| Full name: trafficking kinesin protein 1 | Alias Symbol: OIP106|KIAA1042|MILT1 | ||
| Type: protein-coding gene | Cytoband: 3p22.1 | ||
| Entrez ID: 22906 | HGNC ID: HGNC:29947 | Ensembl Gene: ENSG00000182606 | OMIM ID: 608112 |
| Drug and gene relationship at DGIdb | |||
Expression of TRAK1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TRAK1 | 22906 | 202080_s_at | -0.2612 | 0.4065 | |
| GSE20347 | TRAK1 | 22906 | 214924_s_at | -0.5894 | 0.0008 | |
| GSE23400 | TRAK1 | 22906 | 202080_s_at | -0.1725 | 0.0033 | |
| GSE26886 | TRAK1 | 22906 | 214924_s_at | -0.2872 | 0.1239 | |
| GSE29001 | TRAK1 | 22906 | 214924_s_at | -0.7171 | 0.0192 | |
| GSE38129 | TRAK1 | 22906 | 202080_s_at | -0.5537 | 0.0000 | |
| GSE45670 | TRAK1 | 22906 | 214924_s_at | -0.0460 | 0.7953 | |
| GSE53622 | TRAK1 | 22906 | 33932 | -0.6905 | 0.0000 | |
| GSE53624 | TRAK1 | 22906 | 5933 | -0.9559 | 0.0000 | |
| GSE63941 | TRAK1 | 22906 | 214924_s_at | 0.1937 | 0.6364 | |
| GSE77861 | TRAK1 | 22906 | 214924_s_at | -0.1197 | 0.5127 | |
| GSE97050 | TRAK1 | A_21_P0013927 | -0.1356 | 0.6194 | ||
| SRP007169 | TRAK1 | 22906 | RNAseq | 0.5059 | 0.2611 | |
| SRP008496 | TRAK1 | 22906 | RNAseq | 0.1627 | 0.5368 | |
| SRP064894 | TRAK1 | 22906 | RNAseq | -0.4987 | 0.0046 | |
| SRP133303 | TRAK1 | 22906 | RNAseq | -0.7187 | 0.0000 | |
| SRP159526 | TRAK1 | 22906 | RNAseq | -0.6010 | 0.0323 | |
| SRP193095 | TRAK1 | 22906 | RNAseq | -0.7490 | 0.0000 | |
| SRP219564 | TRAK1 | 22906 | RNAseq | -0.8125 | 0.0010 | |
| TCGA | TRAK1 | 22906 | RNAseq | -0.3657 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TRAK1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TRAK1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TRAK1 | 22906 | 0 | 19 | 11 | |
| GSE20123 | TRAK1 | 22906 | 0 | 19 | 11 | |
| GSE43470 | TRAK1 | 22906 | 0 | 21 | 22 | |
| GSE46452 | TRAK1 | 22906 | 2 | 17 | 40 | |
| GSE47630 | TRAK1 | 22906 | 2 | 23 | 15 | |
| GSE54993 | TRAK1 | 22906 | 7 | 2 | 61 | |
| GSE54994 | TRAK1 | 22906 | 1 | 34 | 18 | |
| GSE60625 | TRAK1 | 22906 | 5 | 0 | 6 | |
| GSE74703 | TRAK1 | 22906 | 0 | 17 | 19 | |
| GSE74704 | TRAK1 | 22906 | 0 | 13 | 7 | |
| TCGA | TRAK1 | 22906 | 1 | 71 | 24 |
Total number of gains: 18; Total number of losses: 236; Total Number of normals: 234.
Somatic mutations of TRAK1:
Generating mutation plots.
Highly correlated genes for TRAK1:
Showing top 20/774 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TRAK1 | RHOU | 0.832063 | 3 | 0 | 3 |
| TRAK1 | LRFN5 | 0.820635 | 3 | 0 | 3 |
| TRAK1 | MRGPRF | 0.811977 | 3 | 0 | 3 |
| TRAK1 | RASSF3 | 0.784113 | 4 | 0 | 4 |
| TRAK1 | LSM11 | 0.782518 | 3 | 0 | 3 |
| TRAK1 | NME5 | 0.778093 | 4 | 0 | 4 |
| TRAK1 | SORCS1 | 0.777334 | 4 | 0 | 4 |
| TRAK1 | NEXN | 0.773222 | 3 | 0 | 3 |
| TRAK1 | FRMD3 | 0.771554 | 3 | 0 | 3 |
| TRAK1 | FNDC5 | 0.770711 | 3 | 0 | 3 |
| TRAK1 | PLIN4 | 0.769605 | 3 | 0 | 3 |
| TRAK1 | RBM24 | 0.767762 | 3 | 0 | 3 |
| TRAK1 | MYOCD | 0.75151 | 4 | 0 | 4 |
| TRAK1 | PODN | 0.748156 | 3 | 0 | 3 |
| TRAK1 | RECK | 0.74674 | 3 | 0 | 3 |
| TRAK1 | GNPDA2 | 0.746563 | 3 | 0 | 3 |
| TRAK1 | CLEC3B | 0.743602 | 3 | 0 | 3 |
| TRAK1 | NIPSNAP3B | 0.737541 | 3 | 0 | 3 |
| TRAK1 | ANO5 | 0.737409 | 4 | 0 | 3 |
| TRAK1 | SYNC | 0.736657 | 4 | 0 | 3 |
For details and further investigation, click here
