| Full name: chymotrypsin C | Alias Symbol: CLCR|ELA4 | ||
| Type: protein-coding gene | Cytoband: 1p36.21 | ||
| Entrez ID: 11330 | HGNC ID: HGNC:2523 | Ensembl Gene: ENSG00000162438 | OMIM ID: 601405 |
| Drug and gene relationship at DGIdb | |||
Expression of CTRC:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CTRC | 11330 | 206297_at | -0.0552 | 0.8100 | |
| GSE20347 | CTRC | 11330 | 206297_at | -0.0002 | 0.9986 | |
| GSE23400 | CTRC | 11330 | 206297_at | -0.1868 | 0.0000 | |
| GSE26886 | CTRC | 11330 | 206297_at | 0.2064 | 0.1095 | |
| GSE29001 | CTRC | 11330 | 206297_at | -0.2187 | 0.1381 | |
| GSE38129 | CTRC | 11330 | 206297_at | -0.1027 | 0.2365 | |
| GSE45670 | CTRC | 11330 | 206297_at | -0.0434 | 0.7162 | |
| GSE53622 | CTRC | 11330 | 92346 | 0.1349 | 0.0354 | |
| GSE53624 | CTRC | 11330 | 92346 | 0.1125 | 0.3830 | |
| GSE63941 | CTRC | 11330 | 206297_at | 0.2931 | 0.0926 | |
| GSE77861 | CTRC | 11330 | 206297_at | -0.1553 | 0.1629 | |
| GSE97050 | CTRC | 11330 | A_23_P34852 | -0.6625 | 0.2001 | |
| SRP133303 | CTRC | 11330 | RNAseq | 0.1938 | 0.2619 | |
| SRP193095 | CTRC | 11330 | RNAseq | 0.0938 | 0.6055 | |
| SRP219564 | CTRC | 11330 | RNAseq | -0.0844 | 0.8351 | |
| TCGA | CTRC | 11330 | RNAseq | 1.0944 | 0.3414 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CTRC expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CTRC:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CTRC | 11330 | 0 | 5 | 25 | |
| GSE20123 | CTRC | 11330 | 0 | 4 | 26 | |
| GSE43470 | CTRC | 11330 | 1 | 8 | 34 | |
| GSE46452 | CTRC | 11330 | 7 | 1 | 51 | |
| GSE47630 | CTRC | 11330 | 8 | 3 | 29 | |
| GSE54993 | CTRC | 11330 | 3 | 1 | 66 | |
| GSE54994 | CTRC | 11330 | 10 | 4 | 39 | |
| GSE60625 | CTRC | 11330 | 0 | 0 | 11 | |
| GSE74703 | CTRC | 11330 | 1 | 5 | 30 | |
| GSE74704 | CTRC | 11330 | 0 | 0 | 20 | |
| TCGA | CTRC | 11330 | 11 | 23 | 62 |
Total number of gains: 41; Total number of losses: 54; Total Number of normals: 393.
Somatic mutations of CTRC:
Generating mutation plots.
Highly correlated genes for CTRC:
Showing top 20/877 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CTRC | KLHL4 | 0.730641 | 3 | 0 | 3 |
| CTRC | C6orf226 | 0.710754 | 3 | 0 | 3 |
| CTRC | FGF14 | 0.68993 | 3 | 0 | 3 |
| CTRC | GDF3 | 0.688647 | 3 | 0 | 3 |
| CTRC | RAX2 | 0.688464 | 3 | 0 | 3 |
| CTRC | GSN-AS1 | 0.6854 | 4 | 0 | 4 |
| CTRC | HMCN2 | 0.685338 | 3 | 0 | 3 |
| CTRC | GATA3-AS1 | 0.68007 | 3 | 0 | 3 |
| CTRC | MYH8 | 0.672876 | 3 | 0 | 3 |
| CTRC | C5orf58 | 0.672478 | 3 | 0 | 3 |
| CTRC | SP7 | 0.667592 | 3 | 0 | 3 |
| CTRC | PDE6H | 0.666744 | 4 | 0 | 4 |
| CTRC | CGA | 0.664481 | 5 | 0 | 5 |
| CTRC | CYP2A7 | 0.655229 | 6 | 0 | 6 |
| CTRC | GML | 0.655221 | 4 | 0 | 3 |
| CTRC | HTR4 | 0.652369 | 6 | 0 | 5 |
| CTRC | OR10J1 | 0.651679 | 5 | 0 | 4 |
| CTRC | C1orf105 | 0.65109 | 5 | 0 | 5 |
| CTRC | ABCA4 | 0.650182 | 3 | 0 | 3 |
| CTRC | MAGEC3 | 0.650127 | 3 | 0 | 3 |
For details and further investigation, click here
