| Full name: carbonic anhydrase 7 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 16q22.1 | ||
| Entrez ID: 766 | HGNC ID: HGNC:1381 | Ensembl Gene: ENSG00000168748 | OMIM ID: 114770 |
| Drug and gene relationship at DGIdb | |||
Expression of CA7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CA7 | 766 | 207504_at | -0.0074 | 0.9822 | |
| GSE20347 | CA7 | 766 | 207504_at | 0.0761 | 0.5624 | |
| GSE23400 | CA7 | 766 | 207504_at | -0.1246 | 0.0041 | |
| GSE26886 | CA7 | 766 | 207504_at | 0.0028 | 0.9870 | |
| GSE29001 | CA7 | 766 | 207504_at | -0.1227 | 0.4264 | |
| GSE38129 | CA7 | 766 | 207504_at | -0.0785 | 0.4773 | |
| GSE45670 | CA7 | 766 | 207504_at | 0.2145 | 0.0099 | |
| GSE53622 | CA7 | 766 | 67668 | -0.0907 | 0.3550 | |
| GSE53624 | CA7 | 766 | 67668 | 0.0749 | 0.2736 | |
| GSE63941 | CA7 | 766 | 207504_at | 0.1805 | 0.1604 | |
| GSE77861 | CA7 | 766 | 207504_at | -0.1462 | 0.1114 | |
| TCGA | CA7 | 766 | RNAseq | 2.4261 | 0.0490 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by CA7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CA7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CA7 | 766 | 8 | 2 | 20 | |
| GSE20123 | CA7 | 766 | 8 | 2 | 20 | |
| GSE43470 | CA7 | 766 | 1 | 8 | 34 | |
| GSE46452 | CA7 | 766 | 38 | 1 | 20 | |
| GSE47630 | CA7 | 766 | 10 | 8 | 22 | |
| GSE54993 | CA7 | 766 | 2 | 4 | 64 | |
| GSE54994 | CA7 | 766 | 8 | 10 | 35 | |
| GSE60625 | CA7 | 766 | 4 | 0 | 7 | |
| GSE74703 | CA7 | 766 | 1 | 5 | 30 | |
| GSE74704 | CA7 | 766 | 5 | 1 | 14 | |
| TCGA | CA7 | 766 | 31 | 11 | 54 |
Total number of gains: 116; Total number of losses: 52; Total Number of normals: 320.
Somatic mutations of CA7:
Generating mutation plots.
Highly correlated genes for CA7:
Showing top 20/1256 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CA7 | MTAP | 0.75602 | 4 | 0 | 4 |
| CA7 | KCNV1 | 0.74988 | 3 | 0 | 3 |
| CA7 | NTNG1 | 0.748303 | 4 | 0 | 4 |
| CA7 | CCL16 | 0.717713 | 4 | 0 | 3 |
| CA7 | CCDC30 | 0.715473 | 6 | 0 | 5 |
| CA7 | IFNA4 | 0.71154 | 5 | 0 | 5 |
| CA7 | OR10H3 | 0.70976 | 6 | 0 | 6 |
| CA7 | KIR3DL1 | 0.706245 | 5 | 0 | 5 |
| CA7 | SERPINA6 | 0.702688 | 4 | 0 | 4 |
| CA7 | CYP2A7 | 0.70242 | 6 | 0 | 5 |
| CA7 | KIR2DS5 | 0.702293 | 6 | 0 | 6 |
| CA7 | KCNJ10 | 0.702261 | 5 | 0 | 5 |
| CA7 | PRPS1L1 | 0.701695 | 4 | 0 | 4 |
| CA7 | IL1RAPL2 | 0.701694 | 6 | 0 | 5 |
| CA7 | CD4 | 0.701545 | 4 | 0 | 4 |
| CA7 | INE1 | 0.700789 | 5 | 0 | 5 |
| CA7 | KIR2DL3 | 0.700319 | 4 | 0 | 4 |
| CA7 | MEPE | 0.698859 | 6 | 0 | 6 |
| CA7 | CIITA | 0.698561 | 6 | 0 | 5 |
| CA7 | MMP19 | 0.697538 | 5 | 0 | 5 |
For details and further investigation, click here
