BTBD9

 

Full name: BTB domain containing 9 Alias Symbol: KIAA1880|dJ322I12.1
Type: protein-coding gene Cytoband: 6p21.2
Entrez ID: 114781 HGNC ID: HGNC:21228 Ensembl Gene: ENSG00000183826 OMIM ID: 611237
Drug and gene relationship at DGIdb
Screen Evidence:
  • Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

 

Expression of BTBD9:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 BTBD9 114781 235248_at -0.4117 0.3328
GSE26886 BTBD9 114781 235248_at 0.0984 0.5610
GSE45670 BTBD9 114781 235248_at -0.0341 0.8542
GSE53622 BTBD9 114781 18939 -0.7985 0.0000
GSE53624 BTBD9 114781 18939 -0.9910 0.0000
GSE63941 BTBD9 114781 235248_at 0.1565 0.6279
GSE77861 BTBD9 114781 235248_at -0.0975 0.4479
GSE97050 BTBD9 114781 A_33_P3356092 -0.3989 0.1496
SRP007169 BTBD9 114781 RNAseq -1.2884 0.0110
SRP008496 BTBD9 114781 RNAseq -0.7268 0.0283
SRP064894 BTBD9 114781 RNAseq -0.5417 0.0045
SRP133303 BTBD9 114781 RNAseq -0.1369 0.2942
SRP159526 BTBD9 114781 RNAseq -0.6315 0.0561
SRP193095 BTBD9 114781 RNAseq -0.4102 0.0000
SRP219564 BTBD9 114781 RNAseq -0.5826 0.0048
TCGA BTBD9 114781 RNAseq -0.2752 0.0000

Upregulated datasets: 0; Downregulated datasets: 1.  


 

Survival by BTBD9 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of BTBD9:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 BTBD9 114781 5 1 24
GSE20123 BTBD9 114781 5 1 24
GSE43470 BTBD9 114781 6 0 37
GSE46452 BTBD9 114781 2 9 48
GSE47630 BTBD9 114781 8 4 28
GSE54993 BTBD9 114781 3 2 65
GSE54994 BTBD9 114781 11 4 38
GSE60625 BTBD9 114781 0 1 10
GSE74703 BTBD9 114781 6 0 30
GSE74704 BTBD9 114781 2 1 17
TCGA BTBD9 114781 14 19 63

Total number of gains: 62; Total number of losses: 42; Total Number of normals: 384.  


 

Somatic mutations of BTBD9:

 

Generating mutation plots.

 

Highly correlated genes for BTBD9:

 

Showing top 20/378 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
BTBD9BARHL20.894479303
BTBD9CLEC18C0.831708303
BTBD9FAM163B0.827718303
BTBD9NOTO0.825266303
BTBD9KRTAP20-10.819656303
BTBD9CRYBB30.81807303
BTBD9MFSD2B0.816379303
BTBD9RNF2220.804077303
BTBD9GALNT90.783287303
BTBD9FXYD20.782994303
BTBD9OR2Z10.781504404
BTBD9HES50.777195303
BTBD9TEN10.775375303
BTBD9NCR10.771094303
BTBD9RNF1510.766435303
BTBD9MAST40.764408404
BTBD9CD164L20.753766303
BTBD9LRRC310.737405303
BTBD9OR10G30.737248303
BTBD9KPRP0.733968303

For details and further investigation, click here