| Full name: chromosome 5 open reading frame 58 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 5q35.1 | ||
| Entrez ID: 133874 | HGNC ID: HGNC:37272 | Ensembl Gene: ENSG00000234511 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C5orf58:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C5orf58 | 133874 | 1554115_at | -0.2903 | 0.3310 | |
| GSE26886 | C5orf58 | 133874 | 1554115_at | -0.1069 | 0.4105 | |
| GSE45670 | C5orf58 | 133874 | 1554115_at | 0.0883 | 0.4791 | |
| GSE53622 | C5orf58 | 133874 | 48959 | -0.1045 | 0.6387 | |
| GSE53624 | C5orf58 | 133874 | 48959 | 0.0295 | 0.8922 | |
| GSE63941 | C5orf58 | 133874 | 1554115_at | -0.0368 | 0.8463 | |
| GSE77861 | C5orf58 | 133874 | 1554115_at | -0.1675 | 0.2084 | |
| SRP133303 | C5orf58 | 133874 | RNAseq | 0.8547 | 0.0035 | |
| TCGA | C5orf58 | 133874 | RNAseq | 0.4150 | 0.3450 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by C5orf58 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C5orf58:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C5orf58 | 133874 | 1 | 13 | 16 | |
| GSE20123 | C5orf58 | 133874 | 1 | 13 | 16 | |
| GSE43470 | C5orf58 | 133874 | 1 | 9 | 33 | |
| GSE46452 | C5orf58 | 133874 | 0 | 27 | 32 | |
| GSE47630 | C5orf58 | 133874 | 0 | 20 | 20 | |
| GSE54993 | C5orf58 | 133874 | 9 | 2 | 59 | |
| GSE54994 | C5orf58 | 133874 | 2 | 15 | 36 | |
| GSE60625 | C5orf58 | 133874 | 1 | 0 | 10 | |
| GSE74703 | C5orf58 | 133874 | 1 | 6 | 29 | |
| GSE74704 | C5orf58 | 133874 | 0 | 6 | 14 | |
| TCGA | C5orf58 | 133874 | 7 | 36 | 53 |
Total number of gains: 23; Total number of losses: 147; Total Number of normals: 318.
Somatic mutations of C5orf58:
Generating mutation plots.
Highly correlated genes for C5orf58:
Showing all 18 correlated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C5orf58 | CTRC | 0.672478 | 3 | 0 | 3 |
| C5orf58 | ARMC4 | 0.671913 | 3 | 0 | 3 |
| C5orf58 | HOXB1 | 0.668888 | 3 | 0 | 3 |
| C5orf58 | NLRP12 | 0.665336 | 3 | 0 | 3 |
| C5orf58 | TPSD1 | 0.657106 | 3 | 0 | 3 |
| C5orf58 | HPYR1 | 0.626266 | 3 | 0 | 3 |
| C5orf58 | TGM7 | 0.617104 | 3 | 0 | 3 |
| C5orf58 | MYL4 | 0.612096 | 3 | 0 | 3 |
| C5orf58 | OR51M1 | 0.606977 | 3 | 0 | 3 |
| C5orf58 | CA7 | 0.601382 | 3 | 0 | 3 |
| C5orf58 | CCDC30 | 0.596429 | 3 | 0 | 3 |
| C5orf58 | LMNTD1 | 0.59109 | 3 | 0 | 3 |
| C5orf58 | TAS2R41 | 0.583166 | 3 | 0 | 3 |
| C5orf58 | P2RY13 | 0.578577 | 3 | 0 | 3 |
| C5orf58 | FGF23 | 0.576757 | 3 | 0 | 3 |
| C5orf58 | KRT73 | 0.575543 | 4 | 0 | 3 |
| C5orf58 | OR10H3 | 0.556838 | 4 | 0 | 3 |
| C5orf58 | PDYN | 0.548516 | 4 | 0 | 3 |
For details and further investigation, click here
