SELENBP1

 

Full name: selenium binding protein 1 Alias Symbol: hSP56|hSBP|LPSB
Type: protein-coding gene Cytoband: 1q21.3
Entrez ID: 8991 HGNC ID: HGNC:10719 Ensembl Gene: ENSG00000143416 OMIM ID: 604188
Drug and gene relationship at DGIdb

 

Expression of SELENBP1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SELENBP1 8991 214433_s_at -0.9794 0.2916
GSE20347 SELENBP1 8991 214433_s_at -0.6936 0.0083
GSE23400 SELENBP1 8991 214433_s_at -1.1591 0.0000
GSE26886 SELENBP1 8991 214433_s_at -1.4610 0.0003
GSE29001 SELENBP1 8991 214433_s_at -1.2819 0.0002
GSE38129 SELENBP1 8991 214433_s_at -1.3637 0.0000
GSE45670 SELENBP1 8991 214433_s_at -1.7236 0.0000
GSE53622 SELENBP1 8991 46345 -2.0685 0.0000
GSE53624 SELENBP1 8991 46345 -1.9742 0.0000
GSE63941 SELENBP1 8991 214433_s_at -2.8624 0.0768
GSE77861 SELENBP1 8991 214433_s_at -0.5704 0.0117
GSE97050 SELENBP1 8991 A_23_P86021 -0.6915 0.2569
SRP007169 SELENBP1 8991 RNAseq -2.1659 0.0000
SRP064894 SELENBP1 8991 RNAseq -0.9406 0.0317
SRP133303 SELENBP1 8991 RNAseq -1.3415 0.0005
SRP159526 SELENBP1 8991 RNAseq -1.8157 0.0000
SRP193095 SELENBP1 8991 RNAseq -1.4208 0.0029
SRP219564 SELENBP1 8991 RNAseq -0.6006 0.4943
TCGA SELENBP1 8991 RNAseq -1.3050 0.0000

Upregulated datasets: 0; Downregulated datasets: 12.  


 

Survival by SELENBP1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of SELENBP1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SELENBP1 8991 14 0 16
GSE20123 SELENBP1 8991 14 0 16
GSE43470 SELENBP1 8991 6 1 36
GSE46452 SELENBP1 8991 2 1 56
GSE47630 SELENBP1 8991 14 0 26
GSE54993 SELENBP1 8991 0 4 66
GSE54994 SELENBP1 8991 15 0 38
GSE60625 SELENBP1 8991 0 0 11
GSE74703 SELENBP1 8991 6 1 29
GSE74704 SELENBP1 8991 7 0 13
TCGA SELENBP1 8991 37 2 57

Total number of gains: 115; Total number of losses: 9; Total Number of normals: 364.  


 

Somatic mutations of SELENBP1:

 

Generating mutation plots.

 

Highly correlated genes for SELENBP1:

 

Showing top 20/1587 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SELENBP1ING30.816303303
SELENBP1CLEC3B0.81547303
SELENBP1SORCS10.806441404
SELENBP1CYP21A20.802468303
SELENBP1GGA30.791722303
SELENBP1FRMD30.759236505
SELENBP1ARHGEF90.758457909
SELENBP1HLF0.7542311011
SELENBP1SORBS20.7524311011
SELENBP1TCEAL60.749014303
SELENBP1MACROD20.748894403
SELENBP1A2M-AS10.747245303
SELENBP1EIF4E30.7461707
SELENBP1NR2F10.745306303
SELENBP1ZMAT10.743935606
SELENBP1PREX20.743447404
SELENBP1XKR40.741207605
SELENBP1KIAA11430.739944303
SELENBP1TNFSF120.738192303
SELENBP1CFD0.736944909

For details and further investigation, click here