| Full name: solute carrier family 38 member 6 | Alias Symbol: NAT-1 | ||
| Type: protein-coding gene | Cytoband: 14q23.1 | ||
| Entrez ID: 145389 | HGNC ID: HGNC:19863 | Ensembl Gene: ENSG00000139974 | OMIM ID: 616518 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC38A6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC38A6 | 145389 | 214830_at | 1.2200 | 0.0560 | |
| GSE20347 | SLC38A6 | 145389 | 214830_at | 1.7905 | 0.0000 | |
| GSE23400 | SLC38A6 | 145389 | 214830_at | 1.1324 | 0.0000 | |
| GSE26886 | SLC38A6 | 145389 | 214830_at | 1.2825 | 0.0000 | |
| GSE29001 | SLC38A6 | 145389 | 214830_at | 1.5643 | 0.0000 | |
| GSE38129 | SLC38A6 | 145389 | 214830_at | 1.6346 | 0.0000 | |
| GSE45670 | SLC38A6 | 145389 | 214830_at | 1.0556 | 0.0016 | |
| GSE53622 | SLC38A6 | 145389 | 49080 | 0.4652 | 0.0000 | |
| GSE53624 | SLC38A6 | 145389 | 49080 | 0.5446 | 0.0000 | |
| GSE63941 | SLC38A6 | 145389 | 214830_at | -1.7376 | 0.0130 | |
| GSE77861 | SLC38A6 | 145389 | 214830_at | 1.5400 | 0.0155 | |
| GSE97050 | SLC38A6 | 145389 | A_33_P3404954 | -0.0106 | 0.9705 | |
| SRP007169 | SLC38A6 | 145389 | RNAseq | 1.7322 | 0.0006 | |
| SRP008496 | SLC38A6 | 145389 | RNAseq | 1.6176 | 0.0000 | |
| SRP064894 | SLC38A6 | 145389 | RNAseq | 1.5737 | 0.0000 | |
| SRP133303 | SLC38A6 | 145389 | RNAseq | 1.1977 | 0.0000 | |
| SRP159526 | SLC38A6 | 145389 | RNAseq | 1.3186 | 0.0000 | |
| SRP193095 | SLC38A6 | 145389 | RNAseq | 1.1058 | 0.0000 | |
| SRP219564 | SLC38A6 | 145389 | RNAseq | 1.2605 | 0.0028 | |
| TCGA | SLC38A6 | 145389 | RNAseq | 0.4600 | 0.0000 |
Upregulated datasets: 14; Downregulated datasets: 1.
Survival by SLC38A6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC38A6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC38A6 | 145389 | 9 | 3 | 18 | |
| GSE20123 | SLC38A6 | 145389 | 8 | 3 | 19 | |
| GSE43470 | SLC38A6 | 145389 | 8 | 2 | 33 | |
| GSE46452 | SLC38A6 | 145389 | 16 | 3 | 40 | |
| GSE47630 | SLC38A6 | 145389 | 11 | 9 | 20 | |
| GSE54993 | SLC38A6 | 145389 | 3 | 9 | 58 | |
| GSE54994 | SLC38A6 | 145389 | 19 | 4 | 30 | |
| GSE60625 | SLC38A6 | 145389 | 0 | 2 | 9 | |
| GSE74703 | SLC38A6 | 145389 | 7 | 2 | 27 | |
| GSE74704 | SLC38A6 | 145389 | 4 | 2 | 14 | |
| TCGA | SLC38A6 | 145389 | 32 | 14 | 50 |
Total number of gains: 117; Total number of losses: 53; Total Number of normals: 318.
Somatic mutations of SLC38A6:
Generating mutation plots.
Highly correlated genes for SLC38A6:
Showing top 20/1528 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC38A6 | ALG11 | 0.861262 | 3 | 0 | 3 |
| SLC38A6 | ATP11C | 0.842434 | 3 | 0 | 3 |
| SLC38A6 | ASB3 | 0.824146 | 3 | 0 | 3 |
| SLC38A6 | G2E3 | 0.796084 | 4 | 0 | 4 |
| SLC38A6 | GALNT18 | 0.782532 | 3 | 0 | 3 |
| SLC38A6 | NEK3 | 0.779557 | 3 | 0 | 3 |
| SLC38A6 | OR1L6 | 0.778909 | 3 | 0 | 3 |
| SLC38A6 | NEDD1 | 0.775625 | 5 | 0 | 5 |
| SLC38A6 | SLC26A5 | 0.773199 | 3 | 0 | 3 |
| SLC38A6 | C12orf57 | 0.769723 | 3 | 0 | 3 |
| SLC38A6 | FZD6 | 0.766374 | 9 | 0 | 9 |
| SLC38A6 | TAS2R43 | 0.765997 | 3 | 0 | 3 |
| SLC38A6 | DHX40 | 0.76434 | 3 | 0 | 3 |
| SLC38A6 | MNAT1 | 0.764053 | 11 | 0 | 10 |
| SLC38A6 | CENPL | 0.75988 | 5 | 0 | 5 |
| SLC38A6 | C1orf131 | 0.756133 | 5 | 0 | 5 |
| SLC38A6 | GNPNAT1 | 0.753125 | 3 | 0 | 3 |
| SLC38A6 | KRTAP12-2 | 0.750374 | 3 | 0 | 3 |
| SLC38A6 | WDYHV1 | 0.747713 | 9 | 0 | 9 |
| SLC38A6 | PSMB4 | 0.747004 | 9 | 0 | 9 |
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