| Full name: Kruppel like factor 15 | Alias Symbol: KKLF | ||
| Type: protein-coding gene | Cytoband: 3q21.3 | ||
| Entrez ID: 28999 | HGNC ID: HGNC:14536 | Ensembl Gene: ENSG00000163884 | OMIM ID: 606465 |
| Drug and gene relationship at DGIdb | |||
Expression of KLF15:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KLF15 | 28999 | 231015_at | -1.7100 | 0.0672 | |
| GSE20347 | KLF15 | 28999 | 221302_at | -0.0511 | 0.5992 | |
| GSE23400 | KLF15 | 28999 | 221302_at | -0.1334 | 0.0000 | |
| GSE26886 | KLF15 | 28999 | 221302_at | -0.0220 | 0.8883 | |
| GSE29001 | KLF15 | 28999 | 221302_at | -0.1389 | 0.3133 | |
| GSE38129 | KLF15 | 28999 | 221302_at | -0.1151 | 0.1976 | |
| GSE45670 | KLF15 | 28999 | 231015_at | -1.6380 | 0.0000 | |
| GSE53622 | KLF15 | 28999 | 136429 | -1.2428 | 0.0000 | |
| GSE53624 | KLF15 | 28999 | 136429 | -1.1209 | 0.0000 | |
| GSE63941 | KLF15 | 28999 | 231015_at | -0.3331 | 0.3668 | |
| GSE77861 | KLF15 | 28999 | 221302_at | -0.0143 | 0.9231 | |
| SRP064894 | KLF15 | 28999 | RNAseq | -1.7732 | 0.0016 | |
| SRP133303 | KLF15 | 28999 | RNAseq | -0.8342 | 0.0027 | |
| SRP159526 | KLF15 | 28999 | RNAseq | -1.6805 | 0.0000 | |
| SRP219564 | KLF15 | 28999 | RNAseq | -0.9536 | 0.1996 | |
| TCGA | KLF15 | 28999 | RNAseq | -1.8838 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by KLF15 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KLF15:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KLF15 | 28999 | 17 | 0 | 13 | |
| GSE20123 | KLF15 | 28999 | 17 | 0 | 13 | |
| GSE43470 | KLF15 | 28999 | 20 | 0 | 23 | |
| GSE46452 | KLF15 | 28999 | 14 | 5 | 40 | |
| GSE47630 | KLF15 | 28999 | 17 | 4 | 19 | |
| GSE54993 | KLF15 | 28999 | 2 | 7 | 61 | |
| GSE54994 | KLF15 | 28999 | 31 | 3 | 19 | |
| GSE60625 | KLF15 | 28999 | 0 | 6 | 5 | |
| GSE74703 | KLF15 | 28999 | 17 | 0 | 19 | |
| GSE74704 | KLF15 | 28999 | 13 | 0 | 7 | |
| TCGA | KLF15 | 28999 | 55 | 7 | 34 |
Total number of gains: 203; Total number of losses: 32; Total Number of normals: 253.
Somatic mutations of KLF15:
Generating mutation plots.
Highly correlated genes for KLF15:
Showing top 20/984 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KLF15 | KRT76 | 0.78062 | 4 | 0 | 4 |
| KLF15 | ADAM11 | 0.758194 | 4 | 0 | 4 |
| KLF15 | UBXN10-AS1 | 0.74213 | 3 | 0 | 3 |
| KLF15 | CHRDL1 | 0.740917 | 3 | 0 | 3 |
| KLF15 | SLC22A13 | 0.735573 | 4 | 0 | 4 |
| KLF15 | LRTM1 | 0.723499 | 4 | 0 | 4 |
| KLF15 | KRTAP5-8 | 0.722939 | 4 | 0 | 4 |
| KLF15 | THEG | 0.718871 | 6 | 0 | 6 |
| KLF15 | APOL5 | 0.718837 | 3 | 0 | 3 |
| KLF15 | BMP15 | 0.717615 | 6 | 0 | 6 |
| KLF15 | SHBG | 0.717097 | 4 | 0 | 4 |
| KLF15 | PDK4 | 0.713692 | 6 | 0 | 6 |
| KLF15 | MAMDC2 | 0.712789 | 4 | 0 | 4 |
| KLF15 | SLC5A5 | 0.711477 | 5 | 0 | 5 |
| KLF15 | TRPV5 | 0.710714 | 3 | 0 | 3 |
| KLF15 | IFNA21 | 0.709452 | 6 | 0 | 6 |
| KLF15 | TMEM167B | 0.708884 | 3 | 0 | 3 |
| KLF15 | KIR2DS2 | 0.708774 | 5 | 0 | 5 |
| KLF15 | PHF7 | 0.707265 | 4 | 0 | 4 |
| KLF15 | CYP4A11 | 0.706878 | 6 | 0 | 6 |
For details and further investigation, click here
