| Full name: transmembrane protein 25 | Alias Symbol: FLJ14399 | ||
| Type: protein-coding gene | Cytoband: 11q23.3 | ||
| Entrez ID: 84866 | HGNC ID: HGNC:25890 | Ensembl Gene: ENSG00000149582 | OMIM ID: 613934 |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM25:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM25 | 84866 | 226647_at | 0.2241 | 0.6936 | |
| GSE26886 | TMEM25 | 84866 | 226647_at | 0.4365 | 0.0423 | |
| GSE45670 | TMEM25 | 84866 | 226647_at | -0.2526 | 0.0237 | |
| GSE53622 | TMEM25 | 84866 | 83098 | -0.4022 | 0.0009 | |
| GSE53624 | TMEM25 | 84866 | 83098 | -0.3353 | 0.0002 | |
| GSE63941 | TMEM25 | 84866 | 226647_at | -0.2855 | 0.4282 | |
| GSE77861 | TMEM25 | 84866 | 226647_at | -0.2730 | 0.0258 | |
| GSE97050 | TMEM25 | 84866 | A_24_P133017 | -0.4661 | 0.2575 | |
| SRP007169 | TMEM25 | 84866 | RNAseq | -0.8526 | 0.0944 | |
| SRP008496 | TMEM25 | 84866 | RNAseq | -0.1730 | 0.7382 | |
| SRP064894 | TMEM25 | 84866 | RNAseq | -0.2532 | 0.4033 | |
| SRP133303 | TMEM25 | 84866 | RNAseq | -0.7946 | 0.0000 | |
| SRP159526 | TMEM25 | 84866 | RNAseq | 0.4667 | 0.0397 | |
| SRP193095 | TMEM25 | 84866 | RNAseq | -0.2791 | 0.0968 | |
| SRP219564 | TMEM25 | 84866 | RNAseq | -0.5588 | 0.3478 | |
| TCGA | TMEM25 | 84866 | RNAseq | -0.4308 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TMEM25 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM25:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM25 | 84866 | 2 | 11 | 17 | |
| GSE20123 | TMEM25 | 84866 | 2 | 11 | 17 | |
| GSE43470 | TMEM25 | 84866 | 2 | 9 | 32 | |
| GSE46452 | TMEM25 | 84866 | 3 | 26 | 30 | |
| GSE47630 | TMEM25 | 84866 | 2 | 19 | 19 | |
| GSE54993 | TMEM25 | 84866 | 10 | 0 | 60 | |
| GSE54994 | TMEM25 | 84866 | 5 | 19 | 29 | |
| GSE60625 | TMEM25 | 84866 | 0 | 3 | 8 | |
| GSE74703 | TMEM25 | 84866 | 1 | 6 | 29 | |
| GSE74704 | TMEM25 | 84866 | 1 | 7 | 12 | |
| TCGA | TMEM25 | 84866 | 4 | 51 | 41 |
Total number of gains: 32; Total number of losses: 162; Total Number of normals: 294.
Somatic mutations of TMEM25:
Generating mutation plots.
Highly correlated genes for TMEM25:
Showing top 20/198 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM25 | GNPAT | 0.758894 | 3 | 0 | 3 |
| TMEM25 | BCL7C | 0.756859 | 3 | 0 | 3 |
| TMEM25 | USP13 | 0.75386 | 3 | 0 | 3 |
| TMEM25 | NHLRC2 | 0.749021 | 3 | 0 | 3 |
| TMEM25 | HIBADH | 0.721148 | 3 | 0 | 3 |
| TMEM25 | HADH | 0.71802 | 4 | 0 | 3 |
| TMEM25 | NIPAL3 | 0.703216 | 3 | 0 | 3 |
| TMEM25 | FOXN3 | 0.700357 | 3 | 0 | 3 |
| TMEM25 | KLHDC2 | 0.691073 | 3 | 0 | 3 |
| TMEM25 | HLCS | 0.68187 | 4 | 0 | 4 |
| TMEM25 | RBM6 | 0.678189 | 3 | 0 | 3 |
| TMEM25 | CRIP1 | 0.678068 | 3 | 0 | 3 |
| TMEM25 | DFFA | 0.674978 | 3 | 0 | 3 |
| TMEM25 | CDIPT | 0.674412 | 3 | 0 | 3 |
| TMEM25 | SORT1 | 0.671767 | 4 | 0 | 3 |
| TMEM25 | ZNF362 | 0.670338 | 3 | 0 | 3 |
| TMEM25 | SYN3 | 0.66931 | 3 | 0 | 3 |
| TMEM25 | PHC2 | 0.668184 | 4 | 0 | 4 |
| TMEM25 | LIG3 | 0.667597 | 3 | 0 | 3 |
| TMEM25 | ANKS3 | 0.66521 | 4 | 0 | 4 |
For details and further investigation, click here
