| Full name: ATP binding cassette subfamily B member 6 (Langereis blood group) | Alias Symbol: EST45597|umat|MTABC3 | ||
| Type: protein-coding gene | Cytoband: 2q35 | ||
| Entrez ID: 10058 | HGNC ID: HGNC:47 | Ensembl Gene: ENSG00000115657 | OMIM ID: 605452 |
| Drug and gene relationship at DGIdb | |||
Expression of ABCB6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ABCB6 | 10058 | 203192_at | 0.3051 | 0.6076 | |
| GSE20347 | ABCB6 | 10058 | 203192_at | 0.0702 | 0.8072 | |
| GSE23400 | ABCB6 | 10058 | 203192_at | 0.3086 | 0.0095 | |
| GSE26886 | ABCB6 | 10058 | 203192_at | -0.0541 | 0.8907 | |
| GSE29001 | ABCB6 | 10058 | 203192_at | -0.0288 | 0.9404 | |
| GSE38129 | ABCB6 | 10058 | 203192_at | 0.2418 | 0.2848 | |
| GSE45670 | ABCB6 | 10058 | 203192_at | 0.5229 | 0.0515 | |
| GSE63941 | ABCB6 | 10058 | 203192_at | -0.0216 | 0.9848 | |
| GSE77861 | ABCB6 | 10058 | 203192_at | 0.8677 | 0.0461 | |
| GSE97050 | ABCB6 | 10058 | A_23_P5441 | 0.2925 | 0.3199 | |
| SRP007169 | ABCB6 | 10058 | RNAseq | 0.6854 | 0.0908 | |
| SRP008496 | ABCB6 | 10058 | RNAseq | 0.5922 | 0.0874 | |
| SRP064894 | ABCB6 | 10058 | RNAseq | 0.3129 | 0.1373 | |
| SRP133303 | ABCB6 | 10058 | RNAseq | 0.3697 | 0.1877 | |
| SRP159526 | ABCB6 | 10058 | RNAseq | 1.3343 | 0.0000 | |
| SRP193095 | ABCB6 | 10058 | RNAseq | 0.3749 | 0.0434 | |
| SRP219564 | ABCB6 | 10058 | RNAseq | 0.2224 | 0.6101 | |
| TCGA | ABCB6 | 10058 | RNAseq | 0.2942 | 0.0116 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ABCB6 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of ABCB6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ABCB6 | 10058 | 2 | 14 | 14 | |
| GSE20123 | ABCB6 | 10058 | 2 | 13 | 15 | |
| GSE43470 | ABCB6 | 10058 | 1 | 7 | 35 | |
| GSE46452 | ABCB6 | 10058 | 0 | 5 | 54 | |
| GSE47630 | ABCB6 | 10058 | 4 | 5 | 31 | |
| GSE54993 | ABCB6 | 10058 | 1 | 2 | 67 | |
| GSE54994 | ABCB6 | 10058 | 8 | 9 | 36 | |
| GSE60625 | ABCB6 | 10058 | 0 | 3 | 8 | |
| GSE74703 | ABCB6 | 10058 | 1 | 5 | 30 | |
| GSE74704 | ABCB6 | 10058 | 2 | 7 | 11 | |
| TCGA | ABCB6 | 10058 | 12 | 26 | 58 |
Total number of gains: 33; Total number of losses: 96; Total Number of normals: 359.
Somatic mutations of ABCB6:
Generating mutation plots.
Highly correlated genes for ABCB6:
Showing top 20/431 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ABCB6 | RAB11FIP5 | 0.847242 | 3 | 0 | 3 |
| ABCB6 | IAH1 | 0.832722 | 3 | 0 | 3 |
| ABCB6 | SLC39A1 | 0.813548 | 3 | 0 | 3 |
| ABCB6 | CYP27C1 | 0.796323 | 3 | 0 | 3 |
| ABCB6 | MB21D2 | 0.787125 | 3 | 0 | 3 |
| ABCB6 | THOC6 | 0.784486 | 3 | 0 | 3 |
| ABCB6 | TUBG1 | 0.782505 | 3 | 0 | 3 |
| ABCB6 | TMEM54 | 0.775422 | 3 | 0 | 3 |
| ABCB6 | LGALSL | 0.763158 | 3 | 0 | 3 |
| ABCB6 | ITGA3 | 0.762852 | 3 | 0 | 3 |
| ABCB6 | BAD | 0.762586 | 3 | 0 | 3 |
| ABCB6 | PSMG3 | 0.753103 | 3 | 0 | 3 |
| ABCB6 | MYO5A | 0.75221 | 3 | 0 | 3 |
| ABCB6 | TNFRSF1A | 0.748578 | 3 | 0 | 3 |
| ABCB6 | NARS2 | 0.747649 | 3 | 0 | 3 |
| ABCB6 | PIGX | 0.747223 | 3 | 0 | 3 |
| ABCB6 | IRF2BPL | 0.743894 | 3 | 0 | 3 |
| ABCB6 | TMEM60 | 0.742172 | 3 | 0 | 3 |
| ABCB6 | POLRMT | 0.740317 | 3 | 0 | 3 |
| ABCB6 | STC2 | 0.73643 | 3 | 0 | 3 |
For details and further investigation, click here
