| Full name: transformer 2 alpha homolog | Alias Symbol: htra-2-alpha|tra2a|AWMS1 | ||
| Type: protein-coding gene | Cytoband: 7p15.3 | ||
| Entrez ID: 29896 | HGNC ID: HGNC:16645 | Ensembl Gene: ENSG00000164548 | OMIM ID: 602718 |
| Drug and gene relationship at DGIdb | |||
Expression of TRA2A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TRA2A | 29896 | 204658_at | -0.3355 | 0.2074 | |
| GSE20347 | TRA2A | 29896 | 213593_s_at | 0.0198 | 0.9383 | |
| GSE23400 | TRA2A | 29896 | 204658_at | -0.1635 | 0.0508 | |
| GSE26886 | TRA2A | 29896 | 229574_at | -0.5499 | 0.1417 | |
| GSE29001 | TRA2A | 29896 | 213593_s_at | -0.2335 | 0.4598 | |
| GSE38129 | TRA2A | 29896 | 213593_s_at | 0.0234 | 0.9659 | |
| GSE45670 | TRA2A | 29896 | 204658_at | 0.0794 | 0.5574 | |
| GSE53622 | TRA2A | 29896 | 49144 | -0.1875 | 0.0013 | |
| GSE53624 | TRA2A | 29896 | 49144 | -0.5106 | 0.0000 | |
| GSE63941 | TRA2A | 29896 | 204658_at | -0.1052 | 0.8521 | |
| GSE77861 | TRA2A | 29896 | 204658_at | -0.2706 | 0.3510 | |
| GSE97050 | TRA2A | 29896 | A_23_P31389 | -0.1247 | 0.5556 | |
| SRP007169 | TRA2A | 29896 | RNAseq | -0.1980 | 0.5757 | |
| SRP008496 | TRA2A | 29896 | RNAseq | -0.0512 | 0.8304 | |
| SRP064894 | TRA2A | 29896 | RNAseq | -0.5577 | 0.0004 | |
| SRP133303 | TRA2A | 29896 | RNAseq | -0.0879 | 0.5900 | |
| SRP159526 | TRA2A | 29896 | RNAseq | -0.3603 | 0.0989 | |
| SRP193095 | TRA2A | 29896 | RNAseq | -0.4274 | 0.0003 | |
| SRP219564 | TRA2A | 29896 | RNAseq | -0.3257 | 0.2561 | |
| TCGA | TRA2A | 29896 | RNAseq | 0.0158 | 0.7585 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TRA2A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TRA2A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TRA2A | 29896 | 17 | 1 | 12 | |
| GSE20123 | TRA2A | 29896 | 17 | 1 | 12 | |
| GSE43470 | TRA2A | 29896 | 4 | 0 | 39 | |
| GSE46452 | TRA2A | 29896 | 10 | 2 | 47 | |
| GSE47630 | TRA2A | 29896 | 9 | 1 | 30 | |
| GSE54993 | TRA2A | 29896 | 0 | 6 | 64 | |
| GSE54994 | TRA2A | 29896 | 20 | 3 | 30 | |
| GSE60625 | TRA2A | 29896 | 0 | 0 | 11 | |
| GSE74703 | TRA2A | 29896 | 4 | 0 | 32 | |
| GSE74704 | TRA2A | 29896 | 11 | 1 | 8 | |
| TCGA | TRA2A | 29896 | 56 | 4 | 36 |
Total number of gains: 148; Total number of losses: 19; Total Number of normals: 321.
Somatic mutations of TRA2A:
Generating mutation plots.
Highly correlated genes for TRA2A:
Showing top 20/208 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TRA2A | FRAS1 | 0.754297 | 3 | 0 | 3 |
| TRA2A | FIG4 | 0.750188 | 3 | 0 | 3 |
| TRA2A | C3orf38 | 0.741584 | 3 | 0 | 3 |
| TRA2A | BAG3 | 0.737245 | 3 | 0 | 3 |
| TRA2A | THOC1 | 0.731117 | 3 | 0 | 3 |
| TRA2A | TMEM126A | 0.729081 | 3 | 0 | 3 |
| TRA2A | EXD2 | 0.726999 | 3 | 0 | 3 |
| TRA2A | BTN1A1 | 0.720224 | 3 | 0 | 3 |
| TRA2A | LRRC37A2 | 0.71839 | 3 | 0 | 3 |
| TRA2A | PLEKHA5 | 0.718201 | 3 | 0 | 3 |
| TRA2A | FBXL3 | 0.713836 | 3 | 0 | 3 |
| TRA2A | SLC35A1 | 0.71254 | 4 | 0 | 3 |
| TRA2A | ALDH1A2 | 0.711047 | 3 | 0 | 3 |
| TRA2A | POLI | 0.706959 | 3 | 0 | 3 |
| TRA2A | USP34 | 0.700278 | 4 | 0 | 3 |
| TRA2A | GNL3 | 0.696872 | 3 | 0 | 3 |
| TRA2A | PPA1 | 0.696793 | 3 | 0 | 3 |
| TRA2A | TBRG1 | 0.695348 | 3 | 0 | 3 |
| TRA2A | VEZT | 0.69253 | 4 | 0 | 3 |
| TRA2A | ZNF546 | 0.692414 | 3 | 0 | 3 |
For details and further investigation, click here
