| Full name: BAF chromatin remodeling complex subunit BCL7C | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 16p11.2 | ||
| Entrez ID: 9274 | HGNC ID: HGNC:1006 | Ensembl Gene: ENSG00000099385 | OMIM ID: 605847 |
| Drug and gene relationship at DGIdb | |||
Expression of BCL7C:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BCL7C | 9274 | 219072_at | 0.2168 | 0.5573 | |
| GSE20347 | BCL7C | 9274 | 219072_at | -0.0045 | 0.9792 | |
| GSE23400 | BCL7C | 9274 | 219072_at | 0.0147 | 0.7987 | |
| GSE26886 | BCL7C | 9274 | 219072_at | 0.6223 | 0.0006 | |
| GSE29001 | BCL7C | 9274 | 219072_at | 0.0837 | 0.7458 | |
| GSE38129 | BCL7C | 9274 | 219072_at | 0.0462 | 0.7484 | |
| GSE45670 | BCL7C | 9274 | 219072_at | -0.0129 | 0.9314 | |
| GSE53622 | BCL7C | 9274 | 33773 | 0.0810 | 0.1534 | |
| GSE53624 | BCL7C | 9274 | 33773 | 0.3158 | 0.0000 | |
| GSE63941 | BCL7C | 9274 | 219072_at | 0.6313 | 0.0697 | |
| GSE77861 | BCL7C | 9274 | 219072_at | 0.2088 | 0.3535 | |
| GSE97050 | BCL7C | 9274 | A_23_P118289 | 0.1745 | 0.5129 | |
| SRP007169 | BCL7C | 9274 | RNAseq | -0.5145 | 0.1445 | |
| SRP008496 | BCL7C | 9274 | RNAseq | -0.2349 | 0.3207 | |
| SRP064894 | BCL7C | 9274 | RNAseq | 0.2161 | 0.5822 | |
| SRP133303 | BCL7C | 9274 | RNAseq | 0.4047 | 0.0327 | |
| SRP159526 | BCL7C | 9274 | RNAseq | 0.5130 | 0.0133 | |
| SRP193095 | BCL7C | 9274 | RNAseq | 0.0466 | 0.7445 | |
| SRP219564 | BCL7C | 9274 | RNAseq | 0.1256 | 0.7337 | |
| TCGA | BCL7C | 9274 | RNAseq | 0.0882 | 0.1468 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by BCL7C expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BCL7C:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BCL7C | 9274 | 5 | 5 | 20 | |
| GSE20123 | BCL7C | 9274 | 5 | 4 | 21 | |
| GSE43470 | BCL7C | 9274 | 3 | 3 | 37 | |
| GSE46452 | BCL7C | 9274 | 38 | 1 | 20 | |
| GSE47630 | BCL7C | 9274 | 11 | 7 | 22 | |
| GSE54993 | BCL7C | 9274 | 2 | 5 | 63 | |
| GSE54994 | BCL7C | 9274 | 5 | 9 | 39 | |
| GSE60625 | BCL7C | 9274 | 4 | 0 | 7 | |
| GSE74703 | BCL7C | 9274 | 3 | 2 | 31 | |
| GSE74704 | BCL7C | 9274 | 3 | 2 | 15 | |
| TCGA | BCL7C | 9274 | 20 | 10 | 66 |
Total number of gains: 99; Total number of losses: 48; Total Number of normals: 341.
Somatic mutations of BCL7C:
Generating mutation plots.
Highly correlated genes for BCL7C:
Showing top 20/974 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BCL7C | NOTCH3 | 0.821882 | 3 | 0 | 3 |
| BCL7C | XPO1 | 0.802321 | 3 | 0 | 3 |
| BCL7C | PDPR | 0.780434 | 3 | 0 | 3 |
| BCL7C | ROMO1 | 0.778403 | 3 | 0 | 3 |
| BCL7C | EVI5L | 0.76594 | 3 | 0 | 3 |
| BCL7C | FAM171B | 0.764713 | 4 | 0 | 4 |
| BCL7C | TMEM25 | 0.756859 | 3 | 0 | 3 |
| BCL7C | ARL16 | 0.746644 | 3 | 0 | 3 |
| BCL7C | FAM168A | 0.74538 | 3 | 0 | 3 |
| BCL7C | ADH5 | 0.740314 | 3 | 0 | 3 |
| BCL7C | ANKRD9 | 0.73915 | 3 | 0 | 3 |
| BCL7C | CNNM3 | 0.736686 | 3 | 0 | 3 |
| BCL7C | NUB1 | 0.734175 | 3 | 0 | 3 |
| BCL7C | FTSJ1 | 0.726315 | 3 | 0 | 3 |
| BCL7C | ZSCAN21 | 0.726016 | 3 | 0 | 3 |
| BCL7C | ABCB6 | 0.72573 | 3 | 0 | 3 |
| BCL7C | CHD3 | 0.724375 | 3 | 0 | 3 |
| BCL7C | HNRNPUL1 | 0.723025 | 3 | 0 | 3 |
| BCL7C | MSTO1 | 0.721525 | 3 | 0 | 3 |
| BCL7C | INPP5B | 0.721469 | 4 | 0 | 4 |
For details and further investigation, click here
