| Full name: BCL2 associated athanogene 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 10q26.11 | ||
| Entrez ID: 9531 | HGNC ID: HGNC:939 | Ensembl Gene: ENSG00000151929 | OMIM ID: 603883 |
| Drug and gene relationship at DGIdb | |||
Expression of BAG3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BAG3 | 9531 | 217911_s_at | -0.5335 | 0.1308 | |
| GSE20347 | BAG3 | 9531 | 217911_s_at | -0.3116 | 0.0163 | |
| GSE23400 | BAG3 | 9531 | 217911_s_at | -0.2090 | 0.0039 | |
| GSE26886 | BAG3 | 9531 | 217911_s_at | 0.0234 | 0.9273 | |
| GSE29001 | BAG3 | 9531 | 217911_s_at | -0.2576 | 0.0838 | |
| GSE38129 | BAG3 | 9531 | 217911_s_at | -0.2420 | 0.1459 | |
| GSE45670 | BAG3 | 9531 | 217911_s_at | -0.0439 | 0.8959 | |
| GSE53622 | BAG3 | 9531 | 8345 | -0.3796 | 0.0002 | |
| GSE53624 | BAG3 | 9531 | 8345 | -0.1773 | 0.0124 | |
| GSE63941 | BAG3 | 9531 | 217911_s_at | -0.9364 | 0.0918 | |
| GSE77861 | BAG3 | 9531 | 217911_s_at | -0.2194 | 0.2622 | |
| GSE97050 | BAG3 | 9531 | A_23_P47077 | -0.0342 | 0.9183 | |
| SRP007169 | BAG3 | 9531 | RNAseq | -2.6515 | 0.0002 | |
| SRP008496 | BAG3 | 9531 | RNAseq | -2.1853 | 0.0000 | |
| SRP064894 | BAG3 | 9531 | RNAseq | -0.6325 | 0.0014 | |
| SRP133303 | BAG3 | 9531 | RNAseq | -0.3805 | 0.0280 | |
| SRP159526 | BAG3 | 9531 | RNAseq | -0.3541 | 0.4059 | |
| SRP193095 | BAG3 | 9531 | RNAseq | -0.2068 | 0.3588 | |
| SRP219564 | BAG3 | 9531 | RNAseq | -1.1285 | 0.0687 | |
| TCGA | BAG3 | 9531 | RNAseq | 0.0029 | 0.9613 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by BAG3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BAG3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BAG3 | 9531 | 2 | 8 | 20 | |
| GSE20123 | BAG3 | 9531 | 2 | 8 | 20 | |
| GSE43470 | BAG3 | 9531 | 0 | 9 | 34 | |
| GSE46452 | BAG3 | 9531 | 0 | 11 | 48 | |
| GSE47630 | BAG3 | 9531 | 2 | 14 | 24 | |
| GSE54993 | BAG3 | 9531 | 8 | 0 | 62 | |
| GSE54994 | BAG3 | 9531 | 1 | 9 | 43 | |
| GSE60625 | BAG3 | 9531 | 0 | 0 | 11 | |
| GSE74703 | BAG3 | 9531 | 0 | 6 | 30 | |
| GSE74704 | BAG3 | 9531 | 1 | 3 | 16 | |
| TCGA | BAG3 | 9531 | 5 | 28 | 63 |
Total number of gains: 21; Total number of losses: 96; Total Number of normals: 371.
Somatic mutations of BAG3:
Generating mutation plots.
Highly correlated genes for BAG3:
Showing top 20/247 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BAG3 | TAF9B | 0.822849 | 3 | 0 | 3 |
| BAG3 | RSRC2 | 0.789212 | 3 | 0 | 3 |
| BAG3 | ZFAND2A | 0.77719 | 4 | 0 | 4 |
| BAG3 | GRIK2 | 0.7607 | 3 | 0 | 3 |
| BAG3 | PBX1 | 0.752252 | 3 | 0 | 3 |
| BAG3 | UBR2 | 0.743985 | 3 | 0 | 3 |
| BAG3 | HABP4 | 0.743464 | 3 | 0 | 3 |
| BAG3 | PARVA | 0.743096 | 3 | 0 | 3 |
| BAG3 | TRA2A | 0.737245 | 3 | 0 | 3 |
| BAG3 | CKMT2 | 0.736399 | 3 | 0 | 3 |
| BAG3 | SELENBP1 | 0.73132 | 3 | 0 | 3 |
| BAG3 | MRVI1 | 0.730398 | 3 | 0 | 3 |
| BAG3 | CSDE1 | 0.72984 | 3 | 0 | 3 |
| BAG3 | EMD | 0.726168 | 3 | 0 | 3 |
| BAG3 | RAB18 | 0.718394 | 3 | 0 | 3 |
| BAG3 | ZNF570 | 0.717389 | 3 | 0 | 3 |
| BAG3 | TRAK1 | 0.71654 | 3 | 0 | 3 |
| BAG3 | MYADM | 0.713989 | 3 | 0 | 3 |
| BAG3 | EIF1AY | 0.711377 | 3 | 0 | 3 |
| BAG3 | MYOCD | 0.70706 | 3 | 0 | 3 |
For details and further investigation, click here
