NIPAL3

 

Full name: NIPA like domain containing 3 Alias Symbol: DJ462O23.2
Type: protein-coding gene Cytoband: 1p36.11
Entrez ID: 57185 HGNC ID: HGNC:25233 Ensembl Gene: ENSG00000001461 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of NIPAL3:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 NIPAL3 57185 225876_at 0.4839 0.4826
GSE20347 NIPAL3 57185 214579_at -0.3535 0.0004
GSE23400 NIPAL3 57185 214579_at -0.2282 0.0000
GSE26886 NIPAL3 57185 225876_at -0.9453 0.0079
GSE29001 NIPAL3 57185 214579_at -0.2248 0.0848
GSE38129 NIPAL3 57185 214579_at -0.2672 0.0051
GSE45670 NIPAL3 57185 225876_at 0.1295 0.5726
GSE53622 NIPAL3 57185 86367 -0.5885 0.0000
GSE53624 NIPAL3 57185 86367 -0.3818 0.0000
GSE63941 NIPAL3 57185 225876_at -2.1395 0.0031
GSE77861 NIPAL3 57185 214579_at -0.2015 0.0769
GSE97050 NIPAL3 57185 A_24_P45367 -0.5707 0.1022
SRP007169 NIPAL3 57185 RNAseq -2.3017 0.0000
SRP008496 NIPAL3 57185 RNAseq -1.7262 0.0000
SRP064894 NIPAL3 57185 RNAseq -1.2065 0.0000
SRP133303 NIPAL3 57185 RNAseq -0.2397 0.1286
SRP159526 NIPAL3 57185 RNAseq -0.5507 0.0692
SRP193095 NIPAL3 57185 RNAseq -0.4443 0.0000
SRP219564 NIPAL3 57185 RNAseq -0.9855 0.0279
TCGA NIPAL3 57185 RNAseq -0.2526 0.0000

Upregulated datasets: 0; Downregulated datasets: 4.  


 

Survival by NIPAL3 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of NIPAL3:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 NIPAL3 57185 0 5 25
GSE20123 NIPAL3 57185 0 4 26
GSE43470 NIPAL3 57185 2 6 35
GSE46452 NIPAL3 57185 5 1 53
GSE47630 NIPAL3 57185 8 3 29
GSE54993 NIPAL3 57185 2 1 67
GSE54994 NIPAL3 57185 11 4 38
GSE60625 NIPAL3 57185 0 0 11
GSE74703 NIPAL3 57185 1 4 31
GSE74704 NIPAL3 57185 0 0 20
TCGA NIPAL3 57185 10 23 63

Total number of gains: 39; Total number of losses: 51; Total Number of normals: 398.  


 

Somatic mutations of NIPAL3:

 

Generating mutation plots.

 

Highly correlated genes for NIPAL3:

 

Showing top 20/671 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
NIPAL3TRIM80.825397404
NIPAL3ZNF6140.822953303
NIPAL3ARID1B0.817636303
NIPAL3KCTD150.814628303
NIPAL3ZNF5640.812466303
NIPAL3PCNT0.807676303
NIPAL3UROS0.791567303
NIPAL3MAN2B20.782668303
NIPAL3USP240.78108303
NIPAL3NUDCD30.7679303
NIPAL3FBXW80.766389303
NIPAL3SGMS20.76262303
NIPAL3ZNF7910.762246303
NIPAL3ATP6V1H0.750645404
NIPAL3DCAF160.747121303
NIPAL3KIAA20130.745597303
NIPAL3PEX30.745465303
NIPAL3TMEM126A0.744347303
NIPAL3CNOT6L0.743284404
NIPAL3SLC30A50.743098303

For details and further investigation, click here