| Full name: amphiphysin | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 7p14.1 | ||
| Entrez ID: 273 | HGNC ID: HGNC:471 | Ensembl Gene: ENSG00000078053 | OMIM ID: 600418 |
| Drug and gene relationship at DGIdb | |||
AMPH involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04666 | Fc gamma R-mediated phagocytosis |
Expression of AMPH:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AMPH | 273 | 205257_s_at | -0.5642 | 0.4383 | |
| GSE20347 | AMPH | 273 | 205257_s_at | 0.1362 | 0.2126 | |
| GSE23400 | AMPH | 273 | 205257_s_at | 0.0098 | 0.8295 | |
| GSE26886 | AMPH | 273 | 205257_s_at | 0.2472 | 0.5892 | |
| GSE29001 | AMPH | 273 | 205257_s_at | -0.0213 | 0.9290 | |
| GSE38129 | AMPH | 273 | 205257_s_at | -0.4211 | 0.0363 | |
| GSE45670 | AMPH | 273 | 205257_s_at | -0.7962 | 0.0001 | |
| GSE53622 | AMPH | 273 | 63284 | -0.1271 | 0.5526 | |
| GSE53624 | AMPH | 273 | 63284 | -0.0118 | 0.9566 | |
| GSE63941 | AMPH | 273 | 205257_s_at | -3.1804 | 0.0003 | |
| GSE77861 | AMPH | 273 | 205257_s_at | -0.0569 | 0.5257 | |
| SRP007169 | AMPH | 273 | RNAseq | 2.3139 | 0.0167 | |
| SRP064894 | AMPH | 273 | RNAseq | 0.0427 | 0.8965 | |
| SRP133303 | AMPH | 273 | RNAseq | 0.2536 | 0.3769 | |
| SRP159526 | AMPH | 273 | RNAseq | -0.2451 | 0.6071 | |
| SRP219564 | AMPH | 273 | RNAseq | -0.6357 | 0.3278 | |
| TCGA | AMPH | 273 | RNAseq | -0.4153 | 0.1317 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by AMPH expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AMPH:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AMPH | 273 | 15 | 0 | 15 | |
| GSE20123 | AMPH | 273 | 14 | 0 | 16 | |
| GSE43470 | AMPH | 273 | 4 | 0 | 39 | |
| GSE46452 | AMPH | 273 | 11 | 1 | 47 | |
| GSE47630 | AMPH | 273 | 8 | 1 | 31 | |
| GSE54993 | AMPH | 273 | 0 | 7 | 63 | |
| GSE54994 | AMPH | 273 | 18 | 3 | 32 | |
| GSE60625 | AMPH | 273 | 0 | 0 | 11 | |
| GSE74703 | AMPH | 273 | 4 | 0 | 32 | |
| GSE74704 | AMPH | 273 | 8 | 0 | 12 | |
| TCGA | AMPH | 273 | 53 | 6 | 37 |
Total number of gains: 135; Total number of losses: 18; Total Number of normals: 335.
Somatic mutations of AMPH:
Generating mutation plots.
Highly correlated genes for AMPH:
Showing top 20/603 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AMPH | FIBIN | 0.79774 | 3 | 0 | 3 |
| AMPH | LRRK2 | 0.752196 | 3 | 0 | 3 |
| AMPH | INMT | 0.739522 | 3 | 0 | 3 |
| AMPH | PABPC5 | 0.737746 | 5 | 0 | 5 |
| AMPH | CNTN4 | 0.729386 | 3 | 0 | 3 |
| AMPH | DNM3OS | 0.727574 | 3 | 0 | 3 |
| AMPH | CCDC69 | 0.723041 | 4 | 0 | 4 |
| AMPH | C11orf96 | 0.711901 | 3 | 0 | 3 |
| AMPH | GALNT15 | 0.71179 | 4 | 0 | 4 |
| AMPH | NAV3 | 0.710768 | 3 | 0 | 3 |
| AMPH | LAMA2 | 0.710397 | 7 | 0 | 6 |
| AMPH | VSTM4 | 0.709249 | 7 | 0 | 7 |
| AMPH | CNRIP1 | 0.704881 | 6 | 0 | 5 |
| AMPH | TCEAL7 | 0.699136 | 5 | 0 | 5 |
| AMPH | SGCD | 0.698985 | 7 | 0 | 7 |
| AMPH | MAGI2-AS3 | 0.693898 | 5 | 0 | 4 |
| AMPH | FNBP1 | 0.692784 | 4 | 0 | 4 |
| AMPH | ZCCHC24 | 0.691335 | 7 | 0 | 5 |
| AMPH | TMEM71 | 0.689543 | 4 | 0 | 4 |
| AMPH | DCLK1 | 0.689217 | 4 | 0 | 4 |
For details and further investigation, click here
