| Full name: family with sequence similarity 111 member B | Alias Symbol: CANP | ||
| Type: protein-coding gene | Cytoband: 11q12.1 | ||
| Entrez ID: 374393 | HGNC ID: HGNC:24200 | Ensembl Gene: ENSG00000189057 | OMIM ID: 615584 |
| Drug and gene relationship at DGIdb | |||
Expression of FAM111B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM111B | 374393 | 1557128_at | 0.0873 | 0.7745 | |
| GSE26886 | FAM111B | 374393 | 1557128_at | 0.3249 | 0.0492 | |
| GSE45670 | FAM111B | 374393 | 1557128_at | 0.8088 | 0.0032 | |
| GSE53622 | FAM111B | 374393 | 63573 | 0.6669 | 0.0000 | |
| GSE53624 | FAM111B | 374393 | 63573 | 0.7771 | 0.0000 | |
| GSE63941 | FAM111B | 374393 | 1557128_at | 1.2630 | 0.0111 | |
| GSE77861 | FAM111B | 374393 | 1557128_at | 0.2542 | 0.2551 | |
| GSE97050 | FAM111B | 374393 | A_33_P3270657 | 0.2166 | 0.4464 | |
| SRP007169 | FAM111B | 374393 | RNAseq | 1.7992 | 0.0047 | |
| SRP008496 | FAM111B | 374393 | RNAseq | 1.4504 | 0.0032 | |
| SRP064894 | FAM111B | 374393 | RNAseq | 0.9270 | 0.0072 | |
| SRP133303 | FAM111B | 374393 | RNAseq | 0.7223 | 0.0000 | |
| SRP159526 | FAM111B | 374393 | RNAseq | 1.0494 | 0.0273 | |
| SRP193095 | FAM111B | 374393 | RNAseq | 0.4991 | 0.0000 | |
| SRP219564 | FAM111B | 374393 | RNAseq | 0.7107 | 0.2466 | |
| TCGA | FAM111B | 374393 | RNAseq | 0.9639 | 0.0000 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by FAM111B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAM111B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM111B | 374393 | 1 | 5 | 24 | |
| GSE20123 | FAM111B | 374393 | 1 | 5 | 24 | |
| GSE43470 | FAM111B | 374393 | 1 | 5 | 37 | |
| GSE46452 | FAM111B | 374393 | 10 | 4 | 45 | |
| GSE47630 | FAM111B | 374393 | 3 | 8 | 29 | |
| GSE54993 | FAM111B | 374393 | 3 | 0 | 67 | |
| GSE54994 | FAM111B | 374393 | 5 | 6 | 42 | |
| GSE60625 | FAM111B | 374393 | 0 | 3 | 8 | |
| GSE74703 | FAM111B | 374393 | 1 | 3 | 32 | |
| GSE74704 | FAM111B | 374393 | 1 | 4 | 15 | |
| TCGA | FAM111B | 374393 | 14 | 10 | 72 |
Total number of gains: 40; Total number of losses: 53; Total Number of normals: 395.
Somatic mutations of FAM111B:
Generating mutation plots.
Highly correlated genes for FAM111B:
Showing top 20/459 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM111B | ALG11 | 0.823638 | 3 | 0 | 3 |
| FAM111B | ASB7 | 0.798044 | 3 | 0 | 3 |
| FAM111B | ASB3 | 0.77766 | 3 | 0 | 3 |
| FAM111B | FCHSD2 | 0.773395 | 3 | 0 | 3 |
| FAM111B | KDM1B | 0.768637 | 3 | 0 | 3 |
| FAM111B | RNF26 | 0.760129 | 3 | 0 | 3 |
| FAM111B | USP2-AS1 | 0.759256 | 3 | 0 | 3 |
| FAM111B | LGALS8 | 0.745912 | 3 | 0 | 3 |
| FAM111B | TAS2R43 | 0.745809 | 3 | 0 | 3 |
| FAM111B | KLF14 | 0.74254 | 3 | 0 | 3 |
| FAM111B | PMM2 | 0.742303 | 3 | 0 | 3 |
| FAM111B | NPRL3 | 0.741753 | 3 | 0 | 3 |
| FAM111B | SLCO3A1 | 0.730387 | 3 | 0 | 3 |
| FAM111B | SRGAP1 | 0.725743 | 3 | 0 | 3 |
| FAM111B | SLC16A5 | 0.722731 | 3 | 0 | 3 |
| FAM111B | SMC2 | 0.721009 | 4 | 0 | 4 |
| FAM111B | SLC26A5 | 0.720575 | 3 | 0 | 3 |
| FAM111B | NARS2 | 0.716814 | 3 | 0 | 3 |
| FAM111B | IKBKG | 0.711378 | 3 | 0 | 3 |
| FAM111B | USP17L2 | 0.709287 | 3 | 0 | 3 |
For details and further investigation, click here
