| Full name: leucine rich repeat and sterile alpha motif containing 1 | Alias Symbol: FLJ31641|CMT2P | ||
| Type: protein-coding gene | Cytoband: 9q33.3-q34.11 | ||
| Entrez ID: 90678 | HGNC ID: HGNC:25135 | Ensembl Gene: ENSG00000148356 | OMIM ID: 610933 |
| Drug and gene relationship at DGIdb | |||
Expression of LRSAM1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LRSAM1 | 90678 | 227675_at | -0.0401 | 0.8982 | |
| GSE26886 | LRSAM1 | 90678 | 227675_at | 0.1810 | 0.1795 | |
| GSE45670 | LRSAM1 | 90678 | 227675_at | 0.0580 | 0.5098 | |
| GSE53622 | LRSAM1 | 90678 | 41739 | -0.1021 | 0.1094 | |
| GSE53624 | LRSAM1 | 90678 | 41739 | -0.0887 | 0.2959 | |
| GSE63941 | LRSAM1 | 90678 | 227675_at | 0.7819 | 0.0321 | |
| GSE77861 | LRSAM1 | 90678 | 227675_at | 0.0492 | 0.8028 | |
| GSE97050 | LRSAM1 | 90678 | A_23_P123916 | -0.0353 | 0.8864 | |
| SRP007169 | LRSAM1 | 90678 | RNAseq | -0.1363 | 0.7699 | |
| SRP008496 | LRSAM1 | 90678 | RNAseq | -0.3554 | 0.3417 | |
| SRP064894 | LRSAM1 | 90678 | RNAseq | 0.3718 | 0.0904 | |
| SRP133303 | LRSAM1 | 90678 | RNAseq | -0.5218 | 0.0016 | |
| SRP159526 | LRSAM1 | 90678 | RNAseq | -0.2841 | 0.2157 | |
| SRP193095 | LRSAM1 | 90678 | RNAseq | -0.2541 | 0.0893 | |
| SRP219564 | LRSAM1 | 90678 | RNAseq | -0.0892 | 0.7320 | |
| TCGA | LRSAM1 | 90678 | RNAseq | -0.0863 | 0.1274 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LRSAM1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LRSAM1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LRSAM1 | 90678 | 6 | 9 | 15 | |
| GSE20123 | LRSAM1 | 90678 | 6 | 9 | 15 | |
| GSE43470 | LRSAM1 | 90678 | 5 | 6 | 32 | |
| GSE46452 | LRSAM1 | 90678 | 6 | 13 | 40 | |
| GSE47630 | LRSAM1 | 90678 | 3 | 16 | 21 | |
| GSE54993 | LRSAM1 | 90678 | 3 | 3 | 64 | |
| GSE54994 | LRSAM1 | 90678 | 11 | 8 | 34 | |
| GSE60625 | LRSAM1 | 90678 | 0 | 0 | 11 | |
| GSE74703 | LRSAM1 | 90678 | 5 | 4 | 27 | |
| GSE74704 | LRSAM1 | 90678 | 3 | 7 | 10 | |
| TCGA | LRSAM1 | 90678 | 27 | 25 | 44 |
Total number of gains: 75; Total number of losses: 100; Total Number of normals: 313.
Somatic mutations of LRSAM1:
Generating mutation plots.
Highly correlated genes for LRSAM1:
Showing top 20/331 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LRSAM1 | YY2 | 0.838746 | 3 | 0 | 3 |
| LRSAM1 | OR10AD1 | 0.815202 | 3 | 0 | 3 |
| LRSAM1 | PRSS38 | 0.79946 | 3 | 0 | 3 |
| LRSAM1 | OTOG | 0.79405 | 3 | 0 | 3 |
| LRSAM1 | PAX2 | 0.786675 | 3 | 0 | 3 |
| LRSAM1 | INSC | 0.783938 | 3 | 0 | 3 |
| LRSAM1 | AGPAT2 | 0.783219 | 3 | 0 | 3 |
| LRSAM1 | LBX2 | 0.780905 | 3 | 0 | 3 |
| LRSAM1 | TNFAIP8L1 | 0.779635 | 3 | 0 | 3 |
| LRSAM1 | PLA2G2C | 0.767027 | 3 | 0 | 3 |
| LRSAM1 | OR2T27 | 0.765623 | 3 | 0 | 3 |
| LRSAM1 | GDF7 | 0.763023 | 3 | 0 | 3 |
| LRSAM1 | KRTAP10-12 | 0.762599 | 3 | 0 | 3 |
| LRSAM1 | LINC00894 | 0.760553 | 3 | 0 | 3 |
| LRSAM1 | FOXA3 | 0.758825 | 4 | 0 | 4 |
| LRSAM1 | STRC | 0.758059 | 3 | 0 | 3 |
| LRSAM1 | ZNF236 | 0.754061 | 3 | 0 | 3 |
| LRSAM1 | SAMD4A | 0.752271 | 3 | 0 | 3 |
| LRSAM1 | MYOD1 | 0.750657 | 4 | 0 | 4 |
| LRSAM1 | MYBPH | 0.747699 | 3 | 0 | 3 |
For details and further investigation, click here
