0.1791 | |
| SRP133303 | SZT2 | 23334 | RNAseq | -0.1891 | 0.1342 | |
| SRP159526 | SZT2 | 23334 | RNAseq | 0.2845 | 0.5168 | |
| SRP193095 | SZT2 | 23334 | RNAseq | 0.4872 | 0.0018 | |
| SRP219564 | SZT2 | 23334 | RNAseq | 0.2001 | 0.5578 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SZT2 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of SZT2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SZT2 | 23334 | 4 | 3 | 23 | |
| GSE20123 | SZT2 | 23334 | 4 | 2 | 24 | |
| GSE43470 | SZT2 | 23334 | 7 | 2 | 34 | |
| GSE46452 | SZT2 | 23334 | 3 | 1 | 55 | |
| GSE47630 | SZT2 | 23334 | 9 | 3 | 28 | |
| GSE54993 | SZT2 | 23334 | 0 | 2 | 68 | |
| GSE54994 | SZT2 | 23334 | 13 | 2 | 38 | |
| GSE60625 | SZT2 | 23334 | 0 | 0 | 11 | |
| GSE74703 | SZT2 | 23334 | 6 | 1 | 29 | |
| GSE74704 | SZT2 | 23334 | 2 | 0 | 18 | |
| TCGA | SZT2 | 23334 | 13 | 17 | 66 |
Total number of gains: 61; Total number of losses: 33; Total Number of normals: 394.
Somatic mutations of SZT2:
Generating mutation plots.
Highly correlated genes for SZT2:
Showing top 20/401 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SZT2 | ALG11 | 0.900207 | 3 | 0 | 3 |
| SZT2 | CTPS2 | 0.882792 | 3 | 0 | 3 |
| SZT2 | OR2T33 | 0.864114 | 3 | 0 | 3 |
| SZT2 | USP2-AS1 | 0.849742 | 3 | 0 | 3 |
| SZT2 | KRTAP12-2 | 0.840476 | 3 | 0 | 3 |
| SZT2 | ZNF445 | 0.839474 | 4 | 0 | 4 |
| SZT2 | CCIN | 0.835563 | 4 | 0 | 4 |
| SZT2 | SLC26A5 | 0.830881 | 3 | 0 | 3 |
| SZT2 | OR2AT4 | 0.828488 | 3 | 0 | 3 |
| SZT2 | ASB3 | 0.816345 | 3 | 0 | 3 |
| SZT2 | SPEG | 0.811563 | 3 | 0 | 3 |
| SZT2 | ARL17A | 0.806855 | 3 | 0 | 3 |
| SZT2 | NPFF | 0.802531 | 3 | 0 | 3 |
| SZT2 | CYHR1 | 0.782381 | 3 | 0 | 3 |
| SZT2 | ZC3H18 | 0.781474 | 3 | 0 | 3 |
| SZT2 | SF3A2 | 0.777415 | 4 | 0 | 4 |
| SZT2 | CDH24 | 0.772027 | 4 | 0 | 3 |
| SZT2 | GRIA4 | 0.771332 | 4 | 0 | 3 |
| SZT2 | PRR12 | 0.76638 | 3 | 0 | 3 |
| SZT2 | OR1L6 | 0.754329 | 3 | 0 | 3 |
For details and further investigation, click here
