| Full name: transglutaminase 7 | Alias Symbol: TGMZ | ||
| Type: protein-coding gene | Cytoband: 15q15.2 | ||
| Entrez ID: 116179 | HGNC ID: HGNC:30790 | Ensembl Gene: ENSG00000159495 | OMIM ID: 606776 |
| Drug and gene relationship at DGIdb | |||
Expression of TGM7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TGM7 | 116179 | 237288_at | -0.2232 | 0.3891 | |
| GSE26886 | TGM7 | 116179 | 237288_at | -0.0134 | 0.9386 | |
| GSE45670 | TGM7 | 116179 | 237288_at | -0.1310 | 0.2837 | |
| GSE53622 | TGM7 | 116179 | 59281 | 0.1198 | 0.1499 | |
| GSE53624 | TGM7 | 116179 | 59281 | 0.1774 | 0.0439 | |
| GSE63941 | TGM7 | 116179 | 237288_at | 0.2222 | 0.0739 | |
| GSE77861 | TGM7 | 116179 | 237288_at | -0.0566 | 0.5964 | |
| GSE97050 | TGM7 | 116179 | A_23_P117896 | 0.2326 | 0.3518 | |
| TCGA | TGM7 | 116179 | RNAseq | 1.8589 | 0.1607 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TGM7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TGM7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TGM7 | 116179 | 4 | 4 | 22 | |
| GSE20123 | TGM7 | 116179 | 4 | 5 | 21 | |
| GSE43470 | TGM7 | 116179 | 3 | 5 | 35 | |
| GSE46452 | TGM7 | 116179 | 3 | 7 | 49 | |
| GSE47630 | TGM7 | 116179 | 8 | 10 | 22 | |
| GSE54993 | TGM7 | 116179 | 4 | 6 | 60 | |
| GSE54994 | TGM7 | 116179 | 5 | 7 | 41 | |
| GSE60625 | TGM7 | 116179 | 4 | 0 | 7 | |
| GSE74703 | TGM7 | 116179 | 3 | 3 | 30 | |
| GSE74704 | TGM7 | 116179 | 3 | 2 | 15 | |
| TCGA | TGM7 | 116179 | 12 | 17 | 67 |
Total number of gains: 53; Total number of losses: 66; Total Number of normals: 369.
Somatic mutations of TGM7:
Generating mutation plots.
Highly correlated genes for TGM7:
Showing top 20/536 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TGM7 | C9orf153 | 0.822722 | 3 | 0 | 3 |
| TGM7 | STRC | 0.784185 | 3 | 0 | 3 |
| TGM7 | GRIK4 | 0.783264 | 3 | 0 | 3 |
| TGM7 | PRLH | 0.778588 | 3 | 0 | 3 |
| TGM7 | FOXE3 | 0.766785 | 3 | 0 | 3 |
| TGM7 | RNF180 | 0.765969 | 4 | 0 | 4 |
| TGM7 | MRGPRG | 0.762388 | 3 | 0 | 3 |
| TGM7 | YY2 | 0.758915 | 3 | 0 | 3 |
| TGM7 | SLC6A3 | 0.75788 | 3 | 0 | 3 |
| TGM7 | LBX2 | 0.75122 | 3 | 0 | 3 |
| TGM7 | PLA2G2C | 0.732006 | 3 | 0 | 3 |
| TGM7 | CORO6 | 0.72733 | 3 | 0 | 3 |
| TGM7 | SPTBN4 | 0.719434 | 6 | 0 | 6 |
| TGM7 | DCDC1 | 0.719354 | 3 | 0 | 3 |
| TGM7 | SP7 | 0.719066 | 4 | 0 | 4 |
| TGM7 | TUBA3D | 0.718361 | 3 | 0 | 3 |
| TGM7 | KRTAP10-12 | 0.715936 | 3 | 0 | 3 |
| TGM7 | CELF5 | 0.715602 | 3 | 0 | 3 |
| TGM7 | C19orf71 | 0.713698 | 3 | 0 | 3 |
| TGM7 | CNOT3 | 0.713191 | 4 | 0 | 3 |
For details and further investigation, click here
