| Full name: leptin receptor overlapping transcript like 1 | Alias Symbol: my047|Vps55 | ||
| Type: protein-coding gene | Cytoband: 8p12 | ||
| Entrez ID: 23484 | HGNC ID: HGNC:6555 | Ensembl Gene: ENSG00000104660 | OMIM ID: 607338 |
| Drug and gene relationship at DGIdb | |||
Expression of LEPROTL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LEPROTL1 | 23484 | 202595_s_at | 0.4474 | 0.5031 | |
| GSE20347 | LEPROTL1 | 23484 | 202595_s_at | 0.5783 | 0.0036 | |
| GSE23400 | LEPROTL1 | 23484 | 202595_s_at | 0.5934 | 0.0000 | |
| GSE26886 | LEPROTL1 | 23484 | 202595_s_at | 0.6623 | 0.0005 | |
| GSE29001 | LEPROTL1 | 23484 | 202595_s_at | 0.5298 | 0.0616 | |
| GSE38129 | LEPROTL1 | 23484 | 202594_at | 0.1964 | 0.1855 | |
| GSE45670 | LEPROTL1 | 23484 | 202594_at | 0.2991 | 0.0726 | |
| GSE53622 | LEPROTL1 | 23484 | 42949 | 0.5660 | 0.0001 | |
| GSE53624 | LEPROTL1 | 23484 | 42949 | 0.3958 | 0.0002 | |
| GSE63941 | LEPROTL1 | 23484 | 202595_s_at | -0.2154 | 0.5522 | |
| GSE77861 | LEPROTL1 | 23484 | 202595_s_at | 0.7813 | 0.0006 | |
| GSE97050 | LEPROTL1 | 23484 | A_33_P3252206 | -0.0133 | 0.9676 | |
| SRP007169 | LEPROTL1 | 23484 | RNAseq | 0.3220 | 0.4348 | |
| SRP008496 | LEPROTL1 | 23484 | RNAseq | 0.2761 | 0.3114 | |
| SRP064894 | LEPROTL1 | 23484 | RNAseq | 0.5555 | 0.0000 | |
| SRP133303 | LEPROTL1 | 23484 | RNAseq | -0.0206 | 0.8548 | |
| SRP159526 | LEPROTL1 | 23484 | RNAseq | 0.1654 | 0.3880 | |
| SRP193095 | LEPROTL1 | 23484 | RNAseq | 0.1470 | 0.0940 | |
| SRP219564 | LEPROTL1 | 23484 | RNAseq | 0.1367 | 0.6167 | |
| TCGA | LEPROTL1 | 23484 | RNAseq | -0.0343 | 0.5100 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LEPROTL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LEPROTL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LEPROTL1 | 23484 | 4 | 10 | 16 | |
| GSE20123 | LEPROTL1 | 23484 | 4 | 10 | 16 | |
| GSE43470 | LEPROTL1 | 23484 | 4 | 7 | 32 | |
| GSE46452 | LEPROTL1 | 23484 | 13 | 13 | 33 | |
| GSE47630 | LEPROTL1 | 23484 | 10 | 8 | 22 | |
| GSE54993 | LEPROTL1 | 23484 | 2 | 15 | 53 | |
| GSE54994 | LEPROTL1 | 23484 | 10 | 15 | 28 | |
| GSE60625 | LEPROTL1 | 23484 | 3 | 0 | 8 | |
| GSE74703 | LEPROTL1 | 23484 | 4 | 6 | 26 | |
| GSE74704 | LEPROTL1 | 23484 | 3 | 7 | 10 | |
| TCGA | LEPROTL1 | 23484 | 17 | 41 | 38 |
Total number of gains: 74; Total number of losses: 132; Total Number of normals: 282.
Somatic mutations of LEPROTL1:
Generating mutation plots.
Highly correlated genes for LEPROTL1:
Showing top 20/964 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LEPROTL1 | ALG11 | 0.829258 | 3 | 0 | 3 |
| LEPROTL1 | ZSCAN30 | 0.786455 | 3 | 0 | 3 |
| LEPROTL1 | OR1L6 | 0.780621 | 3 | 0 | 3 |
| LEPROTL1 | KCNQ1OT1 | 0.780619 | 3 | 0 | 3 |
| LEPROTL1 | ASB3 | 0.775697 | 3 | 0 | 3 |
| LEPROTL1 | RGPD6 | 0.750943 | 3 | 0 | 3 |
| LEPROTL1 | KREMEN1 | 0.750045 | 3 | 0 | 3 |
| LEPROTL1 | CASC4 | 0.737824 | 3 | 0 | 3 |
| LEPROTL1 | CEBPZ | 0.729968 | 3 | 0 | 3 |
| LEPROTL1 | FAM220A | 0.728665 | 3 | 0 | 3 |
| LEPROTL1 | OR2AT4 | 0.724586 | 3 | 0 | 3 |
| LEPROTL1 | SLAMF9 | 0.722554 | 5 | 0 | 5 |
| LEPROTL1 | TPM3 | 0.719362 | 3 | 0 | 3 |
| LEPROTL1 | VWA5B1 | 0.718189 | 4 | 0 | 3 |
| LEPROTL1 | DUS3L | 0.715643 | 3 | 0 | 3 |
| LEPROTL1 | ADCY3 | 0.710294 | 5 | 0 | 5 |
| LEPROTL1 | SLC26A5 | 0.708185 | 3 | 0 | 3 |
| LEPROTL1 | FAM111B | 0.707371 | 4 | 0 | 3 |
| LEPROTL1 | USP17L2 | 0.706469 | 3 | 0 | 3 |
| LEPROTL1 | KLHL5 | 0.704248 | 3 | 0 | 3 |
For details and further investigation, click here
