| Full name: parvin alpha | Alias Symbol: FLJ12254|FLJ10793 | ||
| Type: protein-coding gene | Cytoband: 11p15.3 | ||
| Entrez ID: 55742 | HGNC ID: HGNC:14652 | Ensembl Gene: ENSG00000197702 | OMIM ID: 608120 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
PARVA involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04510 | Focal adhesion |
Expression of PARVA:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PARVA | 55742 | 217890_s_at | -0.9684 | 0.2781 | |
| GSE20347 | PARVA | 55742 | 217890_s_at | -0.4592 | 0.0126 | |
| GSE23400 | PARVA | 55742 | 217890_s_at | -0.1392 | 0.2666 | |
| GSE26886 | PARVA | 55742 | 217890_s_at | 0.6394 | 0.0091 | |
| GSE29001 | PARVA | 55742 | 217890_s_at | -0.2176 | 0.5000 | |
| GSE38129 | PARVA | 55742 | 217890_s_at | -0.7738 | 0.0203 | |
| GSE45670 | PARVA | 55742 | 217890_s_at | -1.3473 | 0.0000 | |
| GSE53622 | PARVA | 55742 | 56515 | -0.6489 | 0.0000 | |
| GSE53624 | PARVA | 55742 | 56515 | -0.4534 | 0.0000 | |
| GSE63941 | PARVA | 55742 | 217890_s_at | -3.9397 | 0.0007 | |
| GSE77861 | PARVA | 55742 | 217890_s_at | -0.0682 | 0.8639 | |
| GSE97050 | PARVA | 55742 | A_24_P124370 | -0.6917 | 0.1057 | |
| SRP007169 | PARVA | 55742 | RNAseq | 0.7143 | 0.0242 | |
| SRP008496 | PARVA | 55742 | RNAseq | 0.8590 | 0.0010 | |
| SRP064894 | PARVA | 55742 | RNAseq | -0.2345 | 0.3357 | |
| SRP133303 | PARVA | 55742 | RNAseq | 0.0264 | 0.9263 | |
| SRP159526 | PARVA | 55742 | RNAseq | -0.8270 | 0.0061 | |
| SRP193095 | PARVA | 55742 | RNAseq | 0.2628 | 0.0754 | |
| SRP219564 | PARVA | 55742 | RNAseq | -0.4625 | 0.5062 | |
| TCGA | PARVA | 55742 | RNAseq | -0.2543 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by PARVA expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PARVA:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PARVA | 55742 | 0 | 9 | 21 | |
| GSE20123 | PARVA | 55742 | 0 | 9 | 21 | |
| GSE43470 | PARVA | 55742 | 1 | 5 | 37 | |
| GSE46452 | PARVA | 55742 | 7 | 5 | 47 | |
| GSE47630 | PARVA | 55742 | 3 | 11 | 26 | |
| GSE54993 | PARVA | 55742 | 3 | 1 | 66 | |
| GSE54994 | PARVA | 55742 | 4 | 12 | 37 | |
| GSE60625 | PARVA | 55742 | 0 | 0 | 11 | |
| GSE74703 | PARVA | 55742 | 1 | 3 | 32 | |
| GSE74704 | PARVA | 55742 | 0 | 7 | 13 | |
| TCGA | PARVA | 55742 | 11 | 32 | 53 |
Total number of gains: 30; Total number of losses: 94; Total Number of normals: 364.
Somatic mutations of PARVA:
Generating mutation plots.
Highly correlated genes for PARVA:
Showing top 20/1160 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PARVA | MGARP | 0.822304 | 3 | 0 | 3 |
| PARVA | ZEB1 | 0.816316 | 3 | 0 | 3 |
| PARVA | ILK | 0.811839 | 9 | 0 | 9 |
| PARVA | UBXN10 | 0.792146 | 3 | 0 | 3 |
| PARVA | MSRB3 | 0.789947 | 7 | 0 | 7 |
| PARVA | DDR2 | 0.787775 | 10 | 0 | 10 |
| PARVA | CYS1 | 0.787245 | 6 | 0 | 6 |
| PARVA | SMIM10 | 0.780672 | 5 | 0 | 5 |
| PARVA | ZCCHC24 | 0.777541 | 10 | 0 | 9 |
| PARVA | PRICKLE2 | 0.777114 | 6 | 0 | 6 |
| PARVA | MRGPRF | 0.775047 | 8 | 0 | 8 |
| PARVA | FNBP1 | 0.772152 | 7 | 0 | 7 |
| PARVA | PDLIM3 | 0.760984 | 12 | 0 | 12 |
| PARVA | DSTN | 0.754244 | 9 | 0 | 8 |
| PARVA | MRVI1 | 0.752726 | 8 | 0 | 7 |
| PARVA | MIR100HG | 0.75242 | 6 | 0 | 5 |
| PARVA | ANTXR2 | 0.74801 | 8 | 0 | 7 |
| PARVA | PRKACB | 0.747513 | 8 | 0 | 7 |
| PARVA | PGR | 0.745362 | 5 | 0 | 5 |
| PARVA | PDZRN4 | 0.743197 | 9 | 0 | 9 |
For details and further investigation, click here
