| Full name: ankyrin repeat and SOCS box containing 6 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 9q34.11 | ||
| Entrez ID: 140459 | HGNC ID: HGNC:17181 | Ensembl Gene: ENSG00000148331 | OMIM ID: 615051 |
| Drug and gene relationship at DGIdb | |||
Expression of ASB6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ASB6 | 140459 | 221657_s_at | 0.4874 | 0.1478 | |
| GSE20347 | ASB6 | 140459 | 221657_s_at | 0.0270 | 0.8095 | |
| GSE23400 | ASB6 | 140459 | 221657_s_at | 0.2502 | 0.0000 | |
| GSE26886 | ASB6 | 140459 | 221657_s_at | 0.4000 | 0.0125 | |
| GSE29001 | ASB6 | 140459 | 221657_s_at | 0.0775 | 0.6367 | |
| GSE38129 | ASB6 | 140459 | 221657_s_at | 0.0734 | 0.4881 | |
| GSE45670 | ASB6 | 140459 | 221657_s_at | 0.2947 | 0.0034 | |
| GSE63941 | ASB6 | 140459 | 221657_s_at | -0.0918 | 0.7833 | |
| GSE77861 | ASB6 | 140459 | 221657_s_at | 0.0037 | 0.9812 | |
| GSE97050 | ASB6 | 140459 | A_32_P412313 | 0.0676 | 0.7591 | |
| SRP007169 | ASB6 | 140459 | RNAseq | 0.2059 | 0.6149 | |
| SRP008496 | ASB6 | 140459 | RNAseq | 0.4224 | 0.2456 | |
| SRP064894 | ASB6 | 140459 | RNAseq | 0.2411 | 0.1939 | |
| SRP133303 | ASB6 | 140459 | RNAseq | 0.1136 | 0.4215 | |
| SRP159526 | ASB6 | 140459 | RNAseq | 0.2323 | 0.4932 | |
| SRP193095 | ASB6 | 140459 | RNAseq | 0.2366 | 0.0010 | |
| SRP219564 | ASB6 | 140459 | RNAseq | -0.1299 | 0.5981 | |
| TCGA | ASB6 | 140459 | RNAseq | 0.0280 | 0.5827 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ASB6 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of ASB6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ASB6 | 140459 | 6 | 9 | 15 | |
| GSE20123 | ASB6 | 140459 | 6 | 9 | 15 | |
| GSE43470 | ASB6 | 140459 | 5 | 8 | 30 | |
| GSE46452 | ASB6 | 140459 | 6 | 13 | 40 | |
| GSE47630 | ASB6 | 140459 | 3 | 16 | 21 | |
| GSE54993 | ASB6 | 140459 | 3 | 3 | 64 | |
| GSE54994 | ASB6 | 140459 | 12 | 9 | 32 | |
| GSE60625 | ASB6 | 140459 | 0 | 0 | 11 | |
| GSE74703 | ASB6 | 140459 | 5 | 6 | 25 | |
| GSE74704 | ASB6 | 140459 | 3 | 7 | 10 | |
| TCGA | ASB6 | 140459 | 27 | 26 | 43 |
Total number of gains: 76; Total number of losses: 106; Total Number of normals: 306.
Somatic mutations of ASB6:
Generating mutation plots.
Highly correlated genes for ASB6:
Showing top 20/362 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ASB6 | SLC34A1 | 0.777683 | 3 | 0 | 3 |
| ASB6 | ALDH16A1 | 0.745648 | 3 | 0 | 3 |
| ASB6 | GAS6-AS1 | 0.725393 | 3 | 0 | 3 |
| ASB6 | GPN2 | 0.722896 | 3 | 0 | 3 |
| ASB6 | LRSAM1 | 0.720106 | 3 | 0 | 3 |
| ASB6 | SCN2B | 0.708015 | 3 | 0 | 3 |
| ASB6 | CC2D1B | 0.702556 | 4 | 0 | 3 |
| ASB6 | JSRP1 | 0.701954 | 3 | 0 | 3 |
| ASB6 | CDK16 | 0.701563 | 4 | 0 | 4 |
| ASB6 | GLDC | 0.695712 | 3 | 0 | 3 |
| ASB6 | WNT9A | 0.694772 | 3 | 0 | 3 |
| ASB6 | FBXL8 | 0.69224 | 4 | 0 | 3 |
| ASB6 | CBS | 0.691568 | 4 | 0 | 4 |
| ASB6 | ELAVL3 | 0.6898 | 3 | 0 | 3 |
| ASB6 | STK32C | 0.68853 | 4 | 0 | 4 |
| ASB6 | HDAC7 | 0.687405 | 3 | 0 | 3 |
| ASB6 | TMEM102 | 0.686165 | 4 | 0 | 4 |
| ASB6 | LRFN1 | 0.684189 | 3 | 0 | 3 |
| ASB6 | HAPLN3 | 0.683141 | 3 | 0 | 3 |
| ASB6 | ING5 | 0.682343 | 3 | 0 | 3 |
For details and further investigation, click here
