| Full name: homeobox B1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 17q21.32 | ||
| Entrez ID: 3211 | HGNC ID: HGNC:5111 | Ensembl Gene: ENSG00000120094 | OMIM ID: 142968 |
| Drug and gene relationship at DGIdb | |||
Expression of HOXB1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HOXB1 | 3211 | 208224_at | -0.1733 | 0.4649 | |
| GSE20347 | HOXB1 | 3211 | 208224_at | -0.0859 | 0.3081 | |
| GSE23400 | HOXB1 | 3211 | 208224_at | -0.2291 | 0.0000 | |
| GSE26886 | HOXB1 | 3211 | 208224_at | 0.1950 | 0.1428 | |
| GSE29001 | HOXB1 | 3211 | 208224_at | -0.1904 | 0.2987 | |
| GSE38129 | HOXB1 | 3211 | 208224_at | -0.2226 | 0.0090 | |
| GSE45670 | HOXB1 | 3211 | 208224_at | 0.0069 | 0.9593 | |
| GSE53622 | HOXB1 | 3211 | 43369 | 0.3316 | 0.0265 | |
| GSE53624 | HOXB1 | 3211 | 43369 | 0.3230 | 0.0154 | |
| GSE63941 | HOXB1 | 3211 | 208224_at | 0.3991 | 0.0518 | |
| GSE77861 | HOXB1 | 3211 | 208224_at | -0.0344 | 0.8094 | |
| TCGA | HOXB1 | 3211 | RNAseq | 3.6213 | 0.0002 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by HOXB1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HOXB1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HOXB1 | 3211 | 5 | 2 | 23 | |
| GSE20123 | HOXB1 | 3211 | 5 | 2 | 23 | |
| GSE43470 | HOXB1 | 3211 | 3 | 1 | 39 | |
| GSE46452 | HOXB1 | 3211 | 32 | 0 | 27 | |
| GSE47630 | HOXB1 | 3211 | 9 | 0 | 31 | |
| GSE54993 | HOXB1 | 3211 | 2 | 4 | 64 | |
| GSE54994 | HOXB1 | 3211 | 10 | 6 | 37 | |
| GSE60625 | HOXB1 | 3211 | 4 | 0 | 7 | |
| GSE74703 | HOXB1 | 3211 | 3 | 1 | 32 | |
| GSE74704 | HOXB1 | 3211 | 4 | 1 | 15 | |
| TCGA | HOXB1 | 3211 | 27 | 6 | 63 |
Total number of gains: 104; Total number of losses: 23; Total Number of normals: 361.
Somatic mutations of HOXB1:
Generating mutation plots.
Highly correlated genes for HOXB1:
Showing top 20/924 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HOXB1 | MUC5AC | 0.72075 | 5 | 0 | 5 |
| HOXB1 | C9orf16 | 0.706024 | 4 | 0 | 4 |
| HOXB1 | MATN1 | 0.672922 | 3 | 0 | 3 |
| HOXB1 | INCENP | 0.670828 | 3 | 0 | 3 |
| HOXB1 | C5orf58 | 0.668888 | 3 | 0 | 3 |
| HOXB1 | TAS2R13 | 0.668607 | 3 | 0 | 3 |
| HOXB1 | OR2H2 | 0.668443 | 8 | 0 | 7 |
| HOXB1 | LIME1 | 0.667168 | 4 | 0 | 4 |
| HOXB1 | COX6A2 | 0.662776 | 8 | 0 | 7 |
| HOXB1 | MPZ | 0.660564 | 4 | 0 | 4 |
| HOXB1 | MASP2 | 0.659323 | 5 | 0 | 4 |
| HOXB1 | TFEB | 0.658965 | 3 | 0 | 3 |
| HOXB1 | CCDC42 | 0.658263 | 3 | 0 | 3 |
| HOXB1 | SLCO5A1 | 0.656559 | 3 | 0 | 3 |
| HOXB1 | APCS | 0.656028 | 4 | 0 | 3 |
| HOXB1 | IL9 | 0.655047 | 3 | 0 | 3 |
| HOXB1 | MAGEC3 | 0.650661 | 4 | 0 | 3 |
| HOXB1 | GFRA3 | 0.648878 | 4 | 0 | 3 |
| HOXB1 | AMELY | 0.646085 | 4 | 0 | 3 |
| HOXB1 | CDC42EP1 | 0.645184 | 3 | 0 | 3 |
For details and further investigation, click here
