| Full name: hyaluronan and proteoglycan link protein 3 | Alias Symbol: HsT19883 | ||
| Type: protein-coding gene | Cytoband: 15q26.1 | ||
| Entrez ID: 145864 | HGNC ID: HGNC:21446 | Ensembl Gene: ENSG00000140511 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of HAPLN3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HAPLN3 | 145864 | 227262_at | 0.4734 | 0.2618 | |
| GSE26886 | HAPLN3 | 145864 | 227262_at | 0.0277 | 0.9267 | |
| GSE45670 | HAPLN3 | 145864 | 227262_at | 0.3082 | 0.0049 | |
| GSE53622 | HAPLN3 | 145864 | 69019 | 1.2091 | 0.0000 | |
| GSE53624 | HAPLN3 | 145864 | 69019 | 1.3620 | 0.0000 | |
| GSE63941 | HAPLN3 | 145864 | 227262_at | 0.1444 | 0.6706 | |
| GSE77861 | HAPLN3 | 145864 | 227262_at | 0.1672 | 0.3816 | |
| GSE97050 | HAPLN3 | 145864 | A_33_P3259393 | 0.8177 | 0.2027 | |
| SRP007169 | HAPLN3 | 145864 | RNAseq | 1.9383 | 0.0002 | |
| SRP008496 | HAPLN3 | 145864 | RNAseq | 1.7232 | 0.0000 | |
| SRP064894 | HAPLN3 | 145864 | RNAseq | 1.2085 | 0.0002 | |
| SRP133303 | HAPLN3 | 145864 | RNAseq | 1.3409 | 0.0000 | |
| SRP159526 | HAPLN3 | 145864 | RNAseq | 0.5921 | 0.0505 | |
| SRP193095 | HAPLN3 | 145864 | RNAseq | 1.6985 | 0.0000 | |
| SRP219564 | HAPLN3 | 145864 | RNAseq | 1.0209 | 0.0113 | |
| TCGA | HAPLN3 | 145864 | RNAseq | 0.6938 | 0.0000 |
Upregulated datasets: 8; Downregulated datasets: 0.
Survival by HAPLN3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HAPLN3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HAPLN3 | 145864 | 7 | 3 | 20 | |
| GSE20123 | HAPLN3 | 145864 | 7 | 3 | 20 | |
| GSE43470 | HAPLN3 | 145864 | 5 | 4 | 34 | |
| GSE46452 | HAPLN3 | 145864 | 3 | 7 | 49 | |
| GSE47630 | HAPLN3 | 145864 | 8 | 11 | 21 | |
| GSE54993 | HAPLN3 | 145864 | 4 | 6 | 60 | |
| GSE54994 | HAPLN3 | 145864 | 7 | 6 | 40 | |
| GSE60625 | HAPLN3 | 145864 | 4 | 0 | 7 | |
| GSE74703 | HAPLN3 | 145864 | 4 | 3 | 29 | |
| GSE74704 | HAPLN3 | 145864 | 4 | 2 | 14 | |
| TCGA | HAPLN3 | 145864 | 17 | 11 | 68 |
Total number of gains: 70; Total number of losses: 56; Total Number of normals: 362.
Somatic mutations of HAPLN3:
Generating mutation plots.
Highly correlated genes for HAPLN3:
Showing top 20/353 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HAPLN3 | RENBP | 0.733992 | 4 | 0 | 3 |
| HAPLN3 | SALL3 | 0.721324 | 3 | 0 | 3 |
| HAPLN3 | FCGR1B | 0.719555 | 4 | 0 | 4 |
| HAPLN3 | UBE2S | 0.714204 | 3 | 0 | 3 |
| HAPLN3 | CST1 | 0.707352 | 3 | 0 | 3 |
| HAPLN3 | CSMD2 | 0.705818 | 3 | 0 | 3 |
| HAPLN3 | PLA2G2D | 0.704796 | 3 | 0 | 3 |
| HAPLN3 | CD300LF | 0.691075 | 6 | 0 | 6 |
| HAPLN3 | DPM3 | 0.688947 | 3 | 0 | 3 |
| HAPLN3 | GNLY | 0.688398 | 5 | 0 | 5 |
| HAPLN3 | ACP5 | 0.688165 | 3 | 0 | 3 |
| HAPLN3 | ASB6 | 0.683141 | 3 | 0 | 3 |
| HAPLN3 | MYO10 | 0.682027 | 3 | 0 | 3 |
| HAPLN3 | CD3G | 0.681222 | 3 | 0 | 3 |
| HAPLN3 | CALR | 0.678938 | 3 | 0 | 3 |
| HAPLN3 | MMP11 | 0.678143 | 4 | 0 | 4 |
| HAPLN3 | GZMB | 0.675439 | 5 | 0 | 5 |
| HAPLN3 | CD8B | 0.669135 | 4 | 0 | 3 |
| HAPLN3 | DCPS | 0.6682 | 3 | 0 | 3 |
| HAPLN3 | ZFAT | 0.666179 | 3 | 0 | 3 |
For details and further investigation, click here
