| Full name: reactive oxygen species modulator 1 | Alias Symbol: bA353C18.2|MTGMP | ||
| Type: protein-coding gene | Cytoband: 20q11.22 | ||
| Entrez ID: 140823 | HGNC ID: HGNC:16185 | Ensembl Gene: ENSG00000125995 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of ROMO1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ROMO1 | 140823 | 224972_at | 0.5061 | 0.0557 | |
| GSE26886 | ROMO1 | 140823 | 224972_at | 1.0260 | 0.0000 | |
| GSE45670 | ROMO1 | 140823 | 224972_at | -0.1098 | 0.4772 | |
| GSE53622 | ROMO1 | 140823 | 78501 | -0.1241 | 0.0824 | |
| GSE53624 | ROMO1 | 140823 | 27799 | -0.0014 | 0.9827 | |
| GSE63941 | ROMO1 | 140823 | 224972_at | 0.6884 | 0.1383 | |
| GSE77861 | ROMO1 | 140823 | 224972_at | -0.3099 | 0.0636 | |
| GSE97050 | ROMO1 | 140823 | A_23_P143414 | 0.1280 | 0.5537 | |
| SRP007169 | ROMO1 | 140823 | RNAseq | -1.5255 | 0.0001 | |
| SRP008496 | ROMO1 | 140823 | RNAseq | -1.2873 | 0.0000 | |
| SRP064894 | ROMO1 | 140823 | RNAseq | 0.5331 | 0.2039 | |
| SRP133303 | ROMO1 | 140823 | RNAseq | -0.2544 | 0.0475 | |
| SRP159526 | ROMO1 | 140823 | RNAseq | -0.0716 | 0.7265 | |
| SRP193095 | ROMO1 | 140823 | RNAseq | -0.7134 | 0.0001 | |
| SRP219564 | ROMO1 | 140823 | RNAseq | -0.1684 | 0.5694 | |
| TCGA | ROMO1 | 140823 | RNAseq | 0.1549 | 0.0197 |
Upregulated datasets: 1; Downregulated datasets: 2.
Survival by ROMO1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ROMO1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ROMO1 | 140823 | 15 | 1 | 14 | |
| GSE20123 | ROMO1 | 140823 | 15 | 1 | 14 | |
| GSE43470 | ROMO1 | 140823 | 12 | 0 | 31 | |
| GSE46452 | ROMO1 | 140823 | 29 | 0 | 30 | |
| GSE47630 | ROMO1 | 140823 | 25 | 0 | 15 | |
| GSE54993 | ROMO1 | 140823 | 0 | 17 | 53 | |
| GSE54994 | ROMO1 | 140823 | 24 | 0 | 29 | |
| GSE60625 | ROMO1 | 140823 | 0 | 0 | 11 | |
| GSE74703 | ROMO1 | 140823 | 11 | 0 | 25 | |
| GSE74704 | ROMO1 | 140823 | 11 | 0 | 9 | |
| TCGA | ROMO1 | 140823 | 49 | 3 | 44 |
Total number of gains: 191; Total number of losses: 22; Total Number of normals: 275.
Somatic mutations of ROMO1:
Generating mutation plots.
Highly correlated genes for ROMO1:
Showing top 20/297 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ROMO1 | INTS1 | 0.87274 | 3 | 0 | 3 |
| ROMO1 | DHX37 | 0.853327 | 3 | 0 | 3 |
| ROMO1 | SIVA1 | 0.831804 | 3 | 0 | 3 |
| ROMO1 | SMYD2 | 0.831012 | 3 | 0 | 3 |
| ROMO1 | POFUT1 | 0.83036 | 3 | 0 | 3 |
| ROMO1 | SNX5 | 0.822864 | 3 | 0 | 3 |
| ROMO1 | ANKRD54 | 0.821277 | 3 | 0 | 3 |
| ROMO1 | RGS19 | 0.818862 | 3 | 0 | 3 |
| ROMO1 | CTU2 | 0.814978 | 3 | 0 | 3 |
| ROMO1 | CCM2 | 0.814629 | 3 | 0 | 3 |
| ROMO1 | MED9 | 0.808096 | 3 | 0 | 3 |
| ROMO1 | PTRHD1 | 0.8056 | 3 | 0 | 3 |
| ROMO1 | ZMYND19 | 0.800391 | 3 | 0 | 3 |
| ROMO1 | TOP3A | 0.797609 | 3 | 0 | 3 |
| ROMO1 | PLCG1 | 0.796897 | 3 | 0 | 3 |
| ROMO1 | C12orf65 | 0.790087 | 3 | 0 | 3 |
| ROMO1 | ANAPC10 | 0.789807 | 3 | 0 | 3 |
| ROMO1 | FHOD1 | 0.789755 | 3 | 0 | 3 |
| ROMO1 | MRPL55 | 0.788155 | 3 | 0 | 3 |
| ROMO1 | TRAP1 | 0.787244 | 3 | 0 | 3 |
For details and further investigation, click here
