| Full name: mannosidase alpha class 2B member 2 | Alias Symbol: KIAA0935 | ||
| Type: protein-coding gene | Cytoband: 4p16.1 | ||
| Entrez ID: 23324 | HGNC ID: HGNC:29623 | Ensembl Gene: ENSG00000013288 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of MAN2B2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MAN2B2 | 23324 | 214703_s_at | -0.0892 | 0.8836 | |
| GSE20347 | MAN2B2 | 23324 | 214703_s_at | -0.5496 | 0.0001 | |
| GSE23400 | MAN2B2 | 23324 | 214703_s_at | -0.1605 | 0.0023 | |
| GSE26886 | MAN2B2 | 23324 | 214703_s_at | 0.1156 | 0.7171 | |
| GSE29001 | MAN2B2 | 23324 | 214703_s_at | -0.1359 | 0.4469 | |
| GSE38129 | MAN2B2 | 23324 | 214703_s_at | -0.5443 | 0.0001 | |
| GSE45670 | MAN2B2 | 23324 | 214703_s_at | -0.4039 | 0.0147 | |
| GSE63941 | MAN2B2 | 23324 | 214703_s_at | -1.7142 | 0.0022 | |
| GSE77861 | MAN2B2 | 23324 | 214703_s_at | -0.3550 | 0.1241 | |
| GSE97050 | MAN2B2 | 23324 | A_23_P250380 | -0.0642 | 0.7863 | |
| SRP007169 | MAN2B2 | 23324 | RNAseq | 0.7865 | 0.1412 | |
| SRP008496 | MAN2B2 | 23324 | RNAseq | 0.9165 | 0.0161 | |
| SRP064894 | MAN2B2 | 23324 | RNAseq | 0.4039 | 0.0148 | |
| SRP133303 | MAN2B2 | 23324 | RNAseq | -0.0818 | 0.6351 | |
| SRP159526 | MAN2B2 | 23324 | RNAseq | -0.1642 | 0.3542 | |
| SRP193095 | MAN2B2 | 23324 | RNAseq | -0.1006 | 0.4903 | |
| SRP219564 | MAN2B2 | 23324 | RNAseq | 0.3721 | 0.1995 | |
| TCGA | MAN2B2 | 23324 | RNAseq | -0.2549 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by MAN2B2 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of MAN2B2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MAN2B2 | 23324 | 0 | 18 | 12 | |
| GSE20123 | MAN2B2 | 23324 | 0 | 18 | 12 | |
| GSE43470 | MAN2B2 | 23324 | 0 | 17 | 26 | |
| GSE46452 | MAN2B2 | 23324 | 1 | 36 | 22 | |
| GSE47630 | MAN2B2 | 23324 | 1 | 19 | 20 | |
| GSE54993 | MAN2B2 | 23324 | 10 | 0 | 60 | |
| GSE54994 | MAN2B2 | 23324 | 3 | 12 | 38 | |
| GSE60625 | MAN2B2 | 23324 | 0 | 0 | 11 | |
| GSE74703 | MAN2B2 | 23324 | 0 | 13 | 23 | |
| GSE74704 | MAN2B2 | 23324 | 0 | 10 | 10 | |
| TCGA | MAN2B2 | 23324 | 7 | 48 | 41 |
Total number of gains: 22; Total number of losses: 191; Total Number of normals: 275.
Somatic mutations of MAN2B2:
Generating mutation plots.
Highly correlated genes for MAN2B2:
Showing top 20/700 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MAN2B2 | SHISA5 | 0.840298 | 3 | 0 | 3 |
| MAN2B2 | UFM1 | 0.811166 | 3 | 0 | 3 |
| MAN2B2 | ARID1B | 0.793922 | 3 | 0 | 3 |
| MAN2B2 | NIPAL3 | 0.782668 | 3 | 0 | 3 |
| MAN2B2 | POMP | 0.766996 | 3 | 0 | 3 |
| MAN2B2 | DNALI1 | 0.759192 | 3 | 0 | 3 |
| MAN2B2 | METTL14 | 0.756188 | 3 | 0 | 3 |
| MAN2B2 | ZBED6 | 0.75404 | 3 | 0 | 3 |
| MAN2B2 | PFDN1 | 0.752111 | 3 | 0 | 3 |
| MAN2B2 | TRIP12 | 0.745364 | 3 | 0 | 3 |
| MAN2B2 | TBC1D20 | 0.743324 | 3 | 0 | 3 |
| MAN2B2 | ANXA6 | 0.741345 | 3 | 0 | 3 |
| MAN2B2 | PBRM1 | 0.738485 | 4 | 0 | 4 |
| MAN2B2 | RHBDF1 | 0.736993 | 4 | 0 | 4 |
| MAN2B2 | FBLN5 | 0.736408 | 4 | 0 | 4 |
| MAN2B2 | LRRN4CL | 0.732447 | 3 | 0 | 3 |
| MAN2B2 | CNOT2 | 0.729003 | 3 | 0 | 3 |
| MAN2B2 | ZNF529 | 0.72427 | 3 | 0 | 3 |
| MAN2B2 | NSG1 | 0.722495 | 3 | 0 | 3 |
| MAN2B2 | CHID1 | 0.722371 | 3 | 0 | 3 |
For details and further investigation, click here
