| Full name: kelch repeat and BTB domain containing 6 | Alias Symbol: DKFZp547E1912 | ||
| Type: protein-coding gene | Cytoband: 13q14.11 | ||
| Entrez ID: 89890 | HGNC ID: HGNC:25340 | Ensembl Gene: ENSG00000165572 | OMIM ID: 617738 |
| Drug and gene relationship at DGIdb | |||
Expression of KBTBD6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KBTBD6 | 89890 | 226479_at | 1.4699 | 0.0240 | |
| GSE26886 | KBTBD6 | 89890 | 226479_at | -0.2546 | 0.5838 | |
| GSE45670 | KBTBD6 | 89890 | 226479_at | 0.6016 | 0.0164 | |
| GSE53622 | KBTBD6 | 89890 | 34630 | 0.1693 | 0.1845 | |
| GSE53624 | KBTBD6 | 89890 | 34630 | 0.6241 | 0.0000 | |
| GSE63941 | KBTBD6 | 89890 | 226479_at | -1.3955 | 0.0003 | |
| GSE77861 | KBTBD6 | 89890 | 226479_at | 0.6273 | 0.0906 | |
| GSE97050 | KBTBD6 | 89890 | A_33_P3268174 | -0.1795 | 0.3324 | |
| SRP007169 | KBTBD6 | 89890 | RNAseq | 0.6352 | 0.1718 | |
| SRP008496 | KBTBD6 | 89890 | RNAseq | 0.7764 | 0.0303 | |
| SRP064894 | KBTBD6 | 89890 | RNAseq | 0.7411 | 0.0000 | |
| SRP133303 | KBTBD6 | 89890 | RNAseq | 0.2936 | 0.0468 | |
| SRP159526 | KBTBD6 | 89890 | RNAseq | 0.4795 | 0.1004 | |
| SRP193095 | KBTBD6 | 89890 | RNAseq | 0.2691 | 0.0028 | |
| SRP219564 | KBTBD6 | 89890 | RNAseq | 0.7897 | 0.0009 | |
| TCGA | KBTBD6 | 89890 | RNAseq | 0.0954 | 0.1387 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by KBTBD6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KBTBD6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KBTBD6 | 89890 | 0 | 15 | 15 | |
| GSE20123 | KBTBD6 | 89890 | 0 | 14 | 16 | |
| GSE43470 | KBTBD6 | 89890 | 3 | 13 | 27 | |
| GSE46452 | KBTBD6 | 89890 | 0 | 33 | 26 | |
| GSE47630 | KBTBD6 | 89890 | 2 | 27 | 11 | |
| GSE54993 | KBTBD6 | 89890 | 12 | 2 | 56 | |
| GSE54994 | KBTBD6 | 89890 | 1 | 16 | 36 | |
| GSE60625 | KBTBD6 | 89890 | 0 | 3 | 8 | |
| GSE74703 | KBTBD6 | 89890 | 3 | 10 | 23 | |
| GSE74704 | KBTBD6 | 89890 | 0 | 11 | 9 | |
| TCGA | KBTBD6 | 89890 | 7 | 40 | 49 |
Total number of gains: 28; Total number of losses: 184; Total Number of normals: 276.
Somatic mutations of KBTBD6:
Generating mutation plots.
Highly correlated genes for KBTBD6:
Showing top 20/936 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KBTBD6 | LRRC58 | 0.825234 | 3 | 0 | 3 |
| KBTBD6 | UBQLN4 | 0.811698 | 3 | 0 | 3 |
| KBTBD6 | SNTB2 | 0.810978 | 3 | 0 | 3 |
| KBTBD6 | ZNF451 | 0.797438 | 3 | 0 | 3 |
| KBTBD6 | ANKRD10 | 0.792516 | 3 | 0 | 3 |
| KBTBD6 | SLC7A6OS | 0.790437 | 3 | 0 | 3 |
| KBTBD6 | DGKH | 0.789506 | 4 | 0 | 4 |
| KBTBD6 | GSK3B | 0.787529 | 3 | 0 | 3 |
| KBTBD6 | ELF4 | 0.785598 | 4 | 0 | 4 |
| KBTBD6 | SGTB | 0.770431 | 3 | 0 | 3 |
| KBTBD6 | ZMAT3 | 0.770144 | 3 | 0 | 3 |
| KBTBD6 | VAPB | 0.769604 | 3 | 0 | 3 |
| KBTBD6 | RAD21 | 0.76843 | 4 | 0 | 4 |
| KBTBD6 | CEP350 | 0.767813 | 3 | 0 | 3 |
| KBTBD6 | SEC16A | 0.76697 | 3 | 0 | 3 |
| KBTBD6 | FBN1 | 0.761364 | 3 | 0 | 3 |
| KBTBD6 | KBTBD7 | 0.761245 | 9 | 0 | 9 |
| KBTBD6 | CCDC91 | 0.758841 | 3 | 0 | 3 |
| KBTBD6 | RGL1 | 0.758579 | 3 | 0 | 3 |
| KBTBD6 | ERVW-1 | 0.757718 | 3 | 0 | 3 |
For details and further investigation, click here
