| Full name: solute carrier family 35 member B3 | Alias Symbol: CGI-19|dJ453H5.1|PAPST2 | ||
| Type: protein-coding gene | Cytoband: 6p24.3 | ||
| Entrez ID: 51000 | HGNC ID: HGNC:21601 | Ensembl Gene: ENSG00000124786 | OMIM ID: 610845 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC35B3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC35B3 | 51000 | 222691_at | 0.3724 | 0.5105 | |
| GSE26886 | SLC35B3 | 51000 | 222691_at | -0.7813 | 0.0041 | |
| GSE45670 | SLC35B3 | 51000 | 222691_at | 0.2650 | 0.1583 | |
| GSE53622 | SLC35B3 | 51000 | 63456 | 0.0279 | 0.7264 | |
| GSE53624 | SLC35B3 | 51000 | 72690 | 0.0768 | 0.1962 | |
| GSE63941 | SLC35B3 | 51000 | 222691_at | -1.5370 | 0.0094 | |
| GSE77861 | SLC35B3 | 51000 | 222691_at | -0.1103 | 0.8332 | |
| GSE97050 | SLC35B3 | 51000 | A_23_P145463 | 0.2962 | 0.3311 | |
| SRP007169 | SLC35B3 | 51000 | RNAseq | 0.2606 | 0.5397 | |
| SRP008496 | SLC35B3 | 51000 | RNAseq | 0.3072 | 0.2618 | |
| SRP064894 | SLC35B3 | 51000 | RNAseq | 0.1948 | 0.2736 | |
| SRP133303 | SLC35B3 | 51000 | RNAseq | 0.2573 | 0.0730 | |
| SRP159526 | SLC35B3 | 51000 | RNAseq | 0.4159 | 0.0588 | |
| SRP193095 | SLC35B3 | 51000 | RNAseq | -0.5062 | 0.0002 | |
| SRP219564 | SLC35B3 | 51000 | RNAseq | -0.0836 | 0.7039 | |
| TCGA | SLC35B3 | 51000 | RNAseq | -0.2164 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by SLC35B3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC35B3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC35B3 | 51000 | 4 | 6 | 20 | |
| GSE20123 | SLC35B3 | 51000 | 3 | 6 | 21 | |
| GSE43470 | SLC35B3 | 51000 | 8 | 2 | 33 | |
| GSE46452 | SLC35B3 | 51000 | 1 | 10 | 48 | |
| GSE47630 | SLC35B3 | 51000 | 7 | 8 | 25 | |
| GSE54993 | SLC35B3 | 51000 | 1 | 1 | 68 | |
| GSE54994 | SLC35B3 | 51000 | 10 | 3 | 40 | |
| GSE60625 | SLC35B3 | 51000 | 0 | 1 | 10 | |
| GSE74703 | SLC35B3 | 51000 | 7 | 2 | 27 | |
| GSE74704 | SLC35B3 | 51000 | 2 | 2 | 16 | |
| TCGA | SLC35B3 | 51000 | 15 | 29 | 52 |
Total number of gains: 58; Total number of losses: 70; Total Number of normals: 360.
Somatic mutations of SLC35B3:
Generating mutation plots.
Highly correlated genes for SLC35B3:
Showing top 20/508 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC35B3 | TRIM8 | 0.820531 | 3 | 0 | 3 |
| SLC35B3 | FAM149B1 | 0.817624 | 3 | 0 | 3 |
| SLC35B3 | RRP36 | 0.814664 | 3 | 0 | 3 |
| SLC35B3 | ARFGAP2 | 0.801329 | 3 | 0 | 3 |
| SLC35B3 | PRPF4B | 0.793306 | 4 | 0 | 4 |
| SLC35B3 | VAMP5 | 0.787541 | 3 | 0 | 3 |
| SLC35B3 | MPHOSPH9 | 0.780245 | 3 | 0 | 3 |
| SLC35B3 | CNOT4 | 0.779904 | 3 | 0 | 3 |
| SLC35B3 | ARID1B | 0.777428 | 3 | 0 | 3 |
| SLC35B3 | ZNF607 | 0.777258 | 3 | 0 | 3 |
| SLC35B3 | MON1A | 0.773736 | 3 | 0 | 3 |
| SLC35B3 | GALNT11 | 0.766225 | 3 | 0 | 3 |
| SLC35B3 | EGLN1 | 0.76453 | 3 | 0 | 3 |
| SLC35B3 | EI24 | 0.762361 | 4 | 0 | 4 |
| SLC35B3 | USP4 | 0.761295 | 3 | 0 | 3 |
| SLC35B3 | ETV6 | 0.75889 | 3 | 0 | 3 |
| SLC35B3 | PCNT | 0.757466 | 3 | 0 | 3 |
| SLC35B3 | SLC35A2 | 0.757284 | 3 | 0 | 3 |
| SLC35B3 | SMPD1 | 0.756728 | 3 | 0 | 3 |
| SLC35B3 | ZNF649 | 0.755597 | 3 | 0 | 3 |
For details and further investigation, click here
