| Full name: aldehyde dehydrogenase 16 family member A1 | Alias Symbol: MGC10204 | ||
| Type: protein-coding gene | Cytoband: 19q13.33 | ||
| Entrez ID: 126133 | HGNC ID: HGNC:28114 | Ensembl Gene: ENSG00000161618 | OMIM ID: 613358 |
| Drug and gene relationship at DGIdb | |||
Expression of ALDH16A1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ALDH16A1 | 126133 | 227592_at | 0.6529 | 0.2233 | |
| GSE26886 | ALDH16A1 | 126133 | 227592_at | 0.4524 | 0.0199 | |
| GSE45670 | ALDH16A1 | 126133 | 227592_at | 0.3537 | 0.0034 | |
| GSE53622 | ALDH16A1 | 126133 | 52156 | 0.2161 | 0.0195 | |
| GSE53624 | ALDH16A1 | 126133 | 52156 | 0.4764 | 0.0000 | |
| GSE63941 | ALDH16A1 | 126133 | 227592_at | 0.5461 | 0.3064 | |
| GSE77861 | ALDH16A1 | 126133 | 227592_at | 0.1449 | 0.5812 | |
| GSE97050 | ALDH16A1 | 126133 | A_24_P5743 | 0.4188 | 0.1974 | |
| SRP007169 | ALDH16A1 | 126133 | RNAseq | -0.4301 | 0.3434 | |
| SRP008496 | ALDH16A1 | 126133 | RNAseq | -0.1469 | 0.6427 | |
| SRP064894 | ALDH16A1 | 126133 | RNAseq | 1.0124 | 0.0001 | |
| SRP133303 | ALDH16A1 | 126133 | RNAseq | 0.1333 | 0.5837 | |
| SRP159526 | ALDH16A1 | 126133 | RNAseq | 0.3587 | 0.0686 | |
| SRP193095 | ALDH16A1 | 126133 | RNAseq | 0.2164 | 0.0900 | |
| SRP219564 | ALDH16A1 | 126133 | RNAseq | 0.7225 | 0.0058 | |
| TCGA | ALDH16A1 | 126133 | RNAseq | 0.1102 | 0.0408 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ALDH16A1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ALDH16A1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ALDH16A1 | 126133 | 4 | 4 | 22 | |
| GSE20123 | ALDH16A1 | 126133 | 4 | 3 | 23 | |
| GSE43470 | ALDH16A1 | 126133 | 4 | 11 | 28 | |
| GSE46452 | ALDH16A1 | 126133 | 45 | 1 | 13 | |
| GSE47630 | ALDH16A1 | 126133 | 10 | 6 | 24 | |
| GSE54993 | ALDH16A1 | 126133 | 17 | 4 | 49 | |
| GSE54994 | ALDH16A1 | 126133 | 4 | 14 | 35 | |
| GSE60625 | ALDH16A1 | 126133 | 9 | 0 | 2 | |
| GSE74703 | ALDH16A1 | 126133 | 4 | 7 | 25 | |
| GSE74704 | ALDH16A1 | 126133 | 4 | 1 | 15 | |
| TCGA | ALDH16A1 | 126133 | 14 | 19 | 63 |
Total number of gains: 119; Total number of losses: 70; Total Number of normals: 299.
Somatic mutations of ALDH16A1:
Generating mutation plots.
Highly correlated genes for ALDH16A1:
Showing top 20/328 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ALDH16A1 | ASB6 | 0.745648 | 3 | 0 | 3 |
| ALDH16A1 | TMEM102 | 0.741315 | 4 | 0 | 4 |
| ALDH16A1 | BUB1B | 0.731986 | 3 | 0 | 3 |
| ALDH16A1 | HNRNPK | 0.728297 | 3 | 0 | 3 |
| ALDH16A1 | DPF1 | 0.727277 | 3 | 0 | 3 |
| ALDH16A1 | SLC34A1 | 0.703601 | 3 | 0 | 3 |
| ALDH16A1 | FAM24B | 0.701493 | 3 | 0 | 3 |
| ALDH16A1 | PSTPIP1 | 0.694804 | 3 | 0 | 3 |
| ALDH16A1 | CXorf56 | 0.690988 | 3 | 0 | 3 |
| ALDH16A1 | PAFAH1B3 | 0.688274 | 8 | 0 | 7 |
| ALDH16A1 | KRT9 | 0.688212 | 3 | 0 | 3 |
| ALDH16A1 | TEX13A | 0.686659 | 3 | 0 | 3 |
| ALDH16A1 | AKNA | 0.686474 | 4 | 0 | 4 |
| ALDH16A1 | NRF1 | 0.686314 | 4 | 0 | 3 |
| ALDH16A1 | PRR18 | 0.685147 | 3 | 0 | 3 |
| ALDH16A1 | EMC10 | 0.683986 | 5 | 0 | 5 |
| ALDH16A1 | DNAL4 | 0.683138 | 4 | 0 | 4 |
| ALDH16A1 | MANBA | 0.677123 | 3 | 0 | 3 |
| ALDH16A1 | MAT1A | 0.677115 | 3 | 0 | 3 |
| ALDH16A1 | RHBDD3 | 0.674411 | 4 | 0 | 3 |
For details and further investigation, click here
