| Full name: histone deacetylase 7 | Alias Symbol: DKFZP586J0917 | ||
| Type: protein-coding gene | Cytoband: 12q13.11 | ||
| Entrez ID: 51564 | HGNC ID: HGNC:14067 | Ensembl Gene: ENSG00000061273 | OMIM ID: 606542 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of HDAC7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HDAC7 | 51564 | 217937_s_at | 0.3221 | 0.3079 | |
| GSE20347 | HDAC7 | 51564 | 217937_s_at | 0.1867 | 0.0564 | |
| GSE23400 | HDAC7 | 51564 | 217937_s_at | -0.0119 | 0.7878 | |
| GSE26886 | HDAC7 | 51564 | 217937_s_at | 0.4972 | 0.0009 | |
| GSE29001 | HDAC7 | 51564 | 217937_s_at | -0.1193 | 0.5737 | |
| GSE38129 | HDAC7 | 51564 | 217937_s_at | 0.0328 | 0.7705 | |
| GSE45670 | HDAC7 | 51564 | 217937_s_at | -0.0772 | 0.4107 | |
| GSE63941 | HDAC7 | 51564 | 217937_s_at | -0.4072 | 0.1083 | |
| GSE77861 | HDAC7 | 51564 | 217937_s_at | 0.0132 | 0.9450 | |
| GSE97050 | HDAC7 | 51564 | A_23_P2582 | -0.0003 | 0.9986 | |
| SRP007169 | HDAC7 | 51564 | RNAseq | 0.2617 | 0.5426 | |
| SRP008496 | HDAC7 | 51564 | RNAseq | -0.1059 | 0.7177 | |
| SRP064894 | HDAC7 | 51564 | RNAseq | 0.4112 | 0.0248 | |
| SRP133303 | HDAC7 | 51564 | RNAseq | -0.1027 | 0.4260 | |
| SRP159526 | HDAC7 | 51564 | RNAseq | -0.1007 | 0.5500 | |
| SRP193095 | HDAC7 | 51564 | RNAseq | 0.6112 | 0.0001 | |
| SRP219564 | HDAC7 | 51564 | RNAseq | 0.1384 | 0.6575 | |
| TCGA | HDAC7 | 51564 | RNAseq | -0.0263 | 0.5666 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by HDAC7 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of HDAC7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HDAC7 | 51564 | 6 | 1 | 23 | |
| GSE20123 | HDAC7 | 51564 | 6 | 1 | 23 | |
| GSE43470 | HDAC7 | 51564 | 3 | 1 | 39 | |
| GSE46452 | HDAC7 | 51564 | 8 | 1 | 50 | |
| GSE47630 | HDAC7 | 51564 | 11 | 2 | 27 | |
| GSE54993 | HDAC7 | 51564 | 0 | 5 | 65 | |
| GSE54994 | HDAC7 | 51564 | 6 | 1 | 46 | |
| GSE60625 | HDAC7 | 51564 | 0 | 0 | 11 | |
| GSE74703 | HDAC7 | 51564 | 3 | 1 | 32 | |
| GSE74704 | HDAC7 | 51564 | 4 | 1 | 15 | |
| TCGA | HDAC7 | 51564 | 16 | 12 | 68 |
Total number of gains: 63; Total number of losses: 26; Total Number of normals: 399.
Somatic mutations of HDAC7:
Generating mutation plots.
Highly correlated genes for HDAC7:
Showing top 20/436 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HDAC7 | ZNF628 | 0.776555 | 3 | 0 | 3 |
| HDAC7 | SPSB1 | 0.770473 | 3 | 0 | 3 |
| HDAC7 | GAS6-AS1 | 0.755443 | 3 | 0 | 3 |
| HDAC7 | ZNF316 | 0.72976 | 4 | 0 | 4 |
| HDAC7 | GPR162 | 0.717984 | 3 | 0 | 3 |
| HDAC7 | CBS | 0.716899 | 3 | 0 | 3 |
| HDAC7 | ADARB1 | 0.701889 | 3 | 0 | 3 |
| HDAC7 | FAM53A | 0.701828 | 3 | 0 | 3 |
| HDAC7 | ATAD3A | 0.700052 | 3 | 0 | 3 |
| HDAC7 | YDJC | 0.699671 | 3 | 0 | 3 |
| HDAC7 | MRPL55 | 0.697897 | 4 | 0 | 4 |
| HDAC7 | EXTL1 | 0.696856 | 4 | 0 | 3 |
| HDAC7 | SYNPO | 0.696797 | 3 | 0 | 3 |
| HDAC7 | FOXP4 | 0.696708 | 3 | 0 | 3 |
| HDAC7 | METTL1 | 0.692885 | 3 | 0 | 3 |
| HDAC7 | FXR2 | 0.691473 | 5 | 0 | 5 |
| HDAC7 | ZNF683 | 0.6913 | 4 | 0 | 4 |
| HDAC7 | ASB6 | 0.687405 | 3 | 0 | 3 |
| HDAC7 | ELFN1 | 0.686616 | 3 | 0 | 3 |
| HDAC7 | SURF6 | 0.684985 | 3 | 0 | 3 |
For details and further investigation, click here
