| Full name: transmembrane protein 129 | Alias Symbol: D4S2561E | ||
| Type: protein-coding gene | Cytoband: 4p16.3 | ||
| Entrez ID: 92305 | HGNC ID: HGNC:25137 | Ensembl Gene: ENSG00000168936 | OMIM ID: 615975 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of TMEM129:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM129 | 92305 | 225587_at | 0.0351 | 0.9009 | |
| GSE26886 | TMEM129 | 92305 | 225587_at | -0.0368 | 0.8556 | |
| GSE45670 | TMEM129 | 92305 | 225588_s_at | -0.3649 | 0.0213 | |
| GSE53622 | TMEM129 | 92305 | 27334 | -0.4692 | 0.0000 | |
| GSE53624 | TMEM129 | 92305 | 27334 | -0.3996 | 0.0000 | |
| GSE63941 | TMEM129 | 92305 | 225587_at | -1.1289 | 0.0000 | |
| GSE77861 | TMEM129 | 92305 | 225587_at | -0.2365 | 0.2210 | |
| GSE97050 | TMEM129 | 92305 | A_23_P354175 | -0.6653 | 0.0828 | |
| SRP007169 | TMEM129 | 92305 | RNAseq | -0.7037 | 0.0759 | |
| SRP008496 | TMEM129 | 92305 | RNAseq | -0.2385 | 0.5041 | |
| SRP064894 | TMEM129 | 92305 | RNAseq | -0.0229 | 0.9256 | |
| SRP133303 | TMEM129 | 92305 | RNAseq | -0.5211 | 0.0004 | |
| SRP159526 | TMEM129 | 92305 | RNAseq | -0.2636 | 0.1430 | |
| SRP193095 | TMEM129 | 92305 | RNAseq | -0.4980 | 0.0001 | |
| SRP219564 | TMEM129 | 92305 | RNAseq | -0.1235 | 0.8224 | |
| TCGA | TMEM129 | 92305 | RNAseq | -0.2927 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by TMEM129 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM129:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM129 | 92305 | 0 | 16 | 14 | |
| GSE20123 | TMEM129 | 92305 | 0 | 16 | 14 | |
| GSE43470 | TMEM129 | 92305 | 1 | 16 | 26 | |
| GSE46452 | TMEM129 | 92305 | 1 | 36 | 22 | |
| GSE47630 | TMEM129 | 92305 | 2 | 19 | 19 | |
| GSE54993 | TMEM129 | 92305 | 11 | 0 | 59 | |
| GSE54994 | TMEM129 | 92305 | 3 | 12 | 38 | |
| GSE60625 | TMEM129 | 92305 | 0 | 0 | 11 | |
| GSE74703 | TMEM129 | 92305 | 1 | 12 | 23 | |
| GSE74704 | TMEM129 | 92305 | 0 | 8 | 12 | |
| TCGA | TMEM129 | 92305 | 9 | 47 | 40 |
Total number of gains: 28; Total number of losses: 182; Total Number of normals: 278.
Somatic mutations of TMEM129:
Generating mutation plots.
Highly correlated genes for TMEM129:
Showing top 20/419 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM129 | STOML1 | 0.864449 | 3 | 0 | 3 |
| TMEM129 | SSNA1 | 0.830789 | 3 | 0 | 3 |
| TMEM129 | SLC24A1 | 0.801673 | 3 | 0 | 3 |
| TMEM129 | PSKH1 | 0.774973 | 3 | 0 | 3 |
| TMEM129 | AKT1S1 | 0.774427 | 3 | 0 | 3 |
| TMEM129 | RAB11FIP5 | 0.773337 | 3 | 0 | 3 |
| TMEM129 | CNP | 0.773104 | 3 | 0 | 3 |
| TMEM129 | EIF4G3 | 0.756481 | 3 | 0 | 3 |
| TMEM129 | PGLS | 0.756407 | 3 | 0 | 3 |
| TMEM129 | ARID1B | 0.74873 | 3 | 0 | 3 |
| TMEM129 | GALNT11 | 0.748571 | 3 | 0 | 3 |
| TMEM129 | EPM2AIP1 | 0.745495 | 3 | 0 | 3 |
| TMEM129 | ELF2 | 0.744829 | 3 | 0 | 3 |
| TMEM129 | LBX1 | 0.744708 | 3 | 0 | 3 |
| TMEM129 | KIAA1143 | 0.73909 | 3 | 0 | 3 |
| TMEM129 | MED25 | 0.738531 | 3 | 0 | 3 |
| TMEM129 | MAPK7 | 0.735213 | 3 | 0 | 3 |
| TMEM129 | CCDC97 | 0.732997 | 3 | 0 | 3 |
| TMEM129 | NDUFA3 | 0.726832 | 3 | 0 | 3 |
| TMEM129 | ARHGAP31 | 0.726206 | 3 | 0 | 3 |
For details and further investigation, click here
