| Full name: leucine rich repeat containing 43 | Alias Symbol: MGC35140 | ||
| Type: protein-coding gene | Cytoband: 12q24.31 | ||
| Entrez ID: 254050 | HGNC ID: HGNC:28562 | Ensembl Gene: ENSG00000158113 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of LRRC43:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LRRC43 | 254050 | 1553728_at | -0.1382 | 0.5756 | |
| GSE26886 | LRRC43 | 254050 | 1553728_at | -0.4900 | 0.0034 | |
| GSE45670 | LRRC43 | 254050 | 1553728_at | 0.2905 | 0.0030 | |
| GSE53622 | LRRC43 | 254050 | 40386 | 0.1367 | 0.3730 | |
| GSE53624 | LRRC43 | 254050 | 40386 | 0.6281 | 0.0000 | |
| GSE63941 | LRRC43 | 254050 | 1553728_at | 0.2391 | 0.1178 | |
| GSE77861 | LRRC43 | 254050 | 1553728_at | 0.0502 | 0.7138 | |
| TCGA | LRRC43 | 254050 | RNAseq | 0.8596 | 0.1123 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LRRC43 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LRRC43:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LRRC43 | 254050 | 5 | 4 | 21 | |
| GSE20123 | LRRC43 | 254050 | 5 | 4 | 21 | |
| GSE43470 | LRRC43 | 254050 | 2 | 2 | 39 | |
| GSE46452 | LRRC43 | 254050 | 9 | 1 | 49 | |
| GSE47630 | LRRC43 | 254050 | 9 | 3 | 28 | |
| GSE54993 | LRRC43 | 254050 | 0 | 5 | 65 | |
| GSE54994 | LRRC43 | 254050 | 5 | 7 | 41 | |
| GSE60625 | LRRC43 | 254050 | 0 | 0 | 11 | |
| GSE74703 | LRRC43 | 254050 | 2 | 1 | 33 | |
| GSE74704 | LRRC43 | 254050 | 4 | 2 | 14 | |
| TCGA | LRRC43 | 254050 | 21 | 10 | 65 |
Total number of gains: 62; Total number of losses: 39; Total Number of normals: 387.
Somatic mutations of LRRC43:
Generating mutation plots.
Highly correlated genes for LRRC43:
Showing top 20/182 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LRRC43 | CDH22 | 0.738902 | 4 | 0 | 4 |
| LRRC43 | TSSK2 | 0.713813 | 3 | 0 | 3 |
| LRRC43 | SLC22A14 | 0.707732 | 3 | 0 | 3 |
| LRRC43 | ADARB2-AS1 | 0.707221 | 4 | 0 | 4 |
| LRRC43 | NLRP8 | 0.704929 | 3 | 0 | 3 |
| LRRC43 | GAL3ST3 | 0.688289 | 3 | 0 | 3 |
| LRRC43 | GSX1 | 0.684984 | 3 | 0 | 3 |
| LRRC43 | CACNA1G | 0.6809 | 3 | 0 | 3 |
| LRRC43 | HAAO | 0.676179 | 3 | 0 | 3 |
| LRRC43 | WNK2 | 0.672699 | 3 | 0 | 3 |
| LRRC43 | MEGF11 | 0.667081 | 3 | 0 | 3 |
| LRRC43 | NPHS2 | 0.666666 | 4 | 0 | 4 |
| LRRC43 | FOXN4 | 0.663567 | 3 | 0 | 3 |
| LRRC43 | CNTFR-AS1 | 0.657967 | 3 | 0 | 3 |
| LRRC43 | KNCN | 0.657293 | 4 | 0 | 3 |
| LRRC43 | CAMK2B | 0.6526 | 4 | 0 | 4 |
| LRRC43 | TUBB3 | 0.650447 | 3 | 0 | 3 |
| LRRC43 | APOC3 | 0.650085 | 3 | 0 | 3 |
| LRRC43 | G6PC | 0.650012 | 3 | 0 | 3 |
| LRRC43 | CNBD2 | 0.647745 | 5 | 0 | 5 |
For details and further investigation, click here
