| Full name: leucine rich repeat and fibronectin type III domain containing 1 | Alias Symbol: KIAA1484|SALM2 | ||
| Type: protein-coding gene | Cytoband: 19q13.2 | ||
| Entrez ID: 57622 | HGNC ID: HGNC:29290 | Ensembl Gene: ENSG00000128011 | OMIM ID: 612807 |
| Drug and gene relationship at DGIdb | |||
Expression of LRFN1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LRFN1 | 57622 | 232486_at | 0.7110 | 0.1492 | |
| GSE26886 | LRFN1 | 57622 | 232486_at | 0.4034 | 0.0138 | |
| GSE45670 | LRFN1 | 57622 | 232486_at | 0.1399 | 0.1902 | |
| GSE53622 | LRFN1 | 57622 | 111363 | 0.2106 | 0.0004 | |
| GSE53624 | LRFN1 | 57622 | 111363 | 0.2971 | 0.0000 | |
| GSE63941 | LRFN1 | 57622 | 232486_at | 0.6029 | 0.0556 | |
| GSE77861 | LRFN1 | 57622 | 232486_at | 0.0337 | 0.8396 | |
| GSE97050 | LRFN1 | 57622 | A_33_P3229552 | 0.2125 | 0.3451 | |
| SRP133303 | LRFN1 | 57622 | RNAseq | 1.2616 | 0.0003 | |
| SRP159526 | LRFN1 | 57622 | RNAseq | 2.5036 | 0.0001 | |
| SRP219564 | LRFN1 | 57622 | RNAseq | 2.1541 | 0.0024 | |
| TCGA | LRFN1 | 57622 | RNAseq | 0.5616 | 0.0005 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by LRFN1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LRFN1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LRFN1 | 57622 | 7 | 4 | 19 | |
| GSE20123 | LRFN1 | 57622 | 7 | 3 | 20 | |
| GSE43470 | LRFN1 | 57622 | 4 | 11 | 28 | |
| GSE46452 | LRFN1 | 57622 | 47 | 2 | 10 | |
| GSE47630 | LRFN1 | 57622 | 9 | 5 | 26 | |
| GSE54993 | LRFN1 | 57622 | 17 | 3 | 50 | |
| GSE54994 | LRFN1 | 57622 | 7 | 9 | 37 | |
| GSE60625 | LRFN1 | 57622 | 9 | 0 | 2 | |
| GSE74703 | LRFN1 | 57622 | 4 | 7 | 25 | |
| GSE74704 | LRFN1 | 57622 | 7 | 1 | 12 | |
| TCGA | LRFN1 | 57622 | 14 | 16 | 66 |
Total number of gains: 132; Total number of losses: 61; Total Number of normals: 295.
Somatic mutations of LRFN1:
Generating mutation plots.
Highly correlated genes for LRFN1:
Showing top 20/172 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LRFN1 | C16orf95 | 0.787911 | 3 | 0 | 3 |
| LRFN1 | EMID1 | 0.775067 | 3 | 0 | 3 |
| LRFN1 | RHBDL1 | 0.770466 | 3 | 0 | 3 |
| LRFN1 | APBA2 | 0.75765 | 3 | 0 | 3 |
| LRFN1 | RNF44 | 0.743427 | 3 | 0 | 3 |
| LRFN1 | CDH4 | 0.740507 | 3 | 0 | 3 |
| LRFN1 | HGD | 0.739347 | 3 | 0 | 3 |
| LRFN1 | HAUS5 | 0.739268 | 3 | 0 | 3 |
| LRFN1 | BATF2 | 0.732063 | 3 | 0 | 3 |
| LRFN1 | AMPD2 | 0.727251 | 3 | 0 | 3 |
| LRFN1 | PSTPIP1 | 0.722784 | 4 | 0 | 4 |
| LRFN1 | BEND3 | 0.720861 | 4 | 0 | 3 |
| LRFN1 | KCP | 0.720508 | 3 | 0 | 3 |
| LRFN1 | SMG5 | 0.714194 | 3 | 0 | 3 |
| LRFN1 | GLDC | 0.70692 | 3 | 0 | 3 |
| LRFN1 | PALM3 | 0.702244 | 3 | 0 | 3 |
| LRFN1 | SALL3 | 0.697662 | 4 | 0 | 4 |
| LRFN1 | STK32C | 0.69728 | 4 | 0 | 3 |
| LRFN1 | ATXN7L2 | 0.694803 | 4 | 0 | 4 |
| LRFN1 | SEC62 | 0.692059 | 3 | 0 | 3 |
For details and further investigation, click here
