| Full name: GPN-loop GTPase 2 | Alias Symbol: FLJ10349 | ||
| Type: protein-coding gene | Cytoband: 1p36.11 | ||
| Entrez ID: 54707 | HGNC ID: HGNC:25513 | Ensembl Gene: ENSG00000142751 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of GPN2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GPN2 | 54707 | 218799_at | 0.1522 | 0.6400 | |
| GSE20347 | GPN2 | 54707 | 218799_at | 0.0936 | 0.5213 | |
| GSE23400 | GPN2 | 54707 | 218799_at | 0.1001 | 0.0215 | |
| GSE26886 | GPN2 | 54707 | 218799_at | 0.3710 | 0.0495 | |
| GSE29001 | GPN2 | 54707 | 218799_at | 0.1231 | 0.7539 | |
| GSE38129 | GPN2 | 54707 | 218799_at | 0.2686 | 0.0232 | |
| GSE45670 | GPN2 | 54707 | 235058_at | -0.0641 | 0.6785 | |
| GSE53622 | GPN2 | 54707 | 16668 | 0.1614 | 0.0029 | |
| GSE53624 | GPN2 | 54707 | 16668 | 0.3653 | 0.0000 | |
| GSE63941 | GPN2 | 54707 | 218799_at | 0.5204 | 0.1115 | |
| GSE77861 | GPN2 | 54707 | 218799_at | -0.0386 | 0.8565 | |
| GSE97050 | GPN2 | 54707 | A_23_P138025 | 0.3135 | 0.2494 | |
| SRP007169 | GPN2 | 54707 | RNAseq | -0.0566 | 0.8757 | |
| SRP008496 | GPN2 | 54707 | RNAseq | 0.0368 | 0.8644 | |
| SRP064894 | GPN2 | 54707 | RNAseq | 0.3866 | 0.0078 | |
| SRP133303 | GPN2 | 54707 | RNAseq | 0.0626 | 0.5507 | |
| SRP159526 | GPN2 | 54707 | RNAseq | -0.0680 | 0.8031 | |
| SRP193095 | GPN2 | 54707 | RNAseq | -0.0147 | 0.8256 | |
| SRP219564 | GPN2 | 54707 | RNAseq | -0.1851 | 0.4371 | |
| TCGA | GPN2 | 54707 | RNAseq | -0.0214 | 0.7065 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GPN2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GPN2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GPN2 | 54707 | 0 | 6 | 24 | |
| GSE20123 | GPN2 | 54707 | 0 | 5 | 25 | |
| GSE43470 | GPN2 | 54707 | 2 | 6 | 35 | |
| GSE46452 | GPN2 | 54707 | 5 | 1 | 53 | |
| GSE47630 | GPN2 | 54707 | 8 | 3 | 29 | |
| GSE54993 | GPN2 | 54707 | 2 | 1 | 67 | |
| GSE54994 | GPN2 | 54707 | 10 | 4 | 39 | |
| GSE60625 | GPN2 | 54707 | 0 | 0 | 11 | |
| GSE74703 | GPN2 | 54707 | 1 | 4 | 31 | |
| GSE74704 | GPN2 | 54707 | 0 | 0 | 20 | |
| TCGA | GPN2 | 54707 | 10 | 24 | 62 |
Total number of gains: 38; Total number of losses: 54; Total Number of normals: 396.
Somatic mutations of GPN2:
Generating mutation plots.
Highly correlated genes for GPN2:
Showing top 20/159 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GPN2 | COG4 | 0.73298 | 3 | 0 | 3 |
| GPN2 | PPA2 | 0.730169 | 3 | 0 | 3 |
| GPN2 | TKTL1 | 0.729867 | 3 | 0 | 3 |
| GPN2 | ASB6 | 0.722896 | 3 | 0 | 3 |
| GPN2 | CACNA1A | 0.719268 | 3 | 0 | 3 |
| GPN2 | FUT10 | 0.716085 | 3 | 0 | 3 |
| GPN2 | RTN4RL1 | 0.707346 | 3 | 0 | 3 |
| GPN2 | REM2 | 0.698801 | 3 | 0 | 3 |
| GPN2 | MSR1 | 0.67804 | 3 | 0 | 3 |
| GPN2 | MARCO | 0.676891 | 3 | 0 | 3 |
| GPN2 | FAM151A | 0.673654 | 3 | 0 | 3 |
| GPN2 | SWI5 | 0.673249 | 4 | 0 | 4 |
| GPN2 | JSRP1 | 0.660265 | 3 | 0 | 3 |
| GPN2 | HS2ST1 | 0.651207 | 5 | 0 | 4 |
| GPN2 | ALDH16A1 | 0.646347 | 4 | 0 | 3 |
| GPN2 | PLA2G2F | 0.645807 | 4 | 0 | 3 |
| GPN2 | BAX | 0.643524 | 4 | 0 | 3 |
| GPN2 | STK32C | 0.64104 | 4 | 0 | 3 |
| GPN2 | RFT1 | 0.628519 | 5 | 0 | 4 |
| GPN2 | PAFAH2 | 0.628046 | 4 | 0 | 4 |
For details and further investigation, click here
